Filtered By:
Therapy: Cancer Therapy

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 42071 results found since Jan 2013.

The trends of complementary alternative medicine use among cancer patients
The use of complementary and alternative medicine (CAM) is common among cancer patients and it may reflect the individual and societal beliefs on cancer therapy. Our study aimed to evaluate the trends of CAM u...
Source: BMC Complementary and Alternative Medicine - June 8, 2021 Category: Complementary Medicine Authors: Abdul Rahman Jazieh, Khadega A. Abuelgasim, Husam I. Ardah, Mohammad Alkaiyat and Omar B. Da ’ar Tags: Research article Source Type: research

Fertility preservation and cancer: challenges for adolescent and young adult patients
Purpose of review: With increasing survival rates, fertility is an important quality of life concern for many young cancer patients. There is a critical need for improvements in clinical care to ensure patients are well informed about infertility risks and fertility preservation options and to support them in their reproductive decision-making prior to treatment. Recent findings: Several barriers prevent fertility from being adequately addressed in the clinical context. Providers’ and patients’ incomplete or inaccurate understanding of infertility risks exacerbate patients’ reproductive concerns. For female patients...
Source: Current Opinion in Supportive and Palliative Care - January 29, 2016 Category: Palliative Care Tags: SEXUAL AND REPRODUCTIVE HEALTH ISSUES IN CANCER: Edited by Janet Ellis and Elie Isenberg-Grzeda Source Type: research

Ensuring Head and Neck Oncology Patients Receive Recommended Pretreatment Dental Evaluations Quality in Action
Conclusion: This intervention was the first step in creating a sustainable system for ensuring timely preradiation dental evaluation, thereby decreasing the risk of dental complications from H&N cancer therapy.
Source: Journal of Oncology Practice - March 17, 2015 Category: Cancer & Oncology Authors: Margalit, D. N., Losi, S. M., Tishler, R. B., Schoenfeld, J. D., Ann Fugazzotto, J., Stephens, J., Cebulski, A. L., Hammerstrand, E. L., Ma, L., Lopes, H. M., Haddad, R. I., Treister, N. S., Frustino, J. L. Tags: Complications of cancer and cancer treatment, Survivorship, Quality, Quality of care, General public, Patient, Survivor Quality in Action Source Type: research

Autoimmune Cerebellar Ataxia: Treatment Responses and Outcomes in 118 Patients (I4-4B)
CONCLUSION: The autoantibody profile of autoimmune cerebellar ataxias is diverse. Though usually severe, improvements may occur, particularly in patients with non-paraneoplastic disorders and in those harboring autoantibodies directed against neural plasma membrane protein antigens.Disclosure: Dr. Jones has nothing to disclose. Dr. Pittock's institution has received compensation for activities with Alexion Pharmaceuticals, Medimmune, and Chugai Pharma. Dr. Pittock and his institution stand to receive royalty payments in the technology entitled "Neuromyelitis Optica Autoantibodie Dr. Lennon stands to receive royalty payment...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jones, A., Pittock, S., Lennon, V., Eggers, S., Ahlskog, J., McKeon, A. Tags: Infectious, Paraneoplastic, and Autoimmune Encephalopathies: Advances in Clinical Diagnosis and Emerging Insights about Pathogenesis Data Blitz Presentations Source Type: research

Targeting BCL2 with BH3 mimetics: Basic Science and Clinical Application of Venetoclax in CLL and related B cell malignancies.
This article is protected by copyright. All rights reserved. PMID: 27806433 [PubMed - as supplied by publisher]
Source: Clinical Pharmacology and Therapeutics - November 1, 2016 Category: Drugs & Pharmacology Authors: Roberts AW, Huang DC Tags: Clin Pharmacol Ther Source Type: research

Molecular Imaging, How Close to Clinical Precision Medicine in Lung, Brain, Prostate and Breast Cancers
AbstractPrecision medicine is playing a pivotal role in strategies of cancer therapy. Unlike conventional one-size-fits-all chemotherapy or radiotherapy modalities, precision medicine could customize an individual treatment plan for cancer patients to acquire superior efficacy, while minimizing side effects. Precision medicine in cancer therapy relies on precise and timely tumor biological information. Traditional tissue biopsies, however, are often inadequate in meeting this requirement due to cancer heterogeneity, poor tolerance, and invasiveness. Molecular imaging could detect tumor biology characterization in a noninva...
Source: Molecular Imaging and Biology - July 16, 2021 Category: Molecular Biology Source Type: research

The combinational application of photodynamic therapy and nanotechnology in skin cancer treatment: A review
Tissue Cell. 2022 Jun 15;77:101856. doi: 10.1016/j.tice.2022.101856. Online ahead of print.ABSTRACTSkin cancer is considered a risky worldwide disease. Traditional treatments have several weaknesses, necessitating the creation of more effective treatments. In this case, photodynamic therapy and nanotechnology were used to demonstrate their therapeutic efficacy as combinational approaches in treating different types of skin cancer. In this review, we will discuss the photoexcitation mechanism of PDT, its cell destruction capability, and give a comprehensive outlook of the different photosensitizer types. Also, light sources...
Source: Tissue and Cell - June 27, 2022 Category: Cytology Authors: Fadya Adnane Emad El-Zayat Heba Mohamed Fahmy Source Type: research

Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12
Abstract: Although chemokines are well established to function in immunity and endothelial cell activation and proliferation, a rapidly growing literature suggests that CXC Chemokine receptors CXCR3, CXCR4 and CXCR7 are critical in the development and progression of solid tumors. The effect of these chemokine receptors in tumorigenesis is mediated via interactions with shared ligands I-TAC (CXCL11) and SDF-1 (CXCL12). Over the last decade, CXCR4 has been extensively reported to be overexpressed in most human solid tumors and has earned considerable attention toward elucidating its role in cancer metastasis. To enrich the e...
Source: Cytokine and Growth Factor Reviews - September 17, 2012 Category: Molecular Biology Authors: Anup Kumar Singh, Rakesh Kumar Arya, Arun Kumar Trivedi, Sabyasachi Sanyal, Rathindranath Baral, Olivier Dormond, David M. Briscoe, Dipak Datta Source Type: research

A prospective study comparing prophylactic gastrostomy to nutritional counselling with a therapeutic feeding tube if required in head and neck cancer patients undergoing chemoradiotherapy in Thai real‐world practice
ConclusionsThe results of the present study suggest that PGT provided similar quality of life without a reduction in treatment interruption. However, patients with PGT had significantly less weight loss (P = 0.04) during CRT.
Source: Journal of Human Nutrition and Dietetics - March 28, 2016 Category: Nutrition Authors: P. Pramyothin, S. Manyanont, A. Trakarnsanga, J. Petsuksiri, S. Ithimakin Tags: Research Paper Source Type: research

Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives
Post-translational methylation of histone lysine or arginine residues plays important roles in gene regulation and other physiological processes. Aberrant histone methylation caused by a gene mutation, translo...
Source: Journal of Hematology and Oncology - June 17, 2016 Category: Hematology Authors: Yongcheng Song, Fangrui Wu and Jingyu Wu Source Type: research

Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2
Hexokinase-2(HK-2) plays dual roles in glucose metabolism and mediation of cell apoptosis, making it an attractive target for cancer therapy. Chrysin is a natural flavone found in plant extracts which are wide...
Source: Journal of Experimental and Clinical Cancer Research - March 20, 2017 Category: Cancer & Oncology Authors: Dong Xu, Junzhe Jin, Hao Yu, Zheming Zhao, Dongyan Ma, Chundong Zhang and Honglei Jiang Source Type: research

Quantitative and Systems Pharmacology. 1. In Silico Prediction of Drug –Target Interactions of Natural Products Enables New Targeted Cancer Therapy
Journal of Chemical Information and ModelingDOI: 10.1021/acs.jcim.7b00216
Source: Journal of Chemical Information and Modeling - October 13, 2017 Category: Chemistry Authors: Jiansong Fang, Zengrui Wu, Chuipu Cai, Qi Wang, Yun Tang and Feixiong Cheng Source Type: research

Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization
The estrogen receptor (ER) is a ligand-dependant transcription factor expressed in many breast cancers and is the target of many endocrine-based cancer therapies. Genome-wide studies have shown that the ER bin...
Source: Epigenetics and Chromatin - January 29, 2018 Category: Genetics & Stem Cells Authors: Bart Kolendowski, Haider Hassan, Milica Krstic, Majdina Isovic, Gobi Thillainadesan, Ann F. Chambers, Alan B. Tuck and Joseph Torchia Tags: Research Source Type: research

Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective...
Source: BMC Complementary and Alternative Medicine - January 30, 2018 Category: Complementary Medicine Authors: Victor Kuete, Dominique Ngnintedo, Ghislain W. Fotso, O ğuzhan Karaosmanoğlu, Bonaventure T. Ngadjui, Felix Keumedjio, Samuel O. Yeboah, Kerstin Andrae-Marobela and Hülya Sivas Tags: Research article Source Type: research