Filtered By:
Therapy: Stem Cell Therapy
This page shows you your search results in order of relevance.
Order by Relevance | Date
Total 200961 results found since Jan 2013.
Beliefs about hydroxyurea in youth with sickle cell disease
Conclusions Beliefs about hydroxyurea correlated with HRQOL scores and adherence levels. Addressing patients’ concern about hydroxyurea and medications overall as well as routine assessment of adherence and beliefs could help to overcome adherence barriers.
Source: Hematology Oncology and Stem Cell Therapy - February 3, 2018 Category: Cancer & Oncology Source Type: research
Pragmatic pluralism: Mutual tolerance of contested understandings between orthodox and alternative practitioners in autologous stem cell transplantation
AbstractHigh-dose chemotherapy and autologous stem cell transplantation (ASCT) is used to treat some advanced malignancies. It is a traumatic procedure, with a high complication rate and significant mortality. ASCT patients and their carers draw on many sources of information as they seek to understand the procedure and its consequences. Some seek information from beyond orthodox medicine. Alternative beliefs and practices may conflict with conventional understanding of the theory and practice of ASCT, and ‘contested understandings’ might interfere with patient adherence to the strict and demanding protocols required f...
Source: Journal of Bioethical Inquiry - April 1, 2022 Category: Medical Ethics Source Type: research
Mucopolysaccharidosis I; Parental beliefs about the impact of disease on the quality of life of their children
Hematopoietic stem cell transplants, alongside enzyme replacement therapy and good multi-disciplinary care, have dramatically improved the life expectancy in children with Mucopolysaccharidosis (MPS) I, with b...
Source: Orphanet Journal of Rare Diseases - July 12, 2016 Category: Internal Medicine Authors: A. Soni-Jaiswal, J. Mercer, S. A. Jones, I. A. Bruce and P. Callery Source Type: research
Grafted Subventricular Zone Neural Stem Cells Display Robust Engraftment and Similar Differentiation Properties and Form New Neurogenic Niches in the Young and Aged Hippocampus
We examined the engraftment and differentiation of alkaline phosphatase-positive NSCs expanded from the postnatal subventricular zone (SVZ), 3 months after grafting into the intact young or aged rat hippocampus. Graft-derived cells engrafted robustly into both young and aged hippocampi. Although most graft-derived cells pervasively migrated into different hippocampal layers, the graft cores endured and contained graft-derived neurons expressing neuron-specific nuclear antigen (NeuN) and -amino butyric acid in both groups. A fraction of migrated graft-derived cells in the neurogenic subgranular zone-granule cell layer also ...
Source: Stem Cells Translational Medicine - August 23, 2016 Category: Stem Cells Authors: Shetty, A. K., Hattiangady, B. Tags: Neural/Progenitor Stem Cells, Tissue-Specific Progenitor and Stem Cells Source Type: research
Correlation of F-18FDG uptake and breast cancer stem cells in taxol resistant human breast cancer cell
Conclusions Various chemotherapeutic agents were commonly used in the breast cancer treatment. Some breast cancers were still relapse or metastasize after chemotherapy due to cancer stem cells. Paclitaxel resistance cells (MCF7-TR) had characteristic of cancer stem cells and higher FDG uptake. These might have implications for interpretation of intra-tumoral FDG uptake in paclitaxel-resistance breast cancer.
Source: Journal of Nuclear Medicine - May 23, 2016 Category: Nuclear Medicine Authors: Kim, M. H., Kim, K. I., Lee, T. S., Ryu, P. Y., Lee, Y. J., Kim, S. J., Kang, J. H. Tags: Oncology - Small Molecules, Peptides and Antibodies for Detection and Staging Source Type: research
Janssen to Highlight Latest Scientific Advances in Hematologic Diseases at ASH 2022 with Clinical and Real-World Data Across Innovative Pipeline and Distinguished Portfolio
RARITAN, N.J., November 3, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson are committed to redefining treatment outcomes in the hematology setting and today announced that abstracts from more than 50 company-sponsored studies, plus more than 20 investigator-initiated studies, will be presented at the American Society of Hematology (ASH) Annual Meeting in New Orleans from December 10-13, 2022. Janssen’s commitment to advancing an innovative portfolio of therapies for healthcare professionals and patients is evidenced through more than 70 presentations that span clinical studies and r...
Source: Johnson and Johnson - November 3, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Telocytes and putative stem cells in ageing human heart
Abstract
Tradition considers that mammalian heart consists of about 70% non‐myocytes (interstitial cells) and 30% cardiomyocytes (CMs). Anyway, the presence of telocytes (TCs) has been overlooked, since they were described in 2010 (visit www.telocytes.com). Also, the number of cardiac stem cells (CSCs) has not accurately estimated in humans during ageing. We used electron microscopy to identify and estimate the number of cells in human atrial myocardium (appendages). Three age‐related groups were studied: newborns (17 days–1 year), children (6–17 years) and adults (34–60 years). Morphometry was performed on l...
Source: Journal of Cellular and Molecular Medicine - December 1, 2014 Category: Molecular Biology Authors: Laurentiu M. Popescu, Antoanela Curici, Enshi Wang, Hao Zhang, Shengshou Hu, Mihaela Gherghiceanu Tags: Original Article Source Type: research
Evidence and Access to Biomedical Interventions: The Case of Stem Cell Treatments
The controversy over patients’ access to stem cell interventions is familiar to scholars of the drug regulatory system and the politics of evidence-based medicine. What counts as evidence of a biomedical intervention's safety and effectiveness? Who should define and assess safety and effectiveness, and how? In the first section of the paper we describe the types of stem cells that may be therapeutically effective. We then describe how the US Food and Drug Administration asserted regulatory authority over certain stem cell interventions and the legal challenge to the agency's actions. Next, we place the debate about p...
Source: Journal of Health Politics, Policy and Law - September 11, 2016 Category: Health Management Authors: Maschke, K. J., Gusmano, M. K. Tags: Health Policy & Education, Political Science, General, Public Policy Articles Source Type: research
Developing a Policy for Use of Medicinal and Non Medicinal Marijuana in Stem Cell Transplant Patients
Topic Significance& Study Purpose/Background/Rationale: Recent years have brought about a rapid change in the approach that many states take towards the utilization of medical and non-medical marijuana. It is currently being used in multiple formulations (i.e. oils, edibles, topical) to manage a wide range of symptoms. Despite the more widespread use of medical marijuana, there are many misconceptions from the patients, family members and medical providers about its use. Given that there are potential added risks associated with using cannabinoids in stem cell transplant (SCT) patients, our center decided to embark on a pr...
Source: Biology of Blood and Marrow Transplantation - February 1, 2018 Category: Hematology Authors: Chris Rimkus, Rachel A. Didion Source Type: research
Tracking of autologous adipose tissue-derived mesenchymal stromal cells with in vivo magnetic resonance imaging and histology after intralesional treatment of artificial equine tendon lesions - a pilot study
Adipose tissue-derived mesenchymal stromal cells (AT-MSCs) are frequently used to treat equine tendinopathies. Up to now, knowledge about the fate of autologous AT-MSCs after intralesional injection into equin...
Source: Stem Cell Research and Therapy - February 1, 2016 Category: Stem Cells Authors: Florian Geburek, Kathrin Mundle, Sabine Conrad, Maren Hellige, Ulrich Walliser, Hans T. M. van Schie, René van Weeren, Thomas Skutella and Peter M. Stadler Source Type: research
Human–animal chimeras: ethical issues about farming chimeric animals bearing human organs
Recent advances in stem cells and gene engineering have paved the way for the generation of interspecies chimeras, such as animals bearing an organ from another species. The production of a rat pancreas by a m...
Source: Stem Cell Research and Therapy - June 29, 2016 Category: Stem Cells Authors: Rodolphe Bourret, Eric Martinez, François Vialla, Chloé Giquel, Aurélie Thonnat-Marin and John De Vos Source Type: research
A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation
Nature Cell Biology 19, 1012 (2017).
doi:10.1038/ncb3602
Authors: Clea Bárcena & Carlos López-Otín
Induced pluripotent stem cells derived from aged donors (A-iPSCs) usually show genomic instability that affects their utility and raises concerns about their safety. Now, a study highlights the importance of ZSCAN10-dependent recovery of glutathione–ROS homeostasis in counteracting the genomic defects in A-iPSCs.
Source: Nature Cell Biology - August 31, 2017 Category: Cytology Authors: Clea B á rcena Carlos L ó pez-Ot í n Tags: News and Views Source Type: research
Adipose-derived stem cell research, worry and hope
In the wake of call for retractions of papers from Harvard University heart stem cell research lab, the public concerns had been raised about stem cell researches, including adipose-derived stem cells (ADSCs).
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - December 15, 2018 Category: Cosmetic Surgery Authors: Jiaqi Liu Tags: Correspondence and Communications Source Type: research
