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Vaccination: Whooping Cough (Pertussis) Vaccine
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Knowledge, Attitudes and Perceptions About Routine Childhood Vaccinations Among Jewish Ultra-Orthodox Mothers Residing in Communities with Low Vaccination Coverage in the Jerusalem District
Conclusion Investigating maternal knowledge and attitudes on childhood vaccinations provides insights that may assist in planning tailored intervention programs aimed to increase both vaccination coverage and timeliness.
Source: Maternal and Child Health Journal - January 15, 2017 Category: Health Management Source Type: research
“One of the greatest medical success stories:” Physicians and nurses’ small stories about vaccine knowledge and anxieties
Publication date: Available online 20 November 2017 Source:Social Science & Medicine Author(s): Terra Manca In recent years, the Canadian province of Alberta experienced outbreaks of measles, mumps, pertussis, and influenza. Even so, the dominant cultural narrative maintains that vaccines are safe, effective, and necessary to maintain population health. Many vaccine supporters have expressed anxieties that stories that contradict this narrative have lowered herd immunity levels because they frighten the public into avoiding vaccination. As such, vaccine policies often emphasize educating parents and the public abo...
Source: Social Science and Medicine - November 21, 2017 Category: Psychiatry & Psychology Source Type: research
Immunogenity and antibodies persistance of diphteria-tetanus-acellular pertussis vaccination in adolescent and adults: a sistematic review of the literature showed different response to the available vaccines
Discussion and conclusion: We found a limited number of good-quality RCTs investigating our object. The five component vaccines, although containing a lower dosage of antigen, are found to be more effective than one components vaccines for prevention. Evidences support the use of 5-components vaccines for booster sessions in adolescence and adulthood.Introduction: In industrialized countries, routine use of pertussis vaccines has shifted the burden of pertussis disease from children to infants, adolescents and adults, leading to the necessity of booster doses.Materials and methods:We prepared the review following the Prefe...
Source: Journal of Preventive Medicine and Hygiene - January 14, 2021 Category: International Medicine & Public Health Authors: Raffaele Squeri, Cristina Genovese Source Type: research
World leaders must fund a Covid-19 vaccine plan before it's too late for millions | Gro Harlem Brundtland and Elizabeth Cousens
This week ’s Global Vaccine Summit comes at a crucial point in history. Governments must not miss their chance to save livesCoronavirus – latest updatesSee all our coronavirus coverageGro Harlem Brundtland is former director-general of the World Health OrganizationElizabeth Cousens is president of the UN FoundationGoogle any list of the most successful public health interventions of this century or the last, and vaccines will be at the very top. Infectious diseases such as smallpox, measles, diphtheria and pertussis (whooping cough) were once prevalent and killed indiscriminately. Smallpox is now eradicated, polio is o...
Source: Guardian Unlimited Science - June 4, 2020 Category: Science Authors: Gro Harlem Brundtland and Elizabeth Cousens Tags: Vaccines and immunisation Coronavirus outbreak Infectious diseases Medical research Science World Health Organization Polio World news Source Type: news
Barriers and facilitators regarding influenza and pertussis maternal vaccination uptake: A multi-center survey of pregnant women in Italy
ConclusionsLack of immunization advice by health-care providers and safety concerns were the main vaccination barriers against influenza and pertussis, among surveyed pregnant women. Vaccine delivery in the antenatal care setting could lead to increase of vaccine acceptance among pregnant women.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - February 6, 2020 Category: OBGYN Source Type: research
An evaluation of strategies to achieve greater than 90% coverage of maternal influenza and pertussis vaccines including an economic evaluation
Maternal immunisation is an essential public health intervention aimed at improving the health outcomes for pregnant women and providing protection to the newborn. Despite international recommendations, safety...
Source: BMC Pregnancy and Childbirth - November 15, 2021 Category: OBGYN Authors: Michelle L. Giles, Kong Khai, Sushena Krishnaswamy, Karen Bellamy, Margaret Angliss, Christopher Smith, Olivia Fay, Paul Paddle and Beverley Vollenhoven Tags: Research Source Type: research
Acceptance of vaccination against pertussis, COVID-19 and influenza during pregnancy: a cross-sectional study
This study aims to assess the uptake of maternal pertussis and COVID-19 vaccination and the intention towards accepting the maternal influenza vaccination. Insights into different socio-demographic factors rel...
Source: BMC Pregnancy and Childbirth - March 30, 2023 Category: OBGYN Authors: Veja Widdershoven, Rianne P. Reijs, Annika Eskes, Amanja Verhaegh-Haasnoot and Christian J.P.A. Hoebe Tags: Research Source Type: research
South Africa: Measles and Whooping Cough Outbreaks in South Africa - a Sign of Low Vaccination Coverage, Experts Warn
[The Conversation Africa] The concentrated global effort to use vaccination as a public health intervention began in 1974. Since then, vaccination has changed our lives. Worldwide, in the decades 2000-2020, childhood vaccination led to the reduction of deaths in children under 5 by 50% to 5.4 million deaths per year. Vaccination currently averts more than 5 million deaths each year worldwide. These are deaths that would have been caused by measles, whooping cough, tetanus, polio, diphtheria, pneumonia, rotavirus diarrhoea, and othe
Source: AllAfrica News: Health and Medicine - June 15, 2023 Category: African Health Tags: Health and Medicine South Africa Southern Africa Source Type: news
Current developments and trends in childhood immunization
Abstract: In this paper we highlight several instances in which there is potential for novel utilization in the near future of relatively recently licenced vaccines, vaccines approaching licensure or vaccines already in established use. Specifically we discuss the potential for universal seasonal influenza immunization and the arrival of live attenuated intranasal vaccine which was licenced for use in children aged 2–17 years in Europe in 2010, the potential use of live oral rotavirus vaccines for infants, two of which have been available in Europe since 2006, pertussis, which despite availability and widespread use thro...
Source: Paediatrics and Child Health - March 1, 2013 Category: Pediatrics Authors: Valtyr S. Thors, Robin D. Marlow, Adam Finn Tags: Symposium: Immunity and Infection Source Type: research
Safety and Immunogenicity of Tetanus, Diphtheria, and Acellular Pertussis Immunization During Pregnancy in Mothers and Infants: A Randomized Clinical Trial
ABSTRACT: Pertussis has reemerged in the United States despite high childhood immunization rates. To protect young infants, tetanus, diphtheria, and acellular pertussis vaccine (Tdap) has been used in postpartum women and close contacts of infants, in previously Tdap unimmunized pregnant women, as well as in all pregnant women during every pregnancy, regardless of prior Tdap immunization. This randomized, double-blind, placebo-controlled clinical trial was undertaken to evaluate the safety and immunogenicity of Tdap vaccine administered to women in the third trimester of pregnancy.
Healthy parturients aged 18 to 45 years a...
Source: Obstetrical and Gynecological Survey - September 1, 2014 Category: OBGYN Tags: Obstetrics: Prenatal and Preconception Care Source Type: research
Evaluation of the Association of Maternal Pertussis Vaccination With Obstetric Events and Birth Outcomes
ABSTRACT: Bordetella pertussis is a highly contagious respiratory pathogen, with infants at highest risk for severe infections. In 2005, the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) was licensed for use in nonpregnant adolescents and adults. Postpartum administration of Tdap to parents and other caregivers was encouraged to prevent the transmission of pertussis to newborns. In 2011, the Advisory Committee on Immunization Practices recommended that Tdap be administered at 20 weeks or greater to women who had not been previously vaccinated. In 2012, the committee recommended that Tdap...
Source: Obstetrical and Gynecological Survey - March 1, 2015 Category: OBGYN Tags: Obstetrics: Preconception and Prenatal Care Source Type: research
Association of TDAP Vaccination With Acute Events and Adverse Birth Outcomes Among Pregnant Women With Prior Tetanus-Containing Immunizations
Obstet Gynecol Surv 2016;71(1):1–2
Neonates and infants are at increased risk of pertussis-related hospitalization and death. In 2012, the Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices recommended tetanus, diphtheria, and acellular pertussis (TDAP) vaccination for all pregnant women during each pregnancy irrespective of prior immunization status.
Source: Obstetrical and Gynecological Survey - January 1, 2016 Category: OBGYN Tags: Obstetrics: Preconception and Prenatal Care Source Type: research
Travel Characteristics and Pretravel Health Care Among Pregnant or Breastfeeding U.S. Women Preparing for International Travel.
CONCLUSION: Most pregnant and breastfeeding travelers seen for pretravel health consultations traveled to destinations with high risk for vector-borne or other travel-related diseases. Destination-specific preventive interventions were frequently underused.
PMID: 29112671 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - November 3, 2017 Category: OBGYN Authors: Hagmann SHF, Rao SR, LaRocque RC, Erskine S, Jentes ES, Walker AT, Barnett ED, Chen LH, Hamer DH, Ryan ET, Global TravEpiNet Consortium and the Boston Area Travel Medicine Network Tags: Obstet Gynecol Source Type: research
Characterization of Individual Human Antibodies That Bind Pertussis Toxin Stimulated by Acellular Immunization Microbial Immunity and Vaccines
Despite high vaccination rates, the incidence of whooping cough has steadily been increasing in developing countries for several decades. The current acellular pertussis (aP) vaccines all include the major protective antigen pertussis toxin (PTx) and are safer, but they appear to be less protective than infection or older, whole-cell vaccines. To better understand the attributes of individual antibodies stimulated by aP, we isolated plasmablast clones recognizing PTx after booster immunization of two donors. Five unique antibody sequences recognizing native PTx were recovered and expressed as recombinant human IgG1 antibod...
Source: Infection and Immunity - May 22, 2018 Category: Infectious Diseases Authors: Acquaye-Seedah, E., Reczek, E. E., Russell, H. H., DiVenere, A. M., Sandman, S. O., Collins, J. H., Stein, C. A., Whitehead, T. A., Maynard, J. A. Tags: Microbial Immunity and Vaccines Source Type: research
The Adjuvant Bordetella Colonization Factor A Attenuates Alum-Induced Th2 Responses and Enhances Bordetella pertussis Clearance from Mouse Lungs Microbial Immunity and Vaccines
The reemergence of pertussis or whooping cough in several countries highlights the need for better vaccines. Acellular pertussis vaccines (aPV) contain alum as the adjuvant and elicit Th2-biased immune responses that are less effective in protecting against infection than the reactogenic whole-cell pertussis vaccines (wPV), which elicit primarily a Th1/Th17 response. An important goal for the field is to devise aPV that will induce immune responses similar to those of wPV. We show that Bordetella colonization factor A (BcfA), an outer membrane protein from Bordetella bronchiseptica, has strong adjuvant function and elicits...
Source: Infection and Immunity - May 22, 2018 Category: Infectious Diseases Authors: Jennings-Gee, J., Quataert, S., Ganguly, T., D'Agostino, R., Deora, R., Dubey, P. Tags: Microbial Immunity and Vaccines Source Type: research
