• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country
• Remove Filter

Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients
ConclusionTh22, Th17, Th1, and Th2 subsets may play an essential role in BC patients. Th22, Th17, Th1, and Th2 cells may have potential significance to be used as clinical markers in BC patients with different molecular classification. Th22 cells may have potential value in BC patients ’ outcomes prediction, providing clinical value.
Source: Thoracic Cancer - September 22, 2023 Category: Cancer & Oncology Authors: Zhiguo Peng, Xinyue Dong, Miao He, Yajing Zhao, Yujia Liu, Mo Li, Guosheng Li, Xiuwen Wang, Li Li, Yu Hu Tags: ORIGINAL ARTICLE Source Type: research

Correction: α-Catenin acetylation is essential for its stability and blocks its tumor suppressor effects in breast cancer through Yap1
Cancer Gene Therapy, Published online: 22 September 2023; doi:10.1038/s41417-023-00668-1Correction: α-Catenin acetylation is essential for its stability and blocks its tumor suppressor effects in breast cancer through Yap1
Source: Cancer Gene Therapy - September 22, 2023 Category: Cancer & Oncology Authors: Yuxi Yang Shujing Li Yulin Li Linlin Lv Dongman Ye Jie Kang Tao Yu Yaming Wang Huijian Wu Source Type: research

Elevated profiles of peripheral Th22, Th17, Th2 cells, and decreased percentage of Th1 cells in breast cancer patients
CONCLUSION: Th22, Th17, Th1, and Th2 subsets may play an essential role in BC patients. Th22, Th17, Th1, and Th2 cells may have potential significance to be used as clinical markers in BC patients with different molecular classification. Th22 cells may have potential value in BC patients' outcomes prediction, providing clinical value.PMID:37732365 | DOI:10.1111/1759-7714.15119
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Zhiguo Peng Xinyue Dong Miao He Yajing Zhao Yujia Liu Mo Li Guosheng Li Xiuwen Wang Li Li Yu Hu Source Type: research

Potential impact of HercepTest ™ mAb PharmDx (Dako Omnis) (ge001) in breast cancer diagnosis
Pol J Pathol. 2023;74(2):82-88. doi: 10.5114/pjp.2023.129352.ABSTRACTThe HER2 gene is a biomarker for breast cancer prognosis and treatment. Overexpression of HER2 protein determined by immunohistochemistry (IHC) or amplification of the HER2 gene determined by fluorescence in situ hybridization (FISH) is a condition for qualifying patients for anti-HER2 therapy. Due to the high toxicity of anti-HER2 treatment, proper patient selection is essential. In our study we compared 40 cases with IHC staining of HER2 antibody determined by Ventana PATHWAY anti-HER2/neu antibody (4B5) as HER2 2+ with the new antibody (HercepTest™ m...
Source: Polish Journal of Pathology - September 20, 2023 Category: Pathology Authors: Andrzej Marsza łek Agata Kubicka Inga Jagie łło Anna Malicka-Durczak Source Type: research

ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway
In conclusion, this study uncovers the role of ZNF746 in promoting M2 macrophage polarisation and suggests that ZNF746 may be a promising therapeutic target for limiting BC progression.PMID:37730102 | DOI:10.1016/j.cellsig.2023.110892
Source: Cellular Signalling - September 20, 2023 Category: Cytology Authors: Lu Liu Wen-Yue Zhao Xin-Yu Zheng Source Type: research

Synthesis and antitumor activity of bagasse xylan derivatives modified by graft-esterification and cross-linking
Int J Biol Macromol. 2023 Sep 18:126867. doi: 10.1016/j.ijbiomac.2023.126867. Online ahead of print.ABSTRACTA crucial aspect in achieving sustainable development of biomass materials is the modification of renewable polysaccharides to create various high-value functional materials. In this paper, bagasse xylan (BX) was used as a raw material to introduce benzyl methacrylate (BMA) through graft copolymerization reaction to generate the intermediate product BX-g-BMA. Subsequently, the target product (CA-BX-g-BMA) was synthesized by catalytic esterification of BX-g-BMA with citric acid (CA) in AmimCl ionic liquid. Meanwhile, ...
Source: International Journal of Biological Macromolecules - September 20, 2023 Category: Biochemistry Authors: Bin Zhao Heping Li Kexin Tian Yue Su Zhiming Zou Source Type: research

ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway
In conclusion, this study uncovers the role of ZNF746 in promoting M2 macrophage polarisation and suggests that ZNF746 may be a promising therapeutic target for limiting BC progression.PMID:37730102 | DOI:10.1016/j.cellsig.2023.110892
Source: Cellular Signalling - September 20, 2023 Category: Cytology Authors: Lu Liu Wen-Yue Zhao Xin-Yu Zheng Source Type: research

The effectiveness of exercise on the symptoms in breast cancer patients undergoing adjuvant treatment: an umbrella review of systematic reviews and meta-analyses
ConclusionsResearch is still needed to confirm the majority of studies’ recommendations for exercise during adjuvant treatment for breast cancer patients, as it is crucial for managing symptoms in the rehabilitation process. To increase the efficiency of exercise in symptom management, future studies may focus more on the application of bridge symptoms, symptom networks, and ecological instantaneous assessment.
Source: Frontiers in Oncology - September 20, 2023 Category: Cancer & Oncology Source Type: research

The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer
Res Sq. 2023 Sep 8:rs.3.rs-3266720. doi: 10.21203/rs.3.rs-3266720/v1. Preprint.ABSTRACTThe alternative splicing of PML precursor mRNA gives rise to various PML isoforms, yet their expression profile in breast cancer cells remains uncharted. We discovered that PML1 is the most abundant isoform in all breast cancer subtypes, and its expression is associated with unfavorable prognosis in estrogen receptor-positive (ER+) breast cancers. PML depletion reduces cell proliferation, invasion, and stemness, while heterologous PML1 expression augments these processes and fuels tumor growth and resistance to fulvestrant, an FDA-approv...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Hung-Ying Kao Chun-Peng Pai Han Wang Neel Agarwal Joshua Adams Zhenghao Liu Darcie Seachrist Ruth Keri William Schiemann Source Type: research

An updated systemic review and meta-analysis on human papillomavirus in breast carcinogenesis
CONCLUSION: Current study provides a global estimate of HPV prevalence in BC patients and demonstrates a significant association between this virus and BC etiology. Nevertheless, we recommend further investigation into the underlying mechanism is essential to validate this hypothesis.PMID:37711194 | PMC:PMC10498127 | DOI:10.3389/fonc.2023.1219161
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Usman Ayub Awan Aamer Ali Khattak Noman Ahmed Xingyi Guo Sohail Akhtar Shehrish Kamran Zhao Yongjing Jianbo Liu Suliman Khan Source Type: research

Quality evaluation of health information about breast cancer treatment found on WeChat public accounts
ConclusionsThe quality of the articles on breast cancer treatment health information in WPAs was moderate. WPA producers should focus on improving the reliability of information and providing more details on treatment options, to assist patients in making optimal decisions during treatment.
Source: Archives of Public Health - September 15, 2023 Category: International Medicine & Public Health Source Type: research

Alkaloids as Additional Weapons in the Fight against Breast Cancer: A review
This study also includes an overview of synthesized analogues and pharmacological characteristics that will be beneficial to scientists working on alkaloids for medicinal purposes. In a recent survey of the literature, alkaloids are an important component of plant-derived antitumor medicines that hold great potential for the future development of cancer therapy and preventive therapies. We have also discussed structural analysis relationship (SAR) studies. Moreover, it covers clinical trial medications and FDA-approved medicines from the last five years that will be useful in further research.PMID:37702171 | DOI:10.2174/09...
Source: Current Medicinal Chemistry - September 13, 2023 Category: Chemistry Authors: None Chahat Keshav Taruneshwar Jha Rohit Bhatia Pooja A Chawla Source Type: research

Intrathecal Catheter for Chemotherapy in Leptomeningeal Carcinomatosis From HER2-Negative Metastatic Breast Cancer
CONCLUSION: Infusing chemotherapy using an implanted catheter is an efficient option for managing IT chemotherapy with a good tolerance profile. Patient-reported outcomes for the evaluation of IT chemotherapy toxicity are currently being developed.PMID:37704384 | DOI:10.4048/jbc.2023.26.e40
Source: Journal of Breast Cancer - September 13, 2023 Category: Cancer & Oncology Authors: Denis Dupoiron Lila Autier Nathalie Lebrec Val érie Seegers Caroline Folliard Anne Patsouris Mario Campone Paule Augereau Source Type: research

Alkaloids as Additional Weapons in the Fight against Breast Cancer: A review
This study also includes an overview of synthesized analogues and pharmacological characteristics that will be beneficial to scientists working on alkaloids for medicinal purposes. In a recent survey of the literature, alkaloids are an important component of plant-derived antitumor medicines that hold great potential for the future development of cancer therapy and preventive therapies. We have also discussed structural analysis relationship (SAR) studies. Moreover, it covers clinical trial medications and FDA-approved medicines from the last five years that will be useful in further research.PMID:37702171 | DOI:10.2174/09...
Source: Current Medicinal Chemistry - September 13, 2023 Category: Chemistry Authors: None Chahat Keshav Taruneshwar Jha Rohit Bhatia Pooja A Chawla Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20