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Source: Psychopharmacology Bulletin

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Total 5503 results found since Jan 2013.

Probable Olanzapine-Related Idiopathic Intracranial Hypertension in an Adolescent With First-Episode Psychosis
Psychopharmacol Bull. 2023 Aug 11;53(3):69-72.ABSTRACTPseudotumor cerebri or idiopathic intracranial hypertension (IIH) secondary to psychotropic drugs is a very rare occurrence. Lithium is typically the culprit agent. Here, authors report on an interesting case of an adolescent with early-onset schizophrenia that develops a reversible IIH putatively related to olanzapine-induced weight gain. This is followed by discussion of purported pharmacodynamic mechanisms and brief review of literature. Clinicians should be cognizant to this serious complication given the propensity of the majority of atypical antipsychotics to indu...
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Camellia Naguy Sanaa Sabir Source Type: research

Effects of Venlafaxine on the Size of Brain and Expression of < em > SHANK3 < /em > , < em > TUBB5 < /em > and < em > DDC < /em > Genes in BALB/c Mice
CONCLUSIONS: These results provide evidence that use of venlafaxine during pregnancy may affect the brain development in mice and altered the expression of SHANK3 and TUBB5 genes in brain tissue.PMID:37601086 | PMC:PMC10434312
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Ramesh Ranjbar Zahra Zamanzadeh Ali Mohammad Ahadi Source Type: research

Association Between Symptom Severity and Medication Adherence in Adolescents with Bipolar Disorder Demonstrating Suboptimal Adherence
CONCLUSION: Adherence levels varied widely in AYA with BD. Adherence monitoring increased adherence by approximately 4.5%, and use of electronic pill monitoring identified a greater proportion of missed medication vs. self-report. BD symptoms may not consistently identify AYA with adherence challenges.PMID:37601085 | PMC:PMC10434309
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Martha Sajatovic Jennifer B Levin Avani Modi Molly McVoy Larry F Forthun Raechel Cooley Jessica Black Carla Conroy Kaylee Sarna Farren B Briggs Melissa DelBello Source Type: research

Cannabis Pen-Induced Psychosisin a First-Time Adolescent User
Psychopharmacol Bull. 2023 Aug 11;53(3):61-65.ABSTRACTCannabis is a widely used illicit substance that is historically consumed via smoking, but alternative methods of cannabis consumption have been growing in popularity over the past several decades. One such modality is vaporization, which can appeal specifically to adolescent consumers given these pen devices' ease of concealment, lack of characteristic odor, and marketability. Cannabis products designed for vaping often have higher concentrations of the psychoactive component of cannabis, tetrahydrocannabinol (THC), when compared with traditional cannabis leaf smoking....
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Patrick J Beck Abhishek Reddy Source Type: research

Transcranial Magnetic Stimulation (TMS) for Major Depressive Disorder-Modus Operandi!
CONCLUSION: TMS produces a range of physiological changes. It is unclear which of these underpin its antidepressant. It is likely more than one work synergistically to this end-almost certainly the capacity to correct MDD induced FC abnormalities makes a strong antidepressant contribution.PMID:37601083 | PMC:PMC10434311
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Saxby Pridmore Yvonne Turnier-Shea Marzena Rybak Ahmed Naguy Source Type: research

On the Origins of MAOI Misconceptions: Reaffirming their Role in Melancholic Depression
Psychopharmacol Bull. 2023 Aug 11;53(3):35-54.ABSTRACTThe first monoamine oxidase inhibitors (MAOIs) used for the treatment of depression in the 1950-60s were credited with treating severe melancholic depression (MeD) successfully and greatly reducing the need for electroconvulsive therapy (ECT). Following the hiatus caused by the then ill-understood cheese reaction, MAOI use was relegated to atypical and treatment-resistant depressions only, based on data from insufficiently probing research studies suggesting their comparatively lesser effectiveness in MeD. The siren attraction of new 'better' drugs with different mechan...
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Vincent Van den Eynde Gordon Parker Henricus G Ruh é Tom K Birkenh äger Lila Godet Edward Shorter Peter Kenneth Gillman Source Type: research

Takotsubo Cardiomyopathy Related to Duloxetine-Atomoxetine Combination in an Adolescent with ADHD and Comorbid GAD
Psychopharmacol Bull. 2023 Aug 11;53(3):66-68.ABSTRACTAuthors report on an interesting case of a teenager with attention-deficit/hyperactivity disorder and comorbid generalized anxiety disorder, who developed takotsubo cardiomyopathy subsequent to pharmacokinetic and pharmacodynamic interactions between atomoxetine, a selective norepinephrine reuptake inhibitor, and the antidepressant duloxetine. Clinicians should be mindful of the potential for cardiovascular adverse effects when prescribing agents that target noradrenergic receptors.PMID:37601081 | PMC:PMC10434308
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Bibi Alamiri Source Type: research

Probable Olanzapine-Related Idiopathic Intracranial Hypertension in an Adolescent With First-Episode Psychosis
Psychopharmacol Bull. 2023 Aug 11;53(3):69-72.ABSTRACTPseudotumor cerebri or idiopathic intracranial hypertension (IIH) secondary to psychotropic drugs is a very rare occurrence. Lithium is typically the culprit agent. Here, authors report on an interesting case of an adolescent with early-onset schizophrenia that develops a reversible IIH putatively related to olanzapine-induced weight gain. This is followed by discussion of purported pharmacodynamic mechanisms and brief review of literature. Clinicians should be cognizant to this serious complication given the propensity of the majority of atypical antipsychotics to indu...
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Camellia Naguy Sanaa Sabir Source Type: research

Effects of Venlafaxine on the Size of Brain and Expression of < em > SHANK3 < /em > , < em > TUBB5 < /em > and < em > DDC < /em > Genes in BALB/c Mice
CONCLUSIONS: These results provide evidence that use of venlafaxine during pregnancy may affect the brain development in mice and altered the expression of SHANK3 and TUBB5 genes in brain tissue.PMID:37601086 | PMC:PMC10434312
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Ramesh Ranjbar Zahra Zamanzadeh Ali Mohammad Ahadi Source Type: research

Association Between Symptom Severity and Medication Adherence in Adolescents with Bipolar Disorder Demonstrating Suboptimal Adherence
CONCLUSION: Adherence levels varied widely in AYA with BD. Adherence monitoring increased adherence by approximately 4.5%, and use of electronic pill monitoring identified a greater proportion of missed medication vs. self-report. BD symptoms may not consistently identify AYA with adherence challenges.PMID:37601085 | PMC:PMC10434309
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Martha Sajatovic Jennifer B Levin Avani Modi Molly McVoy Larry F Forthun Raechel Cooley Jessica Black Carla Conroy Kaylee Sarna Farren B Briggs Melissa DelBello Source Type: research

Cannabis Pen-Induced Psychosisin a First-Time Adolescent User
Psychopharmacol Bull. 2023 Aug 11;53(3):61-65.ABSTRACTCannabis is a widely used illicit substance that is historically consumed via smoking, but alternative methods of cannabis consumption have been growing in popularity over the past several decades. One such modality is vaporization, which can appeal specifically to adolescent consumers given these pen devices' ease of concealment, lack of characteristic odor, and marketability. Cannabis products designed for vaping often have higher concentrations of the psychoactive component of cannabis, tetrahydrocannabinol (THC), when compared with traditional cannabis leaf smoking....
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Patrick J Beck Abhishek Reddy Source Type: research

Transcranial Magnetic Stimulation (TMS) for Major Depressive Disorder-Modus Operandi!
CONCLUSION: TMS produces a range of physiological changes. It is unclear which of these underpin its antidepressant. It is likely more than one work synergistically to this end-almost certainly the capacity to correct MDD induced FC abnormalities makes a strong antidepressant contribution.PMID:37601083 | PMC:PMC10434311
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Saxby Pridmore Yvonne Turnier-Shea Marzena Rybak Ahmed Naguy Source Type: research

On the Origins of MAOI Misconceptions: Reaffirming their Role in Melancholic Depression
Psychopharmacol Bull. 2023 Aug 11;53(3):35-54.ABSTRACTThe first monoamine oxidase inhibitors (MAOIs) used for the treatment of depression in the 1950-60s were credited with treating severe melancholic depression (MeD) successfully and greatly reducing the need for electroconvulsive therapy (ECT). Following the hiatus caused by the then ill-understood cheese reaction, MAOI use was relegated to atypical and treatment-resistant depressions only, based on data from insufficiently probing research studies suggesting their comparatively lesser effectiveness in MeD. The siren attraction of new 'better' drugs with different mechan...
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Vincent Van den Eynde Gordon Parker Henricus G Ruh é Tom K Birkenh äger Lila Godet Edward Shorter Peter Kenneth Gillman Source Type: research

Takotsubo Cardiomyopathy Related to Duloxetine-Atomoxetine Combination in an Adolescent with ADHD and Comorbid GAD
Psychopharmacol Bull. 2023 Aug 11;53(3):66-68.ABSTRACTAuthors report on an interesting case of a teenager with attention-deficit/hyperactivity disorder and comorbid generalized anxiety disorder, who developed takotsubo cardiomyopathy subsequent to pharmacokinetic and pharmacodynamic interactions between atomoxetine, a selective norepinephrine reuptake inhibitor, and the antidepressant duloxetine. Clinicians should be mindful of the potential for cardiovascular adverse effects when prescribing agents that target noradrenergic receptors.PMID:37601081 | PMC:PMC10434308
Source: Psychopharmacology Bulletin - August 21, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Bibi Alamiri Source Type: research