Filtered By:
Condition: Gastrointestinal Polyps
This page shows you your search results in order of date.
Order by Relevance | Date
Total 6 results found since Jan 2013.
Six Ways to Lower Your Risk for Colon Cancer
By Stacy Simon Colon cancer is one of the more common cancers in the US. About 1 in 20 Americans will develop colon cancer at some point during their lifetime. But there are things you can do to help lower your colon cancer risk. Here are 6 ways to help protect your colon health. Get screened for colon cancer. Screenings are tests that look for cancer before signs and symptoms develop. Colon screenings can often find growths called polyps that can be removed before they turn into cancer. These tests also can find colon cancer earlier, when treatments are more likely to be successful. The American Cancer Society recommend...
Source: American Cancer Society :: News and Features - March 7, 2016 Category: Cancer & Oncology Tags: Colon/Rectum Cancer Source Type: news
Signs and Symptoms of Colon Cancer
By Stacy Simon Many of the symptoms of colon cancer can also be caused by something that isn’t cancer, such as infection, hemorrhoids, irritable bowel syndrome, or inflammatory bowel disease. In most cases, people who have these symptoms do not have cancer. Still, if you have any of these problems, it is a sign that you should go to the doctor so the cause can be found and treated, if needed:A change in bowel habits, such as diarrhea, constipation, or narrowing of the stool, that lasts for more than a few daysA feeling that you need to have a bowel movement that is not relieved by doing soRectal bleedingDark stools, ...
Source: American Cancer Society :: News and Features - February 29, 2016 Category: Cancer & Oncology Tags: Colon/Rectum Cancer Prevention/Early Detection Source Type: news
Abstract 2745: Exome sequencing analysis of 41 patients with Familial Colorectal Cancer Type X (FCCTX)
Colorectal cancer (CRC) is the second most common cancer. About 10% of CRC are hereditary including familial adenomatous polyposis (FAP), hereditary non-polyposis colorectal cancer (HNPCC), and rare syndromes. While genetics of FAP and rare syndromes is well studied (APC, STK11, AXIN2), only ∼40-50% of HNPCC have identifiable DNA mismatch-repair gene defects. CRC cases fulfilling Amsterdam Criteria I for HNPCC with normal DNA mismatch repair and elevated risk of microsatellite-stable CRC are called Familial Colorectal Cancer Type X (FCCTX). Compared to HNPCC, FCCTX patients are older, with left-sided CRC, and frequent po...
Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: Melas, M., Luu, H. N., Rennert, G., Lejbkowicz, F., Gruber, S. B., Wiesner, G. L., Raskin, L. Tags: Epidemiology Source Type: research
Ideal colonoscopic surveillance intervals to reduce incidence of advanced adenoma and colorectal cancer
ConclusionsMost family history categories did not confer excess risk above personal history of advanced neoplasia. A prior cancer poses less of a risk than a prior advanced adenoma. Based on our models, a person with an advanced adenoma should be scheduled for colonoscopy at 3 years, corresponding to a 15% risk of advanced neoplasia for a male <56. Guidelines should be updated that uses a 15% risk as a benchmark for calculating surveillance intervals.
Source: Journal of Gastroenterology and Hepatology - January 22, 2015 Category: Gastroenterology Authors: Norm M Good, Finlay A Macrae, Graeme P Young, John O'Dywer, Masha Slattery, William Venables, Trevor J Lockett, Marilla O'Dwyer Tags: Experimental Gastroenterology Source Type: research
Abstract A27: BLM overexpression promotes tumorigenicity in an azoxymethane/dextran sulfate (AOM/DSS) murine model of intestinal cancer
The role of genomic instability in colorectal cancer susceptibility is well established by studies of hereditary non-polyposis colon cancer (HNPCC), its associated disruption of DNA mismatch repair, and other DNA repair deficiencies that predispose to colon cancer. DNA repair deficiency that results in loss of capacity to maintain the genome leads to increased mutation or chromosome instability that in turn increases tumor formation. In some recent experiments using mouse models of cancer, deletion of genomic housekeeping genes promoted tumorigenesis. The Blm gene encodes a RecQ helicase that represses aberrant homologous ...
Source: Molecular Cancer Research - November 13, 2014 Category: Cancer & Oncology Authors: Ebede, K., McIlhatton, M., Hankey, W., Groden, J. Tags: Target Discovery and Validation: Poster Presentations - Proffered Abstracts Source Type: research
Circulating gastrin concentrations in patients at increased risk of developing colorectal carcinoma
ConclusionConcentrations of gastrin precursors are increased in particular groups with an increased risk of developing CRC.
Source: Journal of Gastroenterology and Hepatology - October 21, 2013 Category: Gastroenterology Authors: Adrienne C. Paterson, Finlay A. Macrae, Cathy Pizzey, Graham S. Baldwin, Arthur Shulkes Tags: Clinical Gastroenterology Source Type: research
