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Lynch syndrome or hereditary non polyposis colorectal cancer (HNPCC) in a moroccan family: Case report
Publication date: Available online 17 January 2021Source: Annals of Medicine and SurgeryAuthor(s): F.Z. Outtaleb, A. Alami, N. Serbati, N. Benchakroun, Z. Bouchbika, H. Jouhadi, N. Tawfiq, S. Sahraoui, A. Benider, H. Dehbi
Source: Annals of Medicine and Surgery - January 18, 2021 Category: General Medicine Source Type: research

Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration
Conclusions: These results confirm the high occurrence of CRCs to young patients and the high frequency of rectal localizations in Moroccan population. They mostly show an absence of BRAF mutation, supposing a rarity of MLH1 promoter hypermethylation pathway, which may even partially explain the CRC peculiarities in our context.Virtual SlidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/5868184711716884
Source: Diagnostic Pathology - June 24, 2015 Category: Pathology Authors: Mohammed SekalHassania AmeurtesseLaila ChbaniKarim OuldimSanae BennisMohammed AbkariAmal BoulouzDafr BenajahBasher BenjellounAbdelmalek OusaddenKhalid Ait TalebSaid Ait LaalimImane ToghraiKhalid MazazSamia ArifiNawfel MellasKarima El RhaziTaoufiq Harmouch Source Type: research