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Intraductal papillary mucinous neoplasm of the ileal heterotopic pancreas in a patient with hereditary non-polyposis colorectal cancer: A case report.
We report a case of intraductal papillary mucinous neoplasm (IPMN) originating from the ileal heterotopic pancreas in a patient with hereditary non-polyposis colorectal cancer (HNPCC). A 49-year-old woman had a past history of total colectomy and total hysterectomy with bilateral salpingo-oophorectomy due to colonic adenocarcinoma and endometrial adenocarcinoma 11 years ago. Her parents died from colonic adenocarcinoma and her sister died from colonic adenocarcinoma and endometrial adenocarcinoma. The clinician found an ileal mass with necrotic change and the mass increased in size from 1.7 cm to 2.2 cm during the past 2 y...
Source: World Journal of Gastroenterology : WJG - July 7, 2015 Category: Gastroenterology Authors: Lee SH, Kim WY, Hwang DY, Han HS Tags: World J Gastroenterol Source Type: research

Management of ovarian and endometrial cancers in women belonging to HNPCC carrier families: review of the literature and results of cancer risk assessment in Polish HNPCC families
Conclusions Due to the increased risk of OC and absence of any benefit from gynecological screening reported in the literature it is recommended that prophylactic oophorectomy for female carriers of MMR mutations after 35 year of age should be considered as a risk reducing option. Annual transvaginal ultrasound supported by CA125 or HE4 marker testing should be performed after prophylactic surgery in these women. Due to the high risk of EC it is reasonable to offer, after the age of 35 years, annual clinical gynecologic examinations with transvaginal ultrasound supported by routine aspiration sampli...
Source: Hereditary Cancer in Clinical Practice - January 16, 2015 Category: Cancer & Oncology Source Type: research

Prevalence of occult gynecologic malignancy at the time of risk reducing and nonprophylactic surgery in patients with Lynch syndrome.
CONCLUSIONS: Patients should be counseled about the risks of finding gynecologic cancer at the time of prophylactic or non-prophylactic surgery for Lynch syndrome and HNPCC, and the potential need for additional surgery. PMID: 24211399 [PubMed - as supplied by publisher]
Source: Gynecologic Oncology - November 5, 2013 Category: Cancer & Oncology Authors: Lachiewicz MP, Kravochuck SE, O'Malley MM, Heald B, Church JM, Kalady MF, Drake RD Tags: Gynecol Oncol Source Type: research

Lynch Syndrome Risk Reducing Surgery – Lisa ’ s Story
Hi, I’m very new to all this so don’t really know where to start! I have a condition called Lynch Syndrome or HNPCC. My wonderful mother died 10 years ago at the age of 52 from Endometrial cancer. She previously had Bowel cancer too and at the time a link was not made but we now know she must have has Lynch syndrome too. Lynch syndrome sufferers have an 80% chance of developing Bowel cancer, a 60% chance of developing Endometrial Cancer and 10% chance of developing Ovarian cancer, plus other cancers too. Which is what has lead me to this site. In a few weeks I will be having a Total Hysterectomy and Bilateral ...
Source: The Hysterectomy Association - October 16, 2012 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health endometrial cancer hysterectomy stories lynch syndrome ovarian cancer Source Type: news