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Perirenal perivascular epithelioid cell tumor (PEComa)
Acta Chir Belg. 2021 Feb 26:1-4. Online ahead of print.ABSTRACTA 52-year-old woman who is carrier of MLH-1 mutation (HNPCC-type Lynch syndrome) with a history of a colon adenocarcinoma was diagnosed with a 26 mm lobulated contrast-capturing mass located caudally of the pancreas tail, anteromedial of the spleen and medial of the splenic colon angle. She underwent an exploratory laparotomy with resection of the tumor. Initially this mass was presumed to be a metastasis in a patient with a history of a colon adenocarcinoma. However, after further histopathological and immunohistochemical examination, the mass appeared to be a...
Source: Acta Chirurgica Belgica - February 26, 2021 Category: Surgery Authors: Virginie Camps Vicky Maertens Maarten Michiels Herbert Plasschaert Robrecht Ceulemans Source Type: research

Differential indications for ileoanal pouch anastomosis : Ulcerative colitis, familial adenomatous polyposis, synchronous colorectal cancer - Crohn's disease, constipation.
Abstract Ileoanal pouch anastomosis is the procedure of choice for patients with drug refractory ulcerative colitis, indeterminate colitis and familial adenomatous polyposis (FAP). In selected patient groups this procedure is a treatment option for patients with Crohn's disease, hereditary nonpolyposis colorectal cancer (HNPCC), synchronous colorectal cancer and for severe colorectal constipation refractory to conservative drug treatment. The pouch procedure provides the opportunity to avoid a permanent ileostomy. The majority of surgeons prefer the ileal J‑pouch as the construction is the easiest to perform an...
Source: Der Chirurg - April 12, 2017 Category: Surgery Authors: Fürst A Tags: Chirurg Source Type: research

Hereditary non ‐polyposis colorectal cancer/Lynch syndrome in three dimensions
ConclusionHereditary colorectal cancer can be confusing. Sorting families in three dimensions can clarify the confusion and may direct further testing and, ultimately, surveillance.
Source: ANZ Journal of Surgery - March 16, 2016 Category: Surgery Authors: Sara E. Kravochuck, James M. Church Tags: COLORECTAL SURGERY Source Type: research

Hereditary non‐polyposis colorectal cancer/Lynch syndrome in three dimensions
ConclusionHereditary colorectal cancer can be confusing. Sorting families in three dimensions can clarify the confusion and may direct further testing and, ultimately, surveillance.
Source: ANZ Journal of Surgery - March 16, 2016 Category: Surgery Authors: Sara E. Kravochuck, James M. Church Tags: Original Article Source Type: research

Risk-reduction surgery in pediatric surgical oncology: A perspective
A small percentage of pediatric solid cancers arise as a result of clearly identified inherited predisposition syndromes and nongenetic lesions. Evidence supports preemptive surgery for children with genetic [multiple endocrine neoplasia type 2 (MEN2), familial adenomatous polyposis syndrome (FAP), hereditary nonpolyposis colorectal cancer (HNPCC), and hereditary diffuse gastric cancer (HDGC) and nongenetic [thyroglossal duct cysts (TGDC), congenital pulmonary airway malformations (CPAM), alimentary tract duplication cysts (ATDC), and congenital choledochal cysts (CCC)] developmental anomalies.
Source: Journal of Pediatric Surgery - February 18, 2016 Category: Surgery Authors: John A. Sandoval, Israel Fernandez-Pineda, Alpin D. Malkan Tags: Review Article Source Type: research

Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old
Background: In clinical practice, unexpected diagnosis of colorectal cancer in young patients requires prompt surgery, thus genetic testing for Lynch Syndrome is frequently missed, and clinical management may result incorrect. Methods: Patients younger than 50 years old undergoing colorectal resection for cancer in the period 1994-2007 were identified (Group A, 49 cases), and compared to a group of randomly selected patients more than 50 (Group B, 85 cases). In 31 group A patients, immunohistochemical expression analysis of MLH1, MSH2 and MSH6 was performed; personal and familial history of patients with defective MMR prot...
Source: BMC Surgery - February 17, 2014 Category: Surgery Authors: Gian BaiocchiNazario PortolaniWilliam VermiCarla BaronchelliFederico GhezaClaudio ZognoAlessandro ScagliaEleonora MarchinaGuido TiberioStefano Giulini Source Type: research