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Upper tract urothelial carcinoma: epidemiology, high risk populations, and detection.
Authors: Redrow GP, Matin SF Abstract Upper tract urothelial carcinoma (UTUC) is a rare but highly morbid genitourinary malignancy. In 2014 approximately 15000 new cases were diagnosed in the United States. It accounts for approximately 5-10% of all urothelial cell carcinomas, and 10% of renal tumors. Recent research has increased understanding of the epidemiology of this disease, including several high-risk populations. Environmental exposure to tobacco as well as aristolochic acid, and other carcinogens significantly increase the development of UTUC. Additionally, the genetic condition of hereditary nonpolyposis ...
Source: Minerva Urologica e Nefrologica - March 25, 2016 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research

Molecular aspects of upper tract urothelial carcinoma
Conclusion: Advances in our understanding of the biology of UTUC is may in the future help to identify novel druggable targets, clinically applicable biomarkers and guide treatment of the rare but lethal condition.
Source: Urologic Oncology: Seminars and Original Investigations - February 21, 2013 Category: Urology & Nephrology Authors: Nilay Patel, Manit Arya, Asif Muneer, Tom Powles, Mark Sullivan, John Hines, John Kelly Tags: Abstracts for Online Original Articles and Reviews Source Type: research