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Condition: Chronic Pain

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Total 72 results found since Jan 2013.

CBD Could Help Cops Get Relief From Stress, Insomnia, and Chronic Pain. But Using It Puts Their Job in Jeopardy
There were moments in the past few years when Police Sgt. Brian Vaughan would have tried almost anything to break the cycle of sleeplessness that wore him down—to wash away the images, sounds, and smells of violence that stuck to his memory, and ease the constant pain that was shooting through his back. At one point, he found himself tempted to try CBD, a widely available cannabis derivative that can offer relief from many ailments. “It would have been great to be able to take it and see if it helps,” says Vaughan, a 14-year law enforcement veteran and training coordinator for the police department in Dal...
Source: TIME: Health - July 29, 2022 Category: Consumer Health News Authors: Katja Ridderbusch Tags: Uncategorized Drugs freelance healthscienceclimate Source Type: news

Effect of epidural spinal cord stimulation after chronic spinal cord injury on volitional movement and cardiovascular function: study protocol for the phase II open label controlled E-STAND trial
This study has been approved after full review by the Minneapolis Medical Research Foundation Institutional Review Board and by the Minneapolis VA Health Care System. This project has received Food and Drug Administration investigational device exemption approval. Trial results will be disseminated through peer-reviewed publications, conference presentations and seminars. Trial registration number NCT03026816.
Source: BMJ Open - July 18, 2022 Category: General Medicine Authors: Darrow, D. P., Balser, D. Y., Freeman, D., Pelrine, E., Krassioukov, A., Phillips, A., Netoff, T., Parr, A., Samadani, U. Tags: Open access, Neurology Source Type: research

Spinal cord stimulation for treatment of complex regional pain syndrome: a single-centre retrospective case series study
CONCLUSIONS AND CLINICAL IMPLICATIONS: SCS is the best alternative for patients with CRPS. It should be used immediately after the failure of conservative treatment. Despite the relatively high complication rate in our series, it is the best choice for pain reduction management in this select group of patients.PMID:35722899 | DOI:10.5603/PJNNS.a2022.0038
Source: Neurologia i Neurochirurgia Polska - June 20, 2022 Category: Neurology Authors: Marek Prokopienko Micha ł Sobstyl Source Type: research

The Truth About Common Digestive Health Fears
Everyone experiences digestive problems now and then, and they’re nobody’s idea of a good time. In a survey of nearly 72,000 adults in the U.S., 61% reported having had at least one gastrointestinal (GI) symptom over the previous week, and within that group, 58% said they’d had two or more GI symptoms over the past week, according to a study in a 2018 issue of the American Journal of Gastroenterology. Because symptoms like constipation, heartburn, and abdominal pain are generally vague and often don’t have an obvious cause, those suffering tend to fear the worst. “People get very concerned abo...
Source: TIME: Health - March 14, 2022 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized healthscienceclimate Source Type: news

Can Cannabis Help Your Gut?
When Joe Silverman developed Crohn’s disease at age 21, the symptoms started out mild. While the sight of blood in his stools initially freaked him out, what really bothered him was the frequent abdominal pain and bloating that occurred as his condition progressed to moderate and then severe. Dietary changes didn’t make a difference, so he began taking prescription oral anti-inflammatory drugs that are often used to treat certain bowel diseases, which alleviated but didn’t eliminate his discomfort. He started using prescription steroid suppositories to cope with flare-ups of the inflammatory bowel disease...
Source: TIME: Health - September 23, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Source Type: news

Fecal Transplants: a New Treatment for IBD
Linda Ann Sasser has had ulcerative colitis since she was 20, but it wasn’t until May 2019, about 30 years later, that her condition hit a low point: not only did she have a major flare-up of chronic inflammatory bowel disease (IBD), but on top of it, she had Clostridioides difficile (or C. diff), a highly contagious bacterial infection that causes severe diarrhea and inflammation of the colon. “I became really, really sick with bloody diarrhea 30 times a day and chronic stomach pain,” Sasser says. While hospitalized for 12 days, she was given oral steroid medications, which didn’t help, then IV ste...
Source: TIME: Health - September 9, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Disease feature Source Type: news

Implementation of a pharmacist care manager model to expand availability of medications for opioid use disorder.
CONCLUSION: The need to increase the number of patients receiving MOUD led to the implementation of a CPCM model. The program was effectively implemented into practice and expanded the availability of MOUD, which allowed patients to access treatment in multiple care settings. PMID: 33326564 [PubMed - as supplied by publisher]
Source: American Journal of Health-System Pharmacy : AJHP - December 16, 2020 Category: Drugs & Pharmacology Authors: DeRonne BM, Wong KR, Schultz E, Jones E, Krebs EE Tags: Am J Health Syst Pharm Source Type: research

Network meta-analysis to compare VenaSeal with other superficial venous therapies for chronic venous insufficiency
ConclusionsVenaSeal system is a promising therapeutic option for anatomic success at 6 months, with fewer occurrences of adverse events (wound and groin infection, pulmonary embolism) in CVI patients compared with other interventions in this study. Additional economic analysis including cost-effectiveness analysis would provide interesting perspectives on real-world insights to patients, payers, and providers.
Source: Journal of Vascular Surgery: Venous and Lymphatic Disorders - February 14, 2020 Category: Surgery Source Type: research

Interdisciplinary Pain Neuroscience Continuing Education in the Veterans Affairs: Live Training and Live-Stream With 1-Year Follow-up
Objective: Because of the pain and opioid epidemic in the United States, there is a need to update clinician’s knowledge, attitudes, and beliefs regarding persistent pain across health care disciplines. The aim of this study was to determine if health care professionals can positively change their knowledge, attitudes, and beliefs regarding chronic pain, following a pain neuroscience education (PNE) lecture and 1 year follow-up. Materials and Methods: A total of 270 health care providers at the Minneapolis Veterans Affairs Health Care System received a 3.5-hour PNE lecture in person or via live-stream. Primary outco...
Source: The Clinical Journal of Pain - October 7, 2019 Category: Anesthesiology Tags: Original Articles Source Type: research

Effects of Sweet Cherry Polyphenols on Enhanced Osteoclastogenesis Associated With Childhood Obesity
Conclusions Our study, to our knowledge, is the first demonstrating in obese children a spontaneous osteoclastogenesis inhibited by polyphenols from sweet cherry extracts, through the reduction of TNFα, without affecting cell viability. We also demonstrated that the spontaneous osteoclastogenesis observed in PBMCs from obese children is supported by the high percentage of circulating CD14+/CD16+ cells and the elevated levels of RANKL and TNFα. Our study opens future perspectives for the use of cherry extracts, appropriately formulated as nutraceuticals as preventive in healthy children and therapeu...
Source: Frontiers in Immunology - May 2, 2019 Category: Allergy & Immunology Source Type: research

Finally, a Wearable Neuromodulation Device for Overactive Bladder
As a urogynecology surgeon, Alexandra Haessler, MD, has seen firsthand the limitations of current overactive bladder (OAB) therapies. Aside from medication, the current gold standard for OAB is Medtronic's InterStim, an implantable sacral neuromodulation device that is FDA approved for the treatment of OAB as well as chronic fecal incontinence, and non-obstructive urinary retention. Haessler told MD+DI that the InterStim device works very well but it's an expensive treatment and access is limited because only a few subspecialists in any one metropolitan area are truly qualified to deliver the therapy. The InterStim is not ...
Source: MDDI - April 19, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Conclusion and Future Directions G protein bias may either be affinity/potency-dominant or efficacy-dominant (Table 1). A potential concern is that, despite using the same cellular assays, variations in agonist potency were determined by different, or even the same labs, potentially due to differences in expression levels of the receptor and signaling proteins that occurred during cell passaging. For example the reported arrestin recruitment potency for U69,593 has been reported to be as low as 67.7 nM (Spetea et al., 2017) and as high as 410 nM (Dunn et al., 2018), similarly for U50,488 potency has ranged from 36 to 1000...
Source: Frontiers in Pharmacology - April 16, 2019 Category: Drugs & Pharmacology Source Type: research

Diagnosis and Management of Trochleodynia, Trochleitis, and Trochlear Headache
Conclusion Trochlear pain (trochleodynia) is becoming recognized as a set of disorders that can present in isolation or concomitantly with co-existing migraines, tension-type headaches, or other headache disorders, possibly explaining subpar symptom control in a small but significant number of individuals globally. Trochleodynia features unilateral periocular pain that may involve the ipsilateral hemicranium. Pain exacerbation occurs with trochlear palpation and supraduction of the affected eye especially in the adducted position. Trochleodynia may respond to oral NSAIDs if symptoms are mild and of recent onset. While ora...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

(370) Opioid Management in Primary Care: A Response to the Opioid Epidemic
In March 2016, in response to a national opioid epidemic, the CDC released guidelines for prescribing opioids for chronic pain.   Pain Specialists at a comprehensive, interdisciplinary Pain Clinic within an integrated health system in suburban Minneapolis, Minnesota - a Clinic designed in large part to respond to the opioid epidemic - evaluated patients for participation in a pain treatment program with emphasis on SELF- ve rsus MEDICATION-management of their chronic pain.  While recognizing success in the Pain Clinic (95% of the patients had maintained decreased opioid use, and 38% of the patients showed a 100% reductio...
Source: The Journal of Pain - March 21, 2019 Category: Materials Science Authors: G. Panopoulos, S. Ferron, A. Schroepfer, L. Anderson, M. Dargay, A. Roslin, B. Votel, T. Robbins, C. Holte, D. Mullen, G. Fedio, A. Clavel Source Type: research