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Which Drugs Work Best for ADHD? Large Study Zeroes in on Two
The researchers compared seven ADHD drugs -- amphetamines (including lisdexamfetamine), atomoxetine, bupropion, clonidine, guanfacine, methylphenidate and modafinil -- and a placebo over 12 weeks of treatment.
Source: WebMD Health - August 8, 2018 Category: Consumer Health News Source Type: news

Self-Inflicted Injuries Surge Among Tween & Early Teen Girls
By Susan Scutti, CNN (CNN) — Emergency room visits for non-fatal, self-inflicted injuries surged in recent years among US girls and young women, especially those between the ages of 10 and 14, according to a new study. However, rates of self-harm among boys and young men between the ages of 10 and 24 remained stable throughout the years 2001 through 2015, the researchers said. “Suicide is preventable,” said Melissa C. Mercado, lead author of the study published Tuesday in JAMA and a behavioral scientist at the US Centers for Disease Control and Prevention. “These findings underscore the need for the...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 21, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Suicide Source Type: news

Medication finds new use in sustaining opioid quit success
New research suggests that clonidine, a medication for high blood pressure and attention deficit hyperactivity disorder (ADHD), can enhance buprenorphine’s ability to treat opioid dependence. This combination of medications reduces stress-induced craving and prolongs opioid abstinence during...
Source: NIDA News - March 18, 2015 Category: Addiction Tags: Health and Medical Professionals, Opioids, Treatment Research Source Type: news

Case report: guanfacine overdose
Intuniv (Guanfacine) 3 out of 5 stars Prolonged Bradycardia and Hypotension Following Guanfacine Extended Release Overdose. Walton J et al. J Child Adolesc Physcopharmacol 2014 Jul 10 [Epub ahead of print] Reference  Guanfacine is a central α2-agonist with a mechanism of action similar to that of clonidine. Originally marketed as an antihypertensive agent, it is now available as an extended-release preparation (Imtuniv) for treating children ages 6-17 with attention-deficit hyperactivity disorder (ADHD). It is thought the mechanism of action in that condition may involve stimulation of α2-receptors in the prefrontal c...
Source: The Poison Review - July 18, 2014 Category: Toxicology Authors: Leon Tags: Medical ADHD attention deficit hyperactivity disorder clonidine guanfacine Source Type: news

Clonidine and other central alpha-2 agonists: can one pill kill a toddler?
3 out of 5 stars Unintentional Pediatric Exposures to Central Alpha-2 Agonists Reported to the National Poison Data System. Wang GS et al. J Pediatr 2013 Oc 1 [Epub ahead of print] Abstract Central alpha-2 agonists — clonidine, guanfacine, and tizanidine — are increasingly being used for approved and off-label indications, including hypertension, muscle spasms, tics, and opioid withdrawal. Extended-release forms of guanfacine (Intuniv) and clonidine (Kapvay) have been approved for treatment of attention-deficit hyperactivity disorder (ADHD). These drugs are selective agonists at the central presynaptic alpha-2 adrener...
Source: The Poison Review - November 9, 2013 Category: Toxicology Authors: Leon Tags: Medical central alpha-2 agonist clonidine guanfacine intuniv kapvay kill one pill pediatric tizanidine Source Type: news

Myths & Truths about Tourette Syndrome
This study also found a decrease in tics in adults who received CBIT. Unfortunately, behavior therapy isn’t widely available. Medication is used more frequently to treat tics. Doctors typically prescribe clonidine or guanfacine as the first line of treatment, Woods said. They also may prescribe atypical antipsychotics, such as risperidone, he added. 4. Myth: Teaching kids to suppress one tic will trigger more or different tics. Fact: Research has found that when kids successfully suppress their tics, they don’t experience an increase in tics. One study even found that after the suppression condition, tics decreased by...
Source: Psych Central - August 29, 2013 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Atypical Antipsychotics Children and Teens Disorders General Medications Psychotherapy Self-Help Treatment Attention Deficit Hyperactivity Attention Deficit Hyperactivity Disorder Behavior Therapy CBIT Clinical Psychologist Commo Source Type: news

DSM-5 likely to increase cases of ADHD drug overdose
3.5 out of 5 stars Overdose of Drugs for Attention-Deficit Hyperactivity Disorder: Clinical Presentation, Mechanisms of toxicity, and Management. Spiller HA et al. CNS Drugs 2013 Jun 12 [Epub ahead of print] Abstract There is a very good chance that in the near future we will see an increasing number of cases involving ingestion or overdose of drugs used to treat Attention-Deficit Hyperactivity Disorder (ADHD). DSM-5, released last month, has changed criteria for making a diagnosis of ADHD that will radically expand the the population of both children and adults who could be labelled with the condition and be candidates f...
Source: The Poison Review - July 3, 2013 Category: Toxicology Authors: Leon Tags: Medical adderall ADHD atomoxetine attention deficit hyperactivity disorder clonidcine DSM guanfacine modafinil psychostimulant. methylphenidate Source Type: news

Foodborne Illness Could Have Sinister Causes
Doctors should consider the intentional addition of medicine to food as a potential cause of foodborne disease outbreaks. The World Health Organization suggests possible sources of foodborne disease outbreaks are pathogenic bacteria, viruses, protozoa, parasitic worms, natural toxins, and chemicals, but not medicines. A 2010 foodborne disease outbreak in Beijing, China was a result of clonidine, a medication used to treat hypertension and ADHD, being intentionally added to lunch ingredients. Eighty travelers who had just finished lunch in a Beijing restaurant began to feel faint...
Source: Health News from Medical News Today - January 4, 2013 Category: Consumer Health News Tags: Primary Care / General Practice Source Type: news