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Total 73 results found since Jan 2013.
TWiV 300: So happy together
Recording together for the first time, the hosts of the science show This Week in Virology celebrate their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent speaks with Dickson, Alan, Rich, and Kathy about their careers in science.
You can find TWiV #300 at www.twiv.tv.
Source: virology blog - August 31, 2014 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Alan Dove dickson despommier ebola virus Kathy Spindler podcast research Rich Condit science career TWiV viral Source Type: blogs
An open letter to Psychological Medicine, again!
In conclusion, noted Wilshire et al., “the claim that patients can recover as a result of CBT and GET is not justified by the data, and is highly misleading to clinicians and patients considering these treatments.”
In short, the PACE trial had null results for recovery, according to the protocol definition selected by the authors themselves. Besides the inflated recovery results reported in Psychological Medicine, the study suffered from a host of other problems, including the following:
*In a paradox, the revised recovery thresholds for physical function and fatigue–two of the four recovery measures–were so lax ...
Source: virology blog - March 23, 2017 Category: Virology Authors: Vincent Racaniello Tags: Commentary Information adaptive pacing therapy CFS chronic fatigue syndrome clinical trial cognitive behavior therapy Dave Tuller exercise graded exercise therapy mecfs myalgic encephalomyelitis outcome PACE trial recovery Source Type: blogs
TWiV 214: This is your brain on polyomavirus
On episode #214 of the science show This Week in Virology, Vincent, Alan, and Kathy discuss how coagulation factor X binding to adenovirus activates the innate immune system, and a novel polyomavirus associated with brain tumors in raccoons.
You can find TWiV #214 at www.twiv.tv.
Source: virology blog - January 7, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology adenovirus chemokine coagulation factor cytokine factor X gene therapy innate immunity malignant peripheral nerve sheath tumor polyomavirus sarcoma TLR4 viral Source Type: blogs
WHO will switch to type 2 inactivated poliovirus vaccine
The World Health Organization’s campaign to eradicate poliomyelitis made impressive inroads in 2012: only 212 cases were reported, compared with 620 the previous year; moreover, India remained polio-free. The dark side of this story is that as wild polio is eliminated, vaccine-associated poliomyelitis moves in to take its place. The landmark decision by WHO to replace the infectious, type 2 Sabin poliovaccine with inactivated vaccine is an important step towards eliminating vaccine-associated polio.
A known side effect of the Sabin poliovirus vaccines, which are taken orally and replicate in the intestine, is vaccine...
Source: virology blog - January 8, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information eradication IPV OPV polio poliomyelitis poliovirus Sabin Salk vaccine VDPV viral WHO world health organization Source Type: blogs
Poliovirus on Time
Poliovirus has made the cover of Time magazine.
The Time cover image for the 14 January 2013 issue is a model of poliovirus bound to a soluble form of its cellular receptor, CD155. I was part of the team that solved the structure of this complex in 2000, together with the laboratories of Jim Hogle and Alasdair Steven. The structure of the same complex was also solved by Rossmann’s group. The image that Time used for the cover was produced by Laguna Design, although I do not know whether they used our structural information or Rossmann’s.
The Time cover image is accompanied by the text: One thing stands in the w...
Source: virology blog - January 12, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information cd155 jeffrey kluger poliovirus pvr receptor time magazine viral Source Type: blogs
TWiV 215: Illuminating rabies and unwrapping a SARI
On episode #215 of the science show This Week in Virology, Vincent, Alan, and Kathy review the finding that rabies virus infection alters but does not kill neurons, and provide an update on the novel coronavirus in the Middle East.
You can find TWiV #215 at www.twiv.tv.
Source: virology blog - January 13, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology coronavirus EMC genome Middle East neuron rabid rabies receptor SARI SARS tropism viral Source Type: blogs
TWiV 216: Processing VIRALGUUAACACCAGRNA
On episode #216 of the science show This Week in Virology, Vincent, Alan, Rich, and Kathy resume the virology 101 series with a discussion of RNA capping, splicing, and export.
You can find TWiV #216 at www.twiv.tv.
Source: virology blog - January 20, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology GpppG hnRNA lariat methylation mRNA cap nuclear export polyA rna splicing transesterification undecanucleotide viral virus Source Type: blogs
TWiV 217: I just flu in and my arms are shot
On episode #217 of the science show This Week in Virology, Vincent, Alan, Rich, and Dickson review influenza vaccines.
You can find TWiV #217 at www.twiv.tv.
Source: virology blog - January 27, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology adjuvant afluria cell culture efficacy egg fluarix flulaval flumist fluvirin H5N1 influenza LAIV narcolepsy pandemic pandemrix TIV vaccine viral virus Source Type: blogs
TWiV 218: Monkeys turning valves and pushing buttons
On episode #218 of the science show This Week in Virology, Vincent, Alan, and Welkin discuss how endogenous retroviruses in mice are held in check by the immune response.
You can find TWiV #218 at www.twiv.tv.
Source: virology blog - February 3, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antibody cancer endogenous retrovirus ERV germline murine leukemia virus RAG mouse reactivation TLR toll-like receptor tumor viral Source Type: blogs
TWiV 220: Flu watches the clock while T7 gets a CAT scan
On episode #220 of the science show This Week in Virology, Vincent, Rich, Alan, and Kathy discuss regulation of influenza virus replication by splicing, and the bacteriophage T7 random walk.
You can find TWiV #220 at www.twiv.tv.
Source: virology blog - February 17, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology bacteriophage t7 cryo-electron tomography Cryo-ET influenza NEP NS1 NS2 nuclear export protein rna splicing viral virus Source Type: blogs
Comment on H5N1 lethality in humans
In a brief letter to Biosecurity and Bioterrorism, Alan Zelicoff notes a problem with serosurveys for influenza H5N1 infection:
…peak titers after H5N1 infection occur at about 4 to 6 weeks postinfection and may drop by as much as 32-fold over the course of a year, probably decreasing the sensitivity of serologic testing for past asymptomatic infections. Micro-neutralization testing may be more sensitive.
He cites a serological survey carried out on poultry workers in South Korea, in which 9 of 2,500 subjects were found to have antibodies to H5N1 virus, in the absence of illness. These seropositive individuals carrie...
Source: virology blog - February 18, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information avian influenza H5N1 bioterrorism microneutralization serological survey serosurvey viral virus Source Type: blogs
This week in virology, parasitism, and microbiology
In the past five days we released three science shows on the TWi* network.
On This Week in Microbiology (TWiM) episode #52, Vincent and Michael meet up with Ellen Jo Baron to talk about working in a clinical microbiology laboratory.
On This Week in Parasitism (TWiP) episode #52, Vincent and Dickson review the life cycle and pathogenesis of the giant kidney worm, Dioctophyme renale.
On This Week in Virology (TWiV) episode #224, Vincent, Alan, Kathy, and Dickson discuss identification of a cell receptor for the coronavirus-EMC, and the role of interferon-epsilon in protecting the female reproductive tract.
Thanks for listening.
Source: virology blog - March 17, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Microbiology This Week in Parasitism This Week in Virology clinical microbiology coronavirus EMC dioctophyme renale ellen jo baron giant kidney worm interferon epsilon viral Source Type: blogs
TWiV 223: EEEV and the serpent
On episode #223 of the science show This Week in Virology, Vincent, Alan, and Kathy discuss new influenza virus NA inhibitors, detection of EEEV antibody and RNA in snakes, and replication of the coronavirus EMC in human airway epithelial cells.
You can find TWiV #223 at www.twiv.tv.
Source: virology blog - March 10, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology alphavirus coronavirus EMC eastern equine encephalitis virus EEEV human airway epithelial cells influenza neuraminidase relenza snakes tamiflu togavirus viral zoonotic Source Type: blogs
TWiV 229: Partly cloudy with a high of H7N9
On episode #229 of the science show This Week in Virology, Vincent, Rich, Dickson, and Alan review the current status of human infections with avian influenza H7N9 virus.
You can find TWiV #229 at www.twiv.tv.
Source: virology blog - April 21, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology avian H7N9 brambling China duck H2N9 influenza pandemic reassortant Shanghai vaccine viral virus WHO wild bird Source Type: blogs
TWiV 230: Gene goes to Washington, flu chickens out
On episode #230 of the science show This Week in Virology, Vincent, Rich, Alan and Kathy review H7N9 infections in China, the debate over patenting genes, and receptor-binding by ferret-transmissible avian H5 influenza virus.
You can find TWiV #230 at www.twiv.tv.
Source: virology blog - April 28, 2013 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology aerosol avian influenza H7N9 China ferret gene patent H5N1 poultry receptor binding Shanghai sialic acid Supreme Court of the United States transmission viral virus Source Type: blogs
