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Cancer: Skin Cancer
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Total 434 results found since Jan 2013.
Mutational landscape and predictors of survival in head and neck mucosal melanoma
Key PointsHead and neck mucosal melanomas have a diverse mutational landscape with low mutational burden.A molecular subset ( ∼13%) has ROS1 mutations, which is an actionable driver mutation.ROS1-mutated patients have improved overall survival likely due to high mutational burden.
Source: International Forum of Allergy and Rhinology - September 8, 2023 Category: Allergy & Immunology Authors: Brandon M. Lehrich,
Arash Abiri,
Theodore V. Nguyen,
Benjamin F. Bitner,
Charles C. L. Tong,
Edward C. Kuan Tags: RESEARCH NOTE Source Type: research
Pinpointing Key Features of Gut Dysbiosis in Melanoma Pinpointing Key Features of Gut Dysbiosis in Melanoma
Fecal microbiota profiles differ among patients with melanoma and those without as well as between patients with early stage and late-stage disease, new data suggest.Medscape Medical News
Source: Medscape Allergy Headlines - September 1, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news
Predictive factors for decreased baseline quality of life in patients with sinonasal malignancies
ConclusionsOur findings demonstrate a negative impact on baseline QOL in patients with SNMs and suggest sex-specific and symptom-related lower QOL scores, with minimal histopathology association. Anatomical tumor involvement may be more reflective of QOL than T-staging, as orbital and skull base erosion, PNI, and palate lesions are significantly associated with reduced baseline QOL.
Source: International Forum of Allergy and Rhinology - August 30, 2023 Category: Allergy & Immunology Authors: Cara M. Fleseriu,
Daniel M. Beswick,
Sabrina L. Maoz,
Peter H. Hwang,
Garret Choby,
Edward C. Kuan,
Erik P. Chan,
Nithin D. Adappa,
Mathew Geltzeiler,
Anne E. Getz,
Ian M. Humphries,
Christopher H. Le,
Waleed M. Abuzeid,
Eugene H. Chang,
Ari Tags: ORIGINAL ARTICLE Source Type: research
Anti-tumor activity of trimethoprim-sulfamethoxazole against melanoma skin cancer through triggering allergic reaction and promoting immunity
This study examined the potential roles of TMP-SMX in melanoma skin cancer using an immunodeficient mouse model. TMP-SMX significantly improved the survival rate and reduced the tumor weight and growth and vascular endothelial growth factor levels in melanoma skin cancer of immunodeficient mice. In the forced swimming test, TMP-SMX significantly reduced immobility time compared to the melanoma skin cancer of immunodeficient mice, indicating improved immunity. TMP-SMX significantly increased infiltration of mast cells and release of allergy-related mediators (IgE, histamine, interleukin (IL)-4, IL-5, IL-13, and IL-33) and i...
Source: International Immunopharmacology - August 3, 2023 Category: Allergy & Immunology Authors: Hee-Yun Kim Ho-Geun Kang Hyung-Min Kim Hyun-Ja Jeong Source Type: research
Are AI-Powered Skin-Check Tools on the Horizon? Are AI-Powered Skin-Check Tools on the Horizon?
Primary care might be the first setting where AI-driven tools allow for broader access to effective melanoma screening, amid continuing challenges in developing consumer apps for this purpose.Medscape Medical News
Source: Medscape Allergy Headlines - August 1, 2023 Category: Allergy & Immunology Tags: Dermatology News Source Type: news
Microneedle-assisted transdermal delivery of perfluorotripropylamine-based oxygenated emulsion gel loaded with 5-aminolevulinic acid for enhanced photodynamic therapy of cutaneous squamous cell carcinoma
In conclusion, the 5-ALA-PBOEG plus microneedle treatment shows great potential in the fight against CSCC and other skin cancers.PMID:37302770 | DOI:10.1016/j.ejps.2023.106493
Source: Cancer Control - June 11, 2023 Category: Cancer & Oncology Authors: Jialiang Zhang Qiang Feng Jianbin Xiao Jinyu Zhang Jiao Lin Jianmin Wang Source Type: research
Recurrence patterns among patients with sinonasal mucosal melanoma: a multi ‐institutional study
ConclusionSNMM is associated with a high recurrence rate and poor survival. Primary treatment of the neck was not associated with reduced recurrence, and immunotherapy for treatment of distant recurrence was associated with increased 12-month PRS.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - June 2, 2023 Category: Allergy & Immunology Authors: Vivek C. Pandrangi,
Jess C. Mace,
Arash Abiri,
Nithin D. Adappa,
Daniel M. Beswick,
Eugene H. Chang,
Jacob G. Eide,
Nicholas Fung,
Michelle Hong,
Brian J. Johnson,
Michael A. Kohanski,
Rijul S. Kshirsagar,
Edward C. Kuan,
Christopher H. Le,
Tags: ORIGINAL ARTICLE Source Type: research
The Role of Positron Emission Tomography for the Management of Sinonasal Malignancies: A Systematic Review
CONCLUSIONS: In general, and across all types of sinonasal malignancies, PET scan yielded positive results regarding detection and initial staging. It was also considered as the modality of choice for detection of distant metastases, except in the case of sinonasal lymphoma. PET scan's main limit resides in its inability to detect lesions in or close to the metabolic activity of the brain.PMID:37229633 | DOI:10.1177/19458924231177854
Source: American Journal of Rhinology and Allergy - May 25, 2023 Category: ENT & OMF Authors: David El-Adem Nathan Yang David A Gudis Source Type: research
