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Cancer: Melanoma
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Total 290 results found since Jan 2013.
Mutational landscape and predictors of survival in head and neck mucosal melanoma
Key PointsHead and neck mucosal melanomas have a diverse mutational landscape with low mutational burden.A molecular subset ( ∼13%) has ROS1 mutations, which is an actionable driver mutation.ROS1-mutated patients have improved overall survival likely due to high mutational burden.
Source: International Forum of Allergy and Rhinology - September 8, 2023 Category: Allergy & Immunology Authors: Brandon M. Lehrich,
Arash Abiri,
Theodore V. Nguyen,
Benjamin F. Bitner,
Charles C. L. Tong,
Edward C. Kuan Tags: RESEARCH NOTE Source Type: research
Pinpointing Key Features of Gut Dysbiosis in Melanoma Pinpointing Key Features of Gut Dysbiosis in Melanoma
Fecal microbiota profiles differ among patients with melanoma and those without as well as between patients with early stage and late-stage disease, new data suggest.Medscape Medical News
Source: Medscape Allergy Headlines - September 1, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news
Anti-tumor activity of trimethoprim-sulfamethoxazole against melanoma skin cancer through triggering allergic reaction and promoting immunity
This study examined the potential roles of TMP-SMX in melanoma skin cancer using an immunodeficient mouse model. TMP-SMX significantly improved the survival rate and reduced the tumor weight and growth and vascular endothelial growth factor levels in melanoma skin cancer of immunodeficient mice. In the forced swimming test, TMP-SMX significantly reduced immobility time compared to the melanoma skin cancer of immunodeficient mice, indicating improved immunity. TMP-SMX significantly increased infiltration of mast cells and release of allergy-related mediators (IgE, histamine, interleukin (IL)-4, IL-5, IL-13, and IL-33) and i...
Source: International Immunopharmacology - August 3, 2023 Category: Allergy & Immunology Authors: Hee-Yun Kim Ho-Geun Kang Hyung-Min Kim Hyun-Ja Jeong Source Type: research
Are AI-Powered Skin-Check Tools on the Horizon? Are AI-Powered Skin-Check Tools on the Horizon?
Primary care might be the first setting where AI-driven tools allow for broader access to effective melanoma screening, amid continuing challenges in developing consumer apps for this purpose.Medscape Medical News
Source: Medscape Allergy Headlines - August 1, 2023 Category: Allergy & Immunology Tags: Dermatology News Source Type: news
Recurrence patterns among patients with sinonasal mucosal melanoma: a multi ‐institutional study
ConclusionSNMM is associated with a high recurrence rate and poor survival. Primary treatment of the neck was not associated with reduced recurrence, and immunotherapy for treatment of distant recurrence was associated with increased 12-month PRS.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - June 2, 2023 Category: Allergy & Immunology Authors: Vivek C. Pandrangi,
Jess C. Mace,
Arash Abiri,
Nithin D. Adappa,
Daniel M. Beswick,
Eugene H. Chang,
Jacob G. Eide,
Nicholas Fung,
Michelle Hong,
Brian J. Johnson,
Michael A. Kohanski,
Rijul S. Kshirsagar,
Edward C. Kuan,
Christopher H. Le,
Tags: ORIGINAL ARTICLE Source Type: research
The Role of Positron Emission Tomography for the Management of Sinonasal Malignancies: A Systematic Review
CONCLUSIONS: In general, and across all types of sinonasal malignancies, PET scan yielded positive results regarding detection and initial staging. It was also considered as the modality of choice for detection of distant metastases, except in the case of sinonasal lymphoma. PET scan's main limit resides in its inability to detect lesions in or close to the metabolic activity of the brain.PMID:37229633 | DOI:10.1177/19458924231177854
Source: American Journal of Rhinology and Allergy - May 25, 2023 Category: ENT & OMF Authors: David El-Adem Nathan Yang David A Gudis Source Type: research
Asthma Tied to Increased Risk for Multiple Cancers Asthma Tied to Increased Risk for Multiple Cancers
Asthma appears to increase the risk for melanoma as well as lung, blood, kidney, and ovarian cancers, but treatment with an inhaled steroid might reduce that risk.Medscape Medical News
Source: Medscape Allergy Headlines - May 6, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news
Tiny implantable device designed by UCLA scientists helps kill cancer
Many solid tumors resist treatment in part by turning human biology against itself. Tumors surround themselves with extra white blood cells known as regulatory T cells, which call off the body ’s natural defenses against the disease.Strategies to treat cancer by deactivating these cells risk creating other serious problems. Since regulatory T cells play an important role in safeguarding healthy tissues, diminishing them throughout the body can lead to other immune cells mistakenly attacking these tissues and causing autoimmune conditions that damage the colon, liver, heart and other organs.Now, an interdisciplinary UCLA ...
Source: UCLA Newsroom: Health Sciences - January 4, 2023 Category: Universities & Medical Training Source Type: news
Melanoma Mortality Rates Fell in 2010s as New Therapies Took Hold Melanoma Mortality Rates Fell in 2010s as New Therapies Took Hold
"This data is very encouraging and represents the real-world effectiveness of these newer therapies, which include immunotherapies and targeted therapies."MDedge News
Source: Medscape Allergy Headlines - December 13, 2022 Category: Allergy & Immunology Tags: Dermatology News Source Type: news
