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Total 241 results found since Jan 2013.

Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance
CONCLUSION: We demonstrate impaired immunity following SARS-CoV-2 mRNA immunization in a murine model of comorbid T2DM and obesity, supporting the need for further research into the basis for impaired anti-SARS-CoV-2 immunity in T2DM and investigation of novel approaches to enhance vaccine immunogenicity among those with metabolic diseases.PMID:37595760 | DOI:10.1016/j.jaci.2023.06.031
Source: Clinical Lung Cancer - August 18, 2023 Category: Cancer & Oncology Authors: Timothy R O'Meara Etsuro Nanishi Marisa E McGrath Soumik Barman Danica Dong Carly Dillen Manisha Menon Hyuk-Soo Seo Sirano Dhe-Paganon Robert K Ernst Ofer Levy Matthew B Frieman David J Dowling Source Type: research

Anaphylaxis and systemic mastocytosis controlled with KIT inhibitors in a patient with metastatic lung adenocarcinoma
A 58 ‐year‐old female with indolent systemic mastocytosis (ISM) and metastatic non‐ small cell lung cancer (NSCLC) presented with anaphylaxis to osimertinib with three attempts at rapid drug desensitization (RDD).
Source: Annals of Allergy, Asthma and Immunology - August 16, 2023 Category: Allergy & Immunology Authors: Camellia L. Hernandez, Donna ‐Marie Lynch, Abby Jane Golash, Kathleen Marquis, Kylie Marie Besz, Geoffrey Oxnard, Julia Rotow, Daniel J. DeAngelo, Mariana Castells Tags: Letters Source Type: research

Emollients for preventing atopic eczema: Cost-effectiveness analysis of the BEEP trial
CONCLUSIONS: In line with effectiveness endpoints, advice given in the BEEP trial to apply daily emollient during infancy for eczema prevention in high-risk children does not appear cost-effective.PMID:37574761 | DOI:10.1111/cea.14381
Source: Clinical Lung Cancer - August 14, 2023 Category: Cancer & Oncology Authors: Tracey H Sach Stella T Lartey Charlotte Davies Joanne R Chalmers Rachel H Haines Lucy E Bradshaw Alan A Montgomery Kim S Thomas Sara J Brown Matthew J Ridd Sandra Lawton Mike J Cork Carsten Flohr Eleanor Mitchell Richard Swinden Laura Wyatt Stella Tarr Su Source Type: research

What AI Can See in CT Scans That Humans Can ' t What AI Can See in CT Scans That Humans Can ' t
More can be learned from a chest CT than whether early lung cancer is present.Medscape
Source: Medscape Allergy Headlines - July 25, 2023 Category: Allergy & Immunology Tags: Internal Medicine Commentary Source Type: news

COPD and biologic treatment: state of the art
Curr Opin Allergy Clin Immunol. 2023 Jun 21. doi: 10.1097/ACI.0000000000000920. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Chronic Obstructive Pulmonary Disease (COPD) is a common, heterogeneous disease associated with abnormal inflammatory response of the lung to noxious particles and gases. The progression of disease leads to respiratory failure, disability and premature death. Although recent progress in reducing the global burden of many chronic disease, such as heart disease and cancer, mortality and morbidity due to COPD continue to increase despite of cigarette smoking worldwide policy. Additionally, diagnosti...
Source: Clinical Lung Cancer - June 26, 2023 Category: Cancer & Oncology Authors: Sebastian Ferri Giovanni Paoletti Corrado Pelaia Enrico Heffler Giorgio Walter Canonica Francesca Puggioni Source Type: research

Perspectives on Mycophenolate Mofetil in the Management of Autoimmunity
Clin Rev Allergy Immunol. 2023 Jun 20. doi: 10.1007/s12016-023-08963-3. Online ahead of print.ABSTRACTBefore becoming a cornerstone in the treatment of numerous immune-mediated diseases, mycophenolate mofetil (MMF) was first introduced as an immunosuppressive agent in transplant immunology and later received the attention of rheumatologists and clinicians involved in the management of autoimmune diseases. MMF is now a widespread immunosuppressive drug for the treatment of several conditions, including lupus nephritis, interstitial lung disease associated with systemic sclerosis, and anti-neutrophil cytoplasm antibody (ANCA...
Source: Clinical Lung Cancer - June 20, 2023 Category: Cancer & Oncology Authors: Rithika Bhat Antonio Tonutti Suraj Timilsina Carlo Selmi M Eric Gershwin Source Type: research

Electronic Nose May Sniff Out Early Lung Cancer in COPD Electronic Nose May Sniff Out Early Lung Cancer in COPD
An electronic exhaled breath analyzer showed differences in breath profiles of patients with COPD who went on to develop lung cancer.Medscape Medical News
Source: Medscape Allergy Headlines - June 15, 2023 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news

Updated Guidance Regarding The Risk ofAllergic Reactions to COVID-19 Vaccines and Recommended Evaluation and Management: A GRADE Assessment, and International Consensus Approach
J Allergy Clin Immunol. 2023 Jun 7:S0091-6749(23)00746-7. doi: 10.1016/j.jaci.2023.05.019. Online ahead of print.ABSTRACTThis guidance updates 2021 GRADE recomendations regarding immediate allergic reactions following COVID-19 vaccines and addresses re-vaccinating individuals with 1st dose allergic reactions and allergy testing to determine re-vaccination outcomes. Recent meta-analyses assessed the incidence of severe allergic reactions to initial COVID-19 vaccination, risk of mRNA-COVID-19 re-vaccination after an initial reaction, and diagnostic accuracy of COVID-19 vaccine and vaccine excipient testing in predicting reac...
Source: Clinical Lung Cancer - June 9, 2023 Category: Cancer & Oncology Authors: Matthew Greenhawt Timothy E Dribin Elissa M Abrams Marcus Shaker Derek K Chu David Bk Golden Cem Akin Akterini Anagnostou Faisal ALMuhizi Waleed Alqurashi Peter Arkwright James L Baldwin Aleena Banerji Philippe B égin Moshe Ben-Shoshan Jonathan Bernstein Source Type: research

Lung Cancer Device Study Raises Concerns for Commercial Use Lung Cancer Device Study Raises Concerns for Commercial Use
Novocure Ltd ' s experimental device to treat a type of lung cancer helped in extending overall survival among patients in a late-stage study, but concerns around its commercial success sent shares down 34%.Reuters Health Information
Source: Medscape Allergy Headlines - June 7, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news

Safe to Stop Immunotherapy at 2 Years in Stable Lung Cancer Safe to Stop Immunotherapy at 2 Years in Stable Lung Cancer
A large review has found no difference in overall survival with fixed-duration vs ongoing ICI treatment in progression-free non –small cell lung cancer.Medscape Medical News
Source: Medscape Allergy Headlines - June 6, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news

Genetic ancestry is associated with asthma, and this could be modified by environmental factors. A systematic review
Clin Exp Allergy. 2023 Apr 13. doi: 10.1111/cea.14308. Online ahead of print.NO ABSTRACTPMID:37051940 | DOI:10.1111/cea.14308
Source: Clinical Lung Cancer - April 13, 2023 Category: Cancer & Oncology Authors: Jonathan Pham Dinh S Bui Caroline J Lodge Michael J Abramson Adrian J Lowe Shuai Li Aung K Win Mark Hew Shyamali C Dharmage Source Type: research