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Total 379 results found since Jan 2013.

80 years of skin testing evaluation in annals
When reading the article entitled “Evaluation of skin testing in allergy: a discussion of causative factors in misleading reactions,” one cannot help but acknowledge that Lieutenant Commander Steele's review written 80 years ago is a lesson in humility.1 Well before the discovery of immunoglobulin E or the mast cell, Dr Steele a cknowledges skin testing's utility no differently than we would today. He writes that it is only a valuable adjunct to the clinical findings while rejecting the skeptic's view that it is “a semi-cabalistic rite bordering on charlatanism” or the overzealous advocate's overinterpretation of minor variations.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: John J. Oppenheimer, Harold Nelson Tags: Editorial Source Type: research

Politicians, scientists spar over alleged NIH cover-up using COVID-19 origin paper
Two scientists who are coauthors of a 3-year-old article on the origin of the COVID-19 pandemic faced down Republican lawmakers today in what might be the most in-depth discussion ever of a scientific paper in the halls of the U.S. Congress. At a House subcommittee hearing , the Republicans asserted that top officials at the U.S. National Institutes of Health (NIH) prompted the researchers to write the paper to try and “kill” the theory that SARS-CoV-2 leaked from a laboratory in Wuhan, China. The scientists, two of its five co-authors, flatly rejected the allegation. And as the hearing extended over 3 hours, com...
Source: Science of Aging Knowledge Environment - July 11, 2023 Category: Geriatrics Source Type: research

Lessons from Dairy Farmers for Occupational Allergy and Respiratory Disease
AbstractPurpose of ReviewExposure to bioaerosols at dairies has long been associated with allergy, respiratory disease, and decreases in lung function. Recent advancements in exposure assessments have aided our understanding on the size distribution and composition of these bioaerosols, but investigations focusing solely on exposures may overlook important intrinsic factors impacting worker ’s susceptibility to disease.Recent FindingsIn our review, we discuss the most recent studies examining the exposures and genetic factors that contribute to occupational disease in dairy work. We also review more recent concerns in li...
Source: Current Allergy and Asthma Reports - May 16, 2023 Category: Allergy & Immunology Source Type: research

The need for change: Lessons learned from Food and Drug Administration-approved peanut oral immunotherapy
Ann Allergy Asthma Immunol. 2023 May;130(5):542-543. doi: 10.1016/j.anai.2023.01.031.NO ABSTRACTPMID:37137601 | DOI:10.1016/j.anai.2023.01.031
Source: Annals of Allergy, Asthma and Immunology - May 3, 2023 Category: Allergy & Immunology Authors: S Shahzad Mustafa Douglas P Mack Source Type: research

Asymptomatic surveillance testing for COVID-19 in health care professional students: lessons learned from a low prevalence setting
The novel coronavirus disease of 2019 (COVID-19) pandemic has severely impacted the training of health care professional students because of concerns of potential asymptomatic transmission to colleagues and vu...
Source: Allergy, Asthma and Clinical Immunology - March 29, 2023 Category: Allergy & Immunology Authors: Alyssa G. Burrows, Sophia Linton, Jenny Thiele, Prameet M. Sheth, Gerald A. Evans, Stephen Archer, Katharine M. Doliszny, Marcia Finlayson, Leslie Flynn, Yun Huang, Azim Kasmani, T. Hugh Guan, Allison Maier, Adrienne Hansen-Taugher, Kieran Moore, Anthony Tags: Short report Source Type: research

Why Evidence-Based Medicine Fans Could Use a Lesson in Persuasion Why Evidence-Based Medicine Fans Could Use a Lesson in Persuasion
Ravi B. Parikh, MD, MPP, explores the evidence-based oncology movement, which started off promising but transformed into takedowns of trials, investigators, and the FDA.Medscape Oncology
Source: Medscape Allergy Headlines - February 16, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology Commentary Source Type: news

Allergy to Omalizumab: Lessons from a Reaction to the Coronavirus 2019 Vaccine
Intern Med. 2023 Feb 1. doi: 10.2169/internalmedicine.1169-22. Online ahead of print.ABSTRACTOmalizumab can cause hypersensitivity reactions. We herein report the first case of an 18-year-old woman with refractory cough-predominant asthma that correlated with allergic reactions caused by omalizumab and the coronavirus disease 2019 (COVID-19) vaccine. The patient developed angioedema after taking omalizumab. She had previously experienced intense coughing immediately after receiving a COVID-19 vaccine. A skin prick test was positive for polysorbate 20, which was probably the cause of the allergic reactions to omalizumab and...
Source: Internal Medicine - February 1, 2023 Category: Internal Medicine Authors: Takeshi Matsumoto Yumiko Sakurai Takahiro Fujiki Yusuke Kusakabe Emi Nakayama Ayaka Tanaka Naoki Yamamoto Kensaku Aihara Shinpachi Yamaoka Michiaki Mishima Source Type: research

Tixagevimab-Cilgavimab Rollout on Common Variable Immunodeficient Patients: Early Lessons from an Academic Allergy and Immunology Clinic
Tixagevimab-cilgavimab is a combination of two monoclonal antibodies against SARS-CoV-2. In December 2021, the FDA issued emergency use authorization for intramuscular injection of tixagevimab-cilgavimab for prophylaxis against SARS-CoV-2 in immunocompromised patients. Shortly thereafter, our clinic distributed tixagevimab-cilgavimab to patients with Common Variable Immunodeficiency (CVID). To our knowledge, no prior study has looked at effects of this monoclonal antibody combination on CVID patients.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Daniela Dluzynski, Taha Al-Shaikhly, Maria Paula Henao Source Type: research

The Role of Quality Improvement in Allergy Practices
Over the past three years, Allergy/Immunology practices have faced unprecedented challenges due to the COVID-19 pandemic. This forced rapid and significant changes to the manner in which patient care was delivered and demonstrated adaptability, resiliency, and fortitude among clinicians.1 Unfortunately, it also contributed to widespread burnout, stress, and fatigue. There are many lessons to learn from the past few years and undoubtedly the strength of our specialty and powerful impact we have on our patients ’ lives will remain at the forefront of our mission moving forward.
Source: Annals of Allergy, Asthma and Immunology - December 17, 2022 Category: Allergy & Immunology Authors: David R. Stukus Tags: Perspective Source Type: research