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Infectious Disease: Aspergillosis

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Total 354 results found since Jan 2013.

Case Report: Antifungal Agents in the Treatment of Asthma and Allergy After Water-Damaged Building Exposure
Altern Ther Health Med. 2023 Jul 21:AT8331. Online ahead of print.ABSTRACTDamp and moisture-damaged building exposure has been linked to adverse health effects, primarily related to respiratory complications from mold spore reactions. This paper describes a case of a previously healthy man who was exposed to a home with hidden mold infestation and remained symptomatic following proper remediation. The patient presented with allergies, allergic bronchopulmonary aspergillosis, and treatment resistant asthma, as well as other non-respiratory symptoms likely related to inhalational mycotoxin exposure from his home. In this cas...
Source: Alternative Therapies in Health and Medicine - July 21, 2023 Category: Complementary Medicine Authors: Jill Crista Source Type: research

Disparity Between Mold Immunotherapy Dosing and Practice Parameter Recommendations in a Large Healthcare Setting.
Molds are ubiquitous, eukaryotic micro-organisms that reproduce from spores and belong to the Fungi kingdom. They have been implicated in a number of hypersensitivity disorders including asthma, allergic rhinitis, hypersensitivity pneumonitis, allergic bronchopulmonary aspergillosis, allergic fungal rhinosinusitis, and atopic dermatitis.1 Allergen immunotherapy (AIT) represents a potentially disease modifying therapy for individuals sensitized to mold, and its efficacy has been established for the treatment of allergic rhinitis and allergic asthma.
Source: Annals of Allergy, Asthma and Immunology - April 22, 2023 Category: Allergy & Immunology Authors: Christopher V. Macomb, Christopher S. Chavarria, Michael R. Nelson, Satyen M. Gada, David J. Schwartz Tags: Letters Source Type: research

Eosinophilic Lung Diseases
The eosinophilic lung diseases may manifest as chronic eosinophilic pneumonia, acute eosinophilic pneumonia, or as the L öffler syndrome (generally of parasitic etiology). The diagnosis of eosinophilic pneumonia is made when both characteristic clinical-imaging features and alveolar eosinophilia are present. Peripheral blood eosinophils are generally markedly elevated; however, eosinophilia may be absent at presentat ion. Lung biopsy is not indicated except in atypical cases after multidisciplinary discussion. The inquiry to possible causes (medications, toxic drugs, exposures, and infections especially parasitic) must be...
Source: Immunology and Allergy Clinics of North America - April 12, 2023 Category: Allergy & Immunology Authors: Vincent Cottin Source Type: research

Molecular epidemiology and antifungal susceptibilities of Aspergillus species isolated from patients with invasive aspergillosis
CONCLUSION: Accurate identification of strains and antifungal susceptibility studies should be performed due to azole and amphotericin B resistance. Genotyping studies are important in infection control due to identifying sources of infection and transmission routes.PMID:36820712 | PMC:PMC9937602 | DOI:10.1590/1806-9282.20220441
Source: Cancer Control - February 23, 2023 Category: Cancer & Oncology Authors: Fatma Mutlu Sarig üzel Ayse Nedret Ko ç P ınar Sağiroğlu Mustafa Altay Atalay Arda Borlu Özlem Canöz Bedia Din ç Source Type: research

Allergic Bronchopulmonary Aspergillosis in Patients with Dominant Negative IL6ST
We describe clinical characteristics of four patients with heterozygous IL6ST variants with presentations consistent with allergic bronchopulmonary aspergillosis (ABPA).
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Jennifer Roper, Sebastian Ochoa, Anahita Agharahimi, Justina Pfister, Magdalena Walkiewicz, Amanda Urban, Rajarshi Ghosh, Michail Lionakis, Lisa Kohn, Kenneth Olivier, Alexandra Freeman Source Type: research

The Difference in All-Cause Mortality Between Allergic Bronchopulmonary Aspergillosis with and without Chronic Obstructive Pulmonary Disease
Source: Journal of Asthma and Allergy - December 28, 2022 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Severe asthma with fungal sensitisation is associated with worse small airways dysfunction but similar symptom control
Severe asthma with fungal sensitisation (SAFS) is an allergic immune-mediated disorder existing on the spectrum between non-sensitised asthma and allergic bronchopulmonary aspergillosis (ABPA).1 Fungal sensitisation is associated with life-threatening acute asthma attacks requiring intensive care admissions and asthma-related deaths, and has a higher prevalence in patients severe asthma.2 Prospectively, it has been shown that IgE sensitisation to Aspergillus fumigatus is associated with worse lung function as forced expiratory volume in 1 second (FEV1), greater total IgE levels and a higher prevalence of A.
Source: Annals of Allergy, Asthma and Immunology - December 10, 2022 Category: Allergy & Immunology Authors: Rory Chan, Brian Lipworth Tags: Letters Source Type: research

Severe asthma with fungal sensitization is associated with worse small airway dysfunction but similar symptom control
Severe asthma with fungal sensitization (SAFS) is an allergic immune-mediated disorder existing on the spectrum between nonsensitized asthma and allergic bronchopulmonary aspergillosis (ABPA).1 Fungal sensitization is associated with life-threatening acute asthma attacks requiring intensive care admissions and asthma-related deaths, and it has a higher prevalence in patients with severe asthma.2 Prospectively, it has been found that immunoglobulin (Ig)E sensitization to Aspergillus fumigatus is associated with worse lung function as forced expiratory volume in 1 second (FEV1), greater total IgE levels, and a higher prevale...
Source: Annals of Allergy, Asthma and Immunology - December 10, 2022 Category: Allergy & Immunology Authors: Rory Chan, Brian Lipworth Tags: Letters Source Type: research

Clinico-demographic, radiological and immunological profile of allergic bronchopulmonary aspergillosis in a tertiary care institute of east India.
Conclusion: There was no significant association between lung function abnormalities and eosinophil count. ABPA-S was the most common finding among ABPA patients. High eosinophil count is associated with high incidence of bronchiectasis and hyper attenuated mucus (HAM) although severity of bronchiectasis is not directly related to higher peripheral eosinophil count. There may be some correlation between peripheral eosinophil count and total IgE but no significant correlation with aspergillus specific IgE.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Shankar, M., Ejazi, A., Chaubey, S., Kumar, D. Tags: 05.03 - Allergy and immunology Source Type: research

Can dose reduction be made in patients with allergic bronchopulmonary aspergillosis receiving high-dose omalizumab treatment?
Conclusions. Decreasing the total omalizumab dose does not cause clinical deterioration in ABPA after the disease is controlled.PMID:35850503 | DOI:10.23822/EurAnnACI.1764-1489.261
Source: European Annals of Allergy and Clinical Immunology - July 19, 2022 Category: Allergy & Immunology Authors: E T Korkmaz O Ayd ın D Mungan B A Sin Y S Demirel S Bavbek Source Type: research