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Total 453 results found since Jan 2013.
Citrin: a novel food allergen in citrus seeds and citrus-derived pectin that shows cross-reactivity with cashew and pistachio
CONCLUSION: Citrus pectin may be contaminated with citrus seeds. Citrin, a newly identified allergen in citrus seeds, appears to be the culprit antigen in citrus seeds and contaminated citrus pectin. Citrin is highly homologous with Ana o 2 in cashew and Pis v 2 in pistachio, suggesting potential for cross-reactivity and providing an explanation for co-allergenicity of cashew/pistachio, citrus seeds, and citrus pectin.PMID:37659472 | DOI:10.1016/j.anai.2023.08.603
Source: Annals of Allergy, Asthma and Immunology - September 2, 2023 Category: Allergy & Immunology Authors: George N Konstantinou Mary Grace Baker Joyce Yu Lara S Ford Ramon Bencharitiwong Galina Grishina Hugh Sampson Scott Sicherer Anna Nowak-Wegrzyn Source Type: research
The reason and mechanism of propylene glycol alginate sodium sulfate (PSS) mediated allergic side effect
Int J Biol Macromol. 2023 Apr 27:124638. doi: 10.1016/j.ijbiomac.2023.124638. Online ahead of print.ABSTRACTPropylene glycol alginate sodium sulfate (PSS) is a heparinoid polysaccharide drug used in clinic for >30 years in China. But its allergy events happened from time to time and should not be ignored. Here, ammonium salt in PSS (PSS-NH4+), PSS fractions with high Mw (PSS-H-Mw) and low mannuronic acid (M) to guluronic acid (G) ratio (PSS-L-M/G) were found to induce allergic response by the structure-activity and impurity-activity relationships in vitro. Furthermore, we confirmed the reason and elucidated the mechanis...
Source: International Journal of Biological Macromolecules - April 29, 2023 Category: Biochemistry Authors: Yi-Ting Xue Shuang Li Xin-Yang Jiang Meng Xin Hai-Hua Li Guang-Li Yu Xiao-Xi He Chun-Xia Li Source Type: research
Continuous ingestion of sodium chloride solution promotes allergen absorption and may exacerbate allergy symptoms on ovalbumin-induced food allergy in mice
In this study, we investigated the effect of continuous ingestion of sodium chloride (NaCl) on allergy symptoms using a mouse model of food allergy. BALB/c mice were divided into four groups of 6-8 animals each. The control-water group (CW) and sensitization-water group (SW) groups were provided free access to water, and the control-1% NaCl group (CS) and sensitization-1% NaCl group (SS) groups were provided a 1% NaCl solution. The SW and SS groups were sensitized with 50 µg ovalbumin (OVA) at 2 timepoints by intraperitoneal injection. After oral administration of OVA, anaphylactic response was measured and blood was coll...
Source: Drug Discoveries and Therapeutics - February 27, 2023 Category: Drugs & Pharmacology Authors: Mamoru Tanaka Rui Lu Hana Kozai Source Type: research
Oral detergent exposure alters the esophageal microbiome and induces eosinophilic inflammation
Detergent exposure is a possible environmental factor recently implicated in the pathogenesis of eosinophilic esophagitis (EoE). We have shown the detergent sodium dodecyl sulfate (SDS) induces epithelial barrier dysfunction and eosinophilic inflammation in mice. We aimed to examine changes in the mouse esophageal microbiome following SDS exposure.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Benjamin Wright, Mia Masuda, Samuel Flashner, Jessica Gibson, Huijun Luo, Arina Putikova, Grace Pyon, Matthew Rank, Hiroshi Nakagawa, Hirohito Kita, Emily Cope, Alfred Doyle Source Type: research
Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
