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Specialty: Infectious Diseases

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Total 742 results found since Jan 2013.

Human PLCG2 Haploinsufficiency Results in a Novel NK Cell Immunodeficiency
CONCLUSIONS: PLCG2 haploinsufficiency represents a distinct syndrome from previous variants characterized by NK cell immunodeficiency with herpes virus susceptibility, expanding the spectrum of PLCG2-related disease.PMID:37714437 | DOI:10.1016/j.jaci.2023.09.002
Source: Herpes - September 15, 2023 Category: Infectious Diseases Authors: Joshua B Alinger Emily M Mace Justin R Porter Annelise Y Mah-Som Allyssa L Daugherty Stephanie Li Allison A Throm Jeanette T Pingel Nermina Saucier Albert Yao Ivan K Chinn James R Lupski Mohammad Ehlayel Michael Keller Greg R Bowman Megan A Cooper Jordan Source Type: research

Toxoplasmosis mimicking CMV chorioretinitis in newly diagnosed PLWH: a case report
CONCLUSIONS: despite progressive developments in the management of PLWH, in this case two different kind of opportunistic infection are found in a late-presenter patient. In particular, two aspects can be highlighted. The first one is that, in the setting of an highly impaired immune system, clinical presentation can be deceptive and more than one opportunistic infection can be observed together in the same patient. The second aspect is that after starting antiretroviral therapy, a rapid improvement of viro-immunologic parameters has been documented, probably leading to an immune reconstitution inflammatory syndrome (IRIS)...
Source: Infezioni in Medicina - September 13, 2023 Category: Infectious Diseases Authors: Francesco Lamanna Rosa Anna Passerotto Andrea Carbone Rebecca Jo Steiner Valentina Iannone Pierluigi Francesco Salvo Arturo Ciccullo Gianmaria Baldin Alberto Borghetti Alex Dusina Source Type: research

Dupilumab strengthens HSV-1 specific immune responses in atopic dermatitis
CONCLUSION: Our findings suggest that dupilumab may improve the HSV-1-specific immune response in AD due to an increased type I immune response and a reduction of HSV-1-specific IgE.PMID:37660986 | DOI:10.1016/j.jaci.2023.08.024
Source: Herpes - September 3, 2023 Category: Infectious Diseases Authors: Stephan Traidl Leonard Harries Petra Kienlin Gabriele Begemann Lennart M Roesner Thomas Werfel Source Type: research

The role of food allergy as a provoking factor of migraine
CONCLUSION: We show for the first time the relationship between delayed-type food allergy and redistribution in the microbiome of the oropharynx of patients with migraine and once again confirm the role of delayed-type food allergy as a clinically significant factor influencing the course of migraine (its intensity and chronicity).PMID:37655411 | DOI:10.17116/jnevro202312308156
Source: Herpes - September 1, 2023 Category: Infectious Diseases Authors: I L Naidenova A B Danilov A V Simonova A A Pilipovich E G Filatova Source Type: research

Stevens-johnson Syndrome and Toxic Epidermal Necrolysis: An Overview of Diagnosis, Therapy Options and Prognosis of Patients
Recent Adv Inflamm Allergy Drug Discov. 2023 Aug 21. doi: 10.2174/2772270817666230821102441. Online ahead of print.ABSTRACTBoth Stevens-Johnson syndrome (SJS) and Toxic-epidermal necrolysis (TEN) are generally medication-induced pathological conditions that mostly affect the epidermis and mucus membranes. Nearly 1 to 2 patients per 1,000,000 population are affected annually with SJS and TEN, and sometimes these maladies can cause serious life-threatening events. The reported death rates for SJS range from 1 to 5%, and 25 to 35% for TEN. The mortality risk may even be higher among elderly patients, especially in those who a...
Source: Herpes - August 22, 2023 Category: Infectious Diseases Authors: Vivek Kumar Garg Harpal S Buttar Sajad Ahmad Bhat Nuftieva Ainur Tannu Priya Dharambir Kashyap Hardeep Singh Tuli Source Type: research

Penicillin Allergy Impact and Management
There is international evidence that penicillin allergies are associated with inferior prescribing and patient outcomes. A host of tools now exist from assessment (risk assessment tools, clinical decision rules) to delabeling (the removal of a beta-lactam allergy via testing or medical reconciliation) to reduce the impact of these “labels” in the hospital and community setting, as a primary antimicrobial stewardship intervention.
Source: Infectious Diseases Clinics of North America - August 1, 2023 Category: Infectious Diseases Authors: Rebekah H. Wrenn, Jason A. Trubiano Source Type: research

Leflunomide Induced Atypical DRESS: A Case Report and Literature Review
We report a case of a lady aged 32 years, presented to our hospital with a history of leflunomide intake and symptoms of DRESS.PMID:37223589 | PMC:PMC10201105 | DOI:10.31138/mjr.34.1.91
Source: Herpes - May 24, 2023 Category: Infectious Diseases Authors: Maryam Fatima Salwa Sahar Azimi Soumya Ashwini Madhuri H Radhakrishna Source Type: research