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A Meta-Analysis of the Ability of Exercise to Reduce Age-Related Mortality
The objective of this study was to conduct a systematic review and dose-response meta-analysis of physical activity and mortality in people with selected non-communicable diseases (NCDs). We aimed to define the dose-response relationship between post-diagnosis physical activity and mortality rates for nine NCDs with a high global burden of disease, including low back pain, type 2 diabetes (T2D), osteoarthritis, depressive disorder, chronic obstructive pulmonary disease (COPD), breast cancer, lung cancer, stroke, and ischemic heart disease (IHD). In total, 28 studies were included in the meta-analysis: 12 for breast ...
Source: Fight Aging! - September 10, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Proposed guidelines likely to identify more early lung cancers
Lung cancer is the second most prevalent cancer in the US, and the deadliest cancer killer. In 2020, an estimated 135,720 people will die from the disease — more than breast, colon, and prostate cancers combined. I’ll never forget meeting new, advanced-stage lung cancer patients who ask if their diagnosis could have somehow been made earlier, when treatment would have been more likely to succeed. In 2009, when I began practicing thoracic oncology, there were no approved screening tests for lung cancer. A brief history of lung cancer screening Hope for early detection and death prevention came in 2011 with the publicati...
Source: Harvard Health Blog - September 9, 2020 Category: Consumer Health News Authors: Inga Lennes, MD, MPH, MBA Tags: Cancer Lung disease Screening Source Type: blogs

Clearing the misinformation surrounding medical cannabis
An excerpt from Medical Marijuana: A Clinical Handbook. Imagine two patients sitting in the waiting area of a clinic. The first is a man in his sunset years who has recently begun treatment for stage 2 lung cancer. His treatment involves the use of chemotherapy, which has significantly reduced his appetite and given him terrible […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - September 6, 2020 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/samoon-ahmad-and-kevin-hill" rel="tag" > Samoon Ahmad, MD and Kevin Hill, MD < /a > < /span > Tags: Meds Psychiatry Source Type: blogs

Fight Aging! Newsletter, September 7th 2020
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Assessing the Utility of Six of the Better Known Epigenetic Clocks in a Large Study Population
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 4, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Does air pollution cause Alzheimer ’s disease?
Have you ever spent the day in a city with such bad air pollution that when you blew your nose the mucus had a black tinge? Have you ever coughed as you breathed in diesel fumes from a passing bus and thought to yourself, “Well, that’s a year gone from my life”? Could it actually be true — that air pollution leads to an early death? The answer, in fact, is an unqualified yes. Air pollution causes heart disease, lung disease, and early death It has been known for some time that air pollution causes lung cancer, chronic obstructive pulmonary disease, emphysema, asthma, heart disease, and stroke. One recent study in C...
Source: Harvard Health Blog - July 23, 2020 Category: Consumer Health News Authors: Andrew E. Budson, MD Tags: Alzheimer's Disease Environmental health Healthy Aging Memory Neurological conditions Source Type: blogs

Podcast: Life with Binge Eating Disorder
  At one point, Gabe weighed more than 550 pounds. Today, he and Lisa remember and discuss the extreme pain and slow healing process of living with binge-eating disorder. Gabe shares his shame in being so overweight, his intense relationship with food, the story of his gastric bypass and the difficult process of learning new coping mechanisms. How did Gabe’s bipolar and panic attacks tie in with his binge eating? And, importantly, how is he managing the illness today? Join us for an open and honest discussion on living with an eating disorder. (Transcript Available Below) Please Subscribe to Our Show: And We Lov...
Source: World of Psychology - July 21, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Binge Eating Disorders Eating Disorders General Not Crazy Podcast Source Type: blogs

This patient has a severe electrolyte abnormality. Can you tell what it is? (Not hypokalemia)
This patient has a severe electrolyte abnormality.  Can you tell from the ECG what it is?IMPRESSION by computer and physician overread:Heart Rate 120SINUS TACHYCARDIA WITH FIRST DEGREE AV BLOCKPOSSIBLE LEFT ATRIAL ENLARGEMENT [-0.1mV P WAVE IN V1/V2]MODERATE ST DEPRESSION [0.05+ mV ST DEPRESSION]Prolonged QTABNORMAL ECGP-R Interval 220 msQRS Interval 84 msQT Interval 349 ms QTC Interval 419 msP Axis 125QRS Axis 13T Wave Axis 2I think the computer got the QT wrong.  It is at least 360 ms and possibly as high as 400 ms.Hodges Corrections using 360 ms: QTc = 465 msSmith Impression: The ECG shows ...
Source: Dr. Smith's ECG Blog - June 30, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

Podcast: Is Addiction a Disease?
  What is the link between addiction and mental illness? Is addiction a choice? In today’s Not Crazy podcast, Gabe and Lisa discuss whether addiction should be classified as a disease and whether or not it should require medical treatment. Gabe also shares his personal story of addiction and how it tied in with his bipolar disorder. What’s your take? Tune in for an in-depth discussion which covers every angle of this often controversial topic. (Transcript Available Below) Please Subscribe to Our Show: And We Love Written Reviews!  About The Not Crazy podcast Hosts Gabe Howard is an award-winning writer ...
Source: World of Psychology - June 23, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Addiction General Mental Health and Wellness Not Crazy Podcast Recovery Source Type: blogs

Processing Your Baggage
In the later years of Walt Disney’s life, he actively worked on his vision for EPCOT (Experimental Prototype Community of Tomorrow). His intention was to build a complete city of the future – a place for people to live and work in harmony. His designs included a central downtown hub with skyscrapers, Monorails and People Movers for transportation, houses for people to live in, entertainment centers, parks, waste management, and more. It was a big picture vision that he’d been working on for many years, including a deep study of urban planning. When Walt died his EPCOT vision unfortunately died with him. No...
Source: Steve Pavlina's Personal Development Blog - June 14, 2020 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Health Lifestyle Source Type: blogs

Detection dogs
There was an interview on BBC Breakfast last week with a detection dog, or, strictly, with someone fromMedical Detection Dogs, accompanied by a detection dog.  Dogs have been used to " sniff out " malaria and Parkinson ' s, and there are investigations into whether they can be trained to detect COVID-19.There are details of that trial, which involves the University of Durham, the London School of Hygiene and Tropical Medicine, and Medical Detection Dogs,on this Government webpage. So what is in the literature?   A PubMed search for detection dog finds some papers, but also a lot about detecting thi...
Source: Browsing - May 24, 2020 Category: Databases & Libraries Source Type: blogs

And now for some good news on health
When it comes to health concerns, the COVID-19 pandemic is top of mind for most people right now. And that’s for good reason. But there is some very good non-COVID health news that may not be getting the attention it deserves. According to the CDC, the rates of six of the top 10 causes of death in this country, which account for about three-quarters of all deaths, have been declining. That’s remarkable. And these improvements are occurring despite an aging population and an obesity epidemic that affects several health conditions. Six positive health trends Let’s look at the trends in these conditions and their rank ...
Source: Harvard Health Blog - May 15, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Cancer Health Health trends Heart Health Source Type: blogs

Parent's Decision Not To Be Treated for Cancer Upsets Daughter
Photo credit Aaron Andrew Dear Carol: There’s probably no right answer to what I’m asking but I felt the need to write just for comfort. My mother died when I was in my teens, so Dad has been the only parent that I’ve had for more than 20 years. I have no siblings. Dad’s now in his 70s and has been diagnosed with prostate cancer. He’s beaten both melanoma and lung cancer in the past, but he tells me that this cancer should be slow-growing and that he’ll probably die before it’s a problem so he doesn’t want to treat it. I want him to go full-on with every treatment possible. I watched both of my parents figh...
Source: Minding Our Elders - May 14, 2020 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Private Good Deeds That Appear To Compensate For Bad Public Behaviour Make People Seem Hypocritical
By Emma Young It’s hard to find a clearer example of moral hypocrisy than this: in 2015, Josh Duggar, a family values activist and director of a lobby group set up “to champion marriage and family as the foundation of civilisation, the seedbed of virtue, and the wellspring of society” was outed as holding an account with a dating service for people who are married or in relationships. As Kieran O’Connor at the University of Virginia and colleagues point out in a new paper in the Journal of Personality and Social Psychology: Attitudes and Social Cognition, Duggar’s apparently virtuous public image was in stark co...
Source: BPS RESEARCH DIGEST - May 13, 2020 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Morality Social Source Type: blogs

Looking past the pandemic: Could building on our willingness to change translate to healthier lives?
If the COVID-19 pandemic has taught us anything, it’s that people have the capacity to change entrenched behaviors when the stakes are high enough. Who among us declared that 2020 would be the year for us to perfect the practice of physical distancing? Although we were clueless about pandemic practices a mere three months ago, we’ve adopted this new habit to avoid getting or spreading the virus. But what about other unhealthy behaviors that have the potential to shorten life spans across the US? On January 1, 2020, some of us made New Year’s resolutions aimed at improving our health: to eat less, lose weight, exercis...
Source: Harvard Health Blog - April 28, 2020 Category: Consumer Health News Authors: Steven A. Adelman, MD Tags: Addiction Behavioral Health Healthy Aging Healthy Eating Heart Health Source Type: blogs