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Cholesterol and breast cancer
All these new studies, or at least one which was noticed by the media who are in the process of over-hyping it, tell us that cholesterol 'fuels' breast cancer. Well, woop-de-doo I say. This is one of those things that I figure I can ignore.My doctors have said my good cholesterol was nice and high and my bad cholesterol was nice and low with a total number that was just about right. But now they say my cholesterol could have helped cause my breast cancer.I am confused. For decades we are told low bad cholesterol for heart health, blah, blah, blah. Now its fueling breast cancer? What are we supposed to do, give up eating? O...
Source: Caroline's Breast Cancer Blog - December 3, 2013 Category: Cancer Tags: cancer cause cancer research Source Type: blogs
Cancer Survivors Exhibit a Significantly Higher Risk of Cardiovascular Disease
The dominant cancer therapies of chemotherapy and radiotherapy have not yet been replaced by immunotherapies for more than a handful of cancer types. These classes of therapy produce a significantly increased burden of senescent cells in patients; one of the goals of cancer therapy is to drive cancerous cells into senescence, those that cannot be killed. These additional senescent cells in turn accelerate the progression of degenerative aging. The advent of senolytic therapies to clear senescent cells from aged tissues will make a sizable difference to these patients. More effort should be undertaken today to enable patien...
Source: Fight Aging! - July 4, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
If PSA Tests Don't Impact Survival, Why Do Insurance Companies Do The Test Without Your Knowledge?
A discussion on Twitter caught the eyes of my colleagues yesterday, and raised a very interesting question: should insurance companies be allowed to do PSA testing to detect prostate cancer on men as a condition of getting insurance?
What started the discussion was a blog post by a well-known and respected medical blogger who goes by the name "Skeptical Scalpel." In his blog he detailed the saga of a 56 year old man who had a pre-employment physical in order to be covered by his new company's health insurance plan. He was not informed that he was going to have a PSA test. It was just done as part of the process. No informe...
Source: Dr. Len's Cancer Blog - August 21, 2013 Category: Cancer Authors: Dr. Len Tags: Cancer Care Early detection Prostate Cancer Screening Survivors Treatment Source Type: blogs
Beyond heart health: Could your statin help prevent liver cancer?
Liver cancer is hard to treat. It’s a top-five cause of cancer-related death worldwide and a growing cause of cancer-related deaths in the United States. Since liver cancer is often found at a late stage, when treatment has limited benefit, there has been increasing interest in prevention. That’s where statin medications might come in.
Liver cancer is usually caused by chronic liver disease, so an important way to prevent liver cancer is to treat the underlying trigger. For example, curing hepatitis C infection — an important cause of chronic liver disease — reduces the risk of liver cancer. However, if the liver d...
Source: Harvard Health Blog - January 27, 2020 Category: Consumer Health News Authors: Irun Bhan, MD Tags: Cancer Drugs and Supplements Health Source Type: blogs
Long-term statin use protects against prostate cancer death
Statins and other drugs that lessen cardiovascular disease risk by lowering blood lipids rank among the world’s most prescribed medications. And for the men who take them, accumulating evidence has for years pointed to another added benefit: a lower risk of developing prostate cancer.
Now researchers are reporting that long-term statin use (more than 10 years) can also reduce the odds of a prostate cancer death. The new findings come from a study led by Alison Mondul, a cancer epidemiologist at the University of Michigan School of Public Health.
Mondul says that most men develop slow-growing, indolent prostate cancers th...
Source: Harvard Health Blog - January 7, 2019 Category: Consumer Health News Authors: Charlie Schmidt Tags: Living With Prostate Cancer Prostate Knowledge HPK Source Type: blogs
Heart disease and breast cancer: Can women cut risk for both?
Very often I encounter women who are far more worried about breast cancer than they are about heart disease. But women have a greater risk of dying from heart disease than from all cancers combined. This is true for women of all races and ethnicities. Yet only about 50% of women realize that they are at greater risk from heart disease than from anything else.
Currently in the US, three million women are living with breast cancer, which causes one in 31 deaths. Almost 50 million women have cardiovascular disease, which encompasses heart disease and strokes and causes one in three deaths.
Here’s what’s really interestin...
Source: Harvard Health Blog - January 8, 2019 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Breast Cancer Exercise and Fitness Health Healthy Eating Heart Health Women's Health Source Type: blogs
And so it begins: Breast Cancer Awareness Month brings out the cancer quacks
As I mentioned yesterday, here it’s that time of year again: October. Breast Cancer Awareness Month. While the topic of my post then was how antivaccine activists have tried to glom on to the attention that Breast Cancer Awareness Month gets in order to create their fake “awareness month” known as “Vaccine Injury Awareness Month,”…
Source: Respectful Insolence - October 2, 2014 Category: Surgery Authors: Orac Tags: Cancer Complementary and alternative medicine Quackery Bernd Klein breast cancer cholesterol cleanse German New Medicine Kevin Trudeau Leonard Coldwell raw vegan Robert O. Young Source Type: blogs
Diet and exercise limit heart disease risk in men undergoing hormonal treatments for advanced prostate cancer
Men with advanced prostate cancer are typically treated with drugs that prevent the body from making or using testosterone. A hormone (or an androgen, as it’s known), testosterone drives prostate cancer cells to grow faster, so shutting it down is essential to keeping the illness in check. About 600,000 men with advanced prostate cancer in the United States today are undergoing this type of anti-hormonal treatment, which is called androgen deprivation therapy (ADT). But even as ADT helps men live longer, it exerts a toll on the body. Men can lose muscle and bone mass, gain weight, and they face higher risks for heart dis...
Source: Harvard Health Blog - February 25, 2019 Category: Consumer Health News Authors: Charlie Schmidt Tags: Health Living With Prostate Cancer Prostate Knowledge Treatments HPK Source Type: blogs
Fight Aging! Newsletter, January 4th 2021
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - January 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, July 31st 2023
In conclusion, an SBP level below 130 mmHg was found to be associated with longevity among older women. The longer SBP was controlled at a level between 110 and 130 mmHg, the higher the survival probability to age 90. Preventing age-related rises in SBP and increasing the time with controlled BP levels constitute important measures for achieving longevity.
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Source: Fight Aging! - July 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, September 20th 2021
In conclusion, inhibiting the lysosomal oxidation of LDL in atherosclerotic lesions by antioxidants targeted at lysosomes causes the regression of atherosclerosis and improves liver and muscle characteristics in mice and might be a promising novel therapy for atherosclerosis in patients.
NANOG Expression versus Cellular Senescence
https://www.fightaging.org/archives/2021/09/nanog-expression-versus-cellular-senescence/
Are there many strategies that can reverse cellular senescence? There are certainly strategies that can lower levels of cellular senescence over time, both in cell cultures and in living an...
Source: Fight Aging! - September 19, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, July 11th 2022
In this study we employ a transcriptome-wide and multi-tissue approach to analyze the influence of both LTDR and short-term DR (STDR) at old age on the aging phenotype. We were able to characterize a common transcriptional gene network driving inflammaging in most of the analyzed tissues. This network is characterized by chromatin opening and upregulation in the transcription of innate immune system receptors and by activation of interferon signaling through interferon regulatory factors, inflammatory cytokines, and Stat1-mediated transcription. We also found that both DR interventions ameliorate this inflammaging phenotyp...
Source: Fight Aging! - July 10, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, May 18th 2020
This study provides direct evidence for the contribution of gut microbiota to the cognitive decline during normal aging and suggests that restoring microbiota homeostasis in the elderly may improve cognitive function.
On Nutraceutical Senolytics
https://www.fightaging.org/archives/2020/05/on-nutraceutical-senolytics/
Nutraceuticals are compounds derived from foods, usually plants. In principle one can find useful therapies in the natural world, taking the approach of identifying interesting molecules and refining them to a greater potency than naturally occurs in order to produce a usefully large therape...
Source: Fight Aging! - May 17, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, August 16th 2021
In conclusion, cancer survivors, especially older individuals, demonstrate greater odds of and accelerated functional decline, suggesting that cancer and/or its treatment may alter aging trajectories.
Linking Particulate Air Pollution and Dementia in a Small Region of the US
https://www.fightaging.org/archives/2021/08/linking-particulate-air-pollution-and-dementia-in-a-small-region-of-the-us/
It is fairly settled that evident particulate air pollution, such as daily exposure to smoke from wood-fueled cooking fires, has a strongly detrimental effect on long-term health. The mechanisms involved are inflamm...
Source: Fight Aging! - August 15, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, June 6th 2016
This study teaches us that poor wound healing and wrinkling and sagging that occur in aging skin share similar mechanisms."
Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin
Human skin heals more slowly in aged vs. young adults, but the mechanism for this delay is unclear. In humans, eccrine sweat glands (ESGs) and hair follicles underlying wounds generate cohesive keratinocyte outgrowths that expand to form the new epidermis. Our results confirm that the outgrowth of cells from ESGs is a major feature of repair in young skin. Strikingly, in aged skin, ...
Source: Fight Aging! - June 5, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
