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Artificial Intelligence vs. Tuberculosis, Part 1
By SAURABH JHA, MD
Slumdog TB
No one knows who gave Rahul Roy
tuberculosis. Roy’s charmed life as a successful trader involved traveling in his
Mercedes C class between his apartment on the plush Nepean Sea Road in South
Mumbai and offices in Bombay Stock Exchange. He cared little for Mumbai’s weather.
He seldom rolled down his car windows – his ambient atmosphere, optimized for
his comfort, rarely changed.
Historically TB, or
“consumption” as it was known, was a Bohemian malady; the chronic suffering produced
a rhapsody which produced fine art. TB was fashionable in Victorian Britain, in
part, because c...
Source: The Health Care Blog - December 5, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Saurabh Jha TB tuberculosis Source Type: blogs
Fight Aging! Newsletter, September 23rd 2019
Discussion of Developmental Effects on Aging
Microtubule Function and Longevity in Nematodes
Quantifying the Correlation Between Poverty and Faster Pace of Aging
Matthew O'Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019
https://www.fightaging.org/archives/2019/09/matthew-oconnor-presenting-on-underdog-pharmaceuticals-at-undoing-aging-2019/
Here Matthew O'Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atheroscleros...
Source: Fight Aging! - September 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, July 29th 2019
In this study we show, for the first time, significant alterations in cholesterol efflux capacity in adolescents throughout the range of BMI, a relationship between six circulating adipocyte-derived EVs microRNAs targeting ABCA1 and cholesterol efflux capacity, and in vitro alterations of cholesterol efflux in macrophages exposed to visceral adipose tissue adipocyte-derived EVs acquired from human subjects. These results suggest that adipocyte-derived EVs, and their microRNA content, may play a critical role in the early pathological development of ASCVD.
Commentary on the Developing UK Government Position on Hea...
Source: Fight Aging! - July 28, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Commentary on the Developing UK Government Position on Healthy Longevity
One option for patient advocacy for the treatment of aging as a medical condition is to petition governments and large international organizations such as the World Health Organization to adjust their positions on research funding and goals in medicine. This a fairly popular path, for all that I think it not terribly effective at speeding up the cutting edge of research and development. Large organizations of any sort are inherently conservative, and tend to get meaningfully involved in new fields of human endeavor only long after their support would have been truly influential.
Nonetheless, numerous examples of gov...
Source: Fight Aging! - July 26, 2019 Category: Research Authors: Reason Tags: Politics and Legislation Source Type: blogs
ProFound AI for 2D Mammography Cleared in Europe to Spot Potential Breast Tumors
iCAD, a company based in Nashua, New Hampshire, won European CE Mark approval for its ProFound AI for 2D Mammography software system.
The product relies on a “high-functioning, deep learning” artificial intelligence algorithm to a...
Source: Medgadget - July 16, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Ob/Gyn Radiology Surgery Source Type: blogs
Fight Aging! Newsletter, July 8th 2019
In this study, we identify a link between members of the genus Veillonella and exercise performance. We observed an increase in Veillonella relative abundance in marathon runners postmarathon and isolated a strain of Veillonella atypica from stool samples. Inoculation of this strain into mice significantly increased exhaustive treadmill run time.
Veillonella utilize lactate as their sole carbon source, which prompted us to perform a shotgun metagenomic analysis in a cohort of elite athletes, finding that every gene in a major pathway metabolizing lactate to propionate is at higher relative abundance postexercise. Us...
Source: Fight Aging! - July 7, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
From Chernobyl To Mars: The Future Of Radiation Protection
In the minutes after block 4 of the nuclear power
plant in Chernobyl exploded, no one knew that they are experiencing a disaster
that never happened anywhere before on planet Earth. The public health,
environmental, and even the socio-political consequences were disastrous and we
can still experience the negative impacts. That’s why we posed the question of
what public health authorities, as well as individuals, can do to mitigate the
consequences of radiation exposure, and what digital technologies are available
for radiation detection. In this respect, after our investigations, it even
turned out that it would be benef...
Source: The Medical Futurist - June 29, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Space Medicine astronautics chernobyl disaster fiction Health Healthcare Innovation mars nuclear power plant public health radiation radiation exposure radiation protection technology Source Type: blogs
Digital Skin Care: Top 8 Dermatology Apps
Each year 2-3 million non-melanoma and 132,000
melanoma skin cancers occur globally according to statistics from the
WHO. Thus, every tool has to be deployed for early detection and
intervention. As smartphone penetration already reached the quarter of the
Earth’s population, smartphone apps seem to be a viable way to go against skin
conditions. Here, we collected the top dermatology apps to aid your digital
skin care.
As smartphones take over the world, dermatology apps
multiply
As technology continues to advance, so too does its
accessibility to the general population. In 2013, only 56 percent of Americans
owned ...
Source: The Medical Futurist - June 4, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Telemedicine & Smartphones dermatology Health Healthcare Innovation patient patient information skin smart health smart healthcare smartphone apps technology Source Type: blogs
I see you –– but don’t ask me how I’m doing
On the worst day of my life, I noticed how many times an hour Americans ask some version of “how’s it going?” without actually wanting to know the answer. It happens when we pass each other in the halls at work, at the park, in line at Starbucks. We ask when making small talk before getting down to business.
It even happens when we are waiting for the test results that reveal we have cancer.
How’s it going?
On January 19, 2018, I parried that question five or six times before one of my best friends at the office asked it. It felt like I would be lying to not answer.
“This week, man—”
But I had to stop. How do...
Source: Harvard Health Blog - June 4, 2019 Category: Consumer Health News Authors: Adam P. Stern, MD Tags: Cancer Health Mental Health Relationships Source Type: blogs
Fight Aging! Newsletter, May 20th 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - May 19, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Healthcare In Estonia: Where Grandmas Go For Genetic Data
Imagine a country where citizens will have their genetic profiles integrated into the digital health system with individual risk scores and pharmacogenomic information, so when they go to the doctor, they will get fully personalized, genetic risk-based diagnosis, medication, and preventive measures. That’s where healthcare in Estonia will arrive soon. They started to build their digital health system 20 years ago, and within the next years, the Baltic country will start to reap the benefits of a transparent, blockchain-based, digital health system hooked on genetic data. The first fully digitized republic certainly sets ...
Source: The Medical Futurist - May 16, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Healthcare Policy analysis digital digital democracy digital health digital health strategy digital health system digital healthcare Estonia genetics genomics personalized Personalized medicine pharmacogenomi Source Type: blogs
Anethole Trithione is a Mitochondrial ROS Blocker
Mitochondria, the power plants of the cell, generate reactive oxygen species (ROS) as a side effect of the energetic operations needed to package fuel supplies used by cellular processes. While ROS are necessary signals in many physiological circumstances, such as the beneficial reaction to exercise, excessive ROS generation can be harmful. Excessive ROS generation is also observed in aging. Suppressing that excessive ROS flux at its source, without affecting the beneficial signaling roles, has been demonstrated to be beneficial in disease states characterized by inflammation and high degrees of oxidative stress. It may al...
Source: Fight Aging! - May 14, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, May 13th 2019
In this study, a significant (30%) increase in maximum lifespan of mice was found after nonablative transplantation of 100 million nucleated bone marrow (BM) cells from young donors, initiated at the age that is equivalent to 75 years for humans. Moreover, rejuvenation was accompanied by a high degree of BM chimerism for the nonablative approach. Six months after the transplantation, 28% of recipients' BM cells were of donor origin. The relatively high chimerism efficiency that we found is most likely due to the advanced age of our recipients having a depleted BM pool.
In addition to the higher incorporation rates, ...
Source: Fight Aging! - May 12, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, April 22nd 2019
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - April 21, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Microbial Signature for Colorectal Cancer Identified Using Machine Learning
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, the University of Trento in Italy, and other international collaborators leveraged a machine learning algorithm to identify a subset of gut bacteria associated ...
Source: Medgadget - April 17, 2019 Category: Medical Devices Authors: Siavash Parkhideh Tags: Genetics GI Informatics Oncology Pathology Source Type: blogs
