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A Combination of Situational and Anticipatory Greif Understandable Caregiver Emotions
Photo credit Danie Franco
Dear Carol: While my dad has suffered due to a stroke and subsequent vascular dementia, it’s cancer that’s killing him. Hospice care has been a blessing, but watching this once large, hearty man waste away is devasting. Even though Dad mostly sleeps, I can see the emotional suffering in his face during the brief times he does wake. I long for this to end yet I’m desperate not to lose him. I ask myself what purpose is served with so much suffering and it strains my faith. How do people cope with these complicated feelings? – HD
Continue reading in Inforum about these different types and how...
Source: Minding Our Elders - March 20, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
A Combination of Situational and Anticipatory Grief Understandable Caregiver Emotions
Photo credit Danie Franco
Dear Carol: While my dad has suffered due to a stroke and subsequent vascular dementia, it’s cancer that’s killing him. Hospice care has been a blessing, but watching this once large, hearty man waste away is devasting. Even though Dad mostly sleeps, I can see the emotional suffering in his face during the brief times he does wake. I long for this to end yet I’m desperate not to lose him. I ask myself what purpose is served with so much suffering and it strains my faith. How do people cope with these complicated feelings? – HD
Continue reading in Inforum about these different types and how...
Source: Minding Our Elders - March 20, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Incontinence from Prostate Cancer Surgery Acceptable Trade-off for John T
John T's family history included a number of men who developed prostate cancer so when he started having issues with dribbling due to bladder leaks, he watched cautiously and eventually sought medical help. His doctor ordered several PSA tests over time and eventually, John began seeing a urologist. He was diagnosed with prostate cancer and had surgery that left him with incontinence issues. No one wants this result, but he's learned to live with his incontinence - with gratitude.
Read John T's story on Egosancares blog for inspiration if you or someone you love may be facing prostate surgery:
Discover the Differenc...
Source: Minding Our Elders - March 17, 2022 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Fight Aging! Newsletter, February 28th 2022
In conclusion, as BMI and waist circumference are related to elevations of immune markers in the IL-6 pathway, chronic inflammation might be an important mediator of the relationship between BMI and frailty.
Fat Tissue Becomes Dysfunctional with Age as Mitochondria Falter
https://www.fightaging.org/archives/2022/02/fat-tissue-becomes-dysfunctional-with-age-as-mitochondria-falter/
Mitochondria are effectively power plants, hundreds of them working in every cell to produce chemical energy store molecules to power cellular processes. Mitochondrial function declines with age, unfortunately, for underlying re...
Source: Fight Aging! - February 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 1st 2021
In conclusion, mitophagy pathways play an important role in maintaining physiological homeostasis, are involved in the mechanisms of aging and neurodegenerative disorders, and represent promising targets for the development of potential therapeutic agents aimed at regulating mitochondria quality control in neurons and glial cells. A significant number of molecules that induce or inhibit mitophagy are currently under consideration, which may be useful for testing hypotheses or developing drugs for the treatment of neurodegenerative diseases. The validation of promising drugs in animal and cell models, including neurons and ...
Source: Fight Aging! - October 31, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Analysis of Human Mortality Data at Extreme Old Age from the International Database on Longevity
Very old flies cease to age, at least under the definition of aging as the rise of mortality rate with age. Very old flies have a high mortality rate, but that rate plateaus. There has been some back and forth over the years as to whether such a late life plateau in mortality rates can be observed in humans. Presently the consensus is that it is not apparent. It is, however, challenging to draw any robust conclusions on human mortality past the age of 110, as there are so very few survivors to that late stage of life. All of this is fascinating from a scientific point of view, but something of a sideshow when it comes to t...
Source: Fight Aging! - October 25, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, August 9th 2021
In conclusion, the present study supports that some age-related diseases as well as education are causally related to longevity and highlights several new targets for achieving longevity, including management of venous thromboembolism, appropriate intake of sugar, and control of body fat. Our results warrant further studies to elucidate the underlying mechanisms of these reported causal associations.
Pol III Inhibition Extends Longevity in Short-Lived Species
https://www.fightaging.org/archives/2021/08/pol-iii-inhibition-extends-longevity-in-short-lived-species/
As this paper notes, Pol III is downstream...
Source: Fight Aging! - August 8, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, August 2nd 2021
This study aimed to determine the association between: (i) cognitive decline and bone loss; and (ii) clinically significant cognitive decline on Mini Mental State Examination (MMSE) over the first 5 years and subsequent fracture risk over the following 10 years. A total of 1741 women and 620 men aged ≥65 years from the population-based Canadian Multicentre Osteoporosis Study were followed from 1997 to 2013. Over 95% of participants had normal cognition at baseline. After multivariable adjustment, cognitive decline was associated with bone loss in women but not men. Approximately 13% of participants experienced sign...
Source: Fight Aging! - August 1, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, June 14th 2021
In conclusion, a number of high-income countries, changes in health expectancies over time have not kept pace with the growth in life expectancy. That is, people are living longer but disability and poor health are occupying an increasing proportion of later life. Our findings suggest that countries still need to make significant progress to achieve the WHO's Decade of Healthy Ageing goal of healthier, longer lives for all.
Progress on Understanding Why Human Growth Hormone Receptor Variants are Associated with Greater Longevity
https://www.fightaging.org/archives/2021/06/progress-on-understanding-why-human-gro...
Source: Fight Aging! - June 13, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Today is the day you ’ll have to die
She was listless in bed with agonal breathing — only 63 years old. Before stage 4 colon cancer claimed my mother, she chose to come home to her house … her bedroom, where she’d stare out her window at the dogwood trees that symbolized the blood of Jesus. A once-vibrant Italian Catholic and mother ofRead more …Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Source: Kevin, M.D. - Medical Weblog - June 13, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/debbie-moore-black" rel="tag" > Debbie Moore-Black, RN < /a > < /span > Tags: Conditions Palliative Care Source Type: blogs
There is No One Universal Pro-Longevity Gut Microbiome
Evidence suggests that the gut microbiome is influential on long-term health and late life mortality, to perhaps a similar degree as exercise. The various populations of microbial life found in the gut change with age; microbes producing beneficial metabolites are lost, while microbes that provoke chronic inflammation or other issues increase in number. Experiments in short-lived species have shown that transplanting a youthful microbiome into an older individual results in improved health and extended life span. In principle, similar effects could be achieved by some sort of intensive oral probiotic treatment, but that ha...
Source: Fight Aging! - June 7, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, May 17th 2021
This study is consistent with previous evidence showing that inflammaging, or age-related inflammation, is naturally heightened in the nervous system. Moreover, the authors disproved their hypothesis that anti-inflammatory microglia-specific genes are responsible for the elevated inflammatory response in aged brains since the expression of anti-inflammatory mediators was elevated in middle-aged brains following infection. Thus, the cause for the increase in pro-inflammatory genes remains to be elucidated.
Mixed Results in Animal Studies of Gene Therapy Targeting Axonal Regrowth
https://www.fightaging.org/archiv...
Source: Fight Aging! - May 16, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Whole Genome Sequencing of Supercentenarians in Search of Genetic Contributions to Longevity
In this study, we generated and analyzed the first whole genome sequencing data with high coverage (90X) in a cohort of 81 semi-supercentenarians and supercentenarians [105+/110+] (mean age: 106.6 ± 1.6) recruited across the entire Italian peninsula together with a control cohort of 36 healthy geographically matched individuals (Northern, Central, and Southern Italy) (mean age 68.0 ± 5.9). Data recently published with a second independent cohort of 333 centenarians (100+ years) and 358 geographically matched controls (Northern, Central, and Southern Italy) were used to replicate our results.
We identified five com...
Source: Fight Aging! - May 12, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
5 Insights About The Future Of Health Insurance In The Digital Health Age
The global health insurance market has been experiencing a declining growth rate in recent years; from 9% in 2014-2015 to 6-7% in subsequent years. The 2019 Forbes report that pointed this out also attributes this decline partly to the low adoption of digital solutions in this sector. But those very same solutions can transform the market.
Already with futuristic technologies like clinical grade personal health sensors, at-home genome sequencing kits and artificial intelligence, healthcare is receiving a much-needed overhaul that democratises access to quality care. The health insurance industry could also ride on those sa...
Source: The Medical Futurist - April 22, 2021 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Artificial Intelligence in Medicine Health Insurance Health Sensors & Trackers Healthcare Design Healthcare Policy Medical Education Telemedicine & Smartphones amazon bioprinting data patient gc4 Fitbit genome seque Source Type: blogs
Top 6 Crowdsourcing Examples In Digital Health
During your school years, you might have encountered several instances where your teacher laid out a task or asked a question, and asked you and your classmates to come up with an answer or solution. This “method” somewhat exemplifies crowdsourcing, albeit in analogue form. In essence, the term refers to the act of gathering information or input into a task from a large group of people; or simply, “outsourcing work to the crowd” as the Wired editors who coined the term in 2005 described it.
However, one must not confuse crowdsourcing with crowdfunding. The latter involves raising relatively small amounts of fu...
Source: The Medical Futurist - February 2, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Covid-19 3D Printing Biotechnology Digital Health Research E-Patients Personalized Medicine Telemedicine & Smartphones aids crowdsourcing fda artificial pancreas 3d printed vaccination covid19 immunity passport gaming Foldi Source Type: blogs
