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Covid-19 Reuters Q & A with William Haseltine
I live-tweeted a fascinating and perhaps rather depressing meeting with William Haseltine via a Reuters Newsmaker Broadcast. His talk was upbeat but the message does not offer a positive outlook unless we can collaborate internationally to identify, trace, and isolate and go back to early antivirals to treat people urgently. A vaccine will probably never be found, we must stay on top of this virus when we get communities under control. Moreover, we must recognise that another emergent pathogen could appear any time.
These are essentially my notes from Haseltines’s talk.
Might we ever achieve herd immunity?
There is n...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 20, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs
Covid-19 Reuters Newsmaker Broadcast with William Haseltine
I live-tweeted a fascinating and perhaps rather depressing meeting with William Haseltine via a Reuters Newsmaker Broadcast. His talk was upbeat but the message does not offer a positive outlook unless we can collaborate internationally to identify, trace, and isolate and go back to early antivirals to treat people urgently. A vaccine will probably never be found, we must stay on top of this virus when we get communities under control. Moreover, we must recognise that another emergent pathogen could appear any time.
These are essentially my notes from Haseltines’s talk.
Might we ever achieve herd immunity?
There is n...
Source: David Bradley Sciencebase - Songs, Snaps, Science - May 20, 2020 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs
Fight Aging! Newsletter, April 20th 2020
In conclusion, elevated brain amyloid was associated with family history and APOE ε4 allele but not with multiple other previously reported risk factors for AD. Elevated amyloid was associated with lower test performance results and increased reports of subtle recent declines in daily cognitive function. These results support the hypothesis that elevated amyloid represents an early stage in the Alzheimer's continuum.
Blood Metabolites as a Marker of Frailty
https://www.fightaging.org/archives/2020/04/blood-metabolites-as-a-marker-of-frailty/
Frailty in older people is usually diagnosed in a symptomatic ...
Source: Fight Aging! - April 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Podcast: Is Creativity Enhanced By Mental Illness?
Are people with mental illness more creative? Jackie believes there may be a link between the two, while Gabe thinks it’s just a bunch of hoopla. Get ready — they’ve both done their research and are ready to back their claims. Tune in to hear a lively (and friendly) debate on whether the science is valid, the difference between inspiration and creativity, as well as their own opinions and experiences on mental illness and creativity.
What’s your take? Join us on this Not Crazy podcast to see whose side you’re on, or if you’re somewhere in the middle.
(Transcript Available Below)
SUBSCRIBE & R...
Source: World of Psychology - March 9, 2020 Category: Psychiatry & Psychology Authors: Not Crazy Podcast Tags: Bipolar Creativity Disorders General Mental Health and Wellness Not Crazy Podcast Schizophrenia Source Type: blogs
Fight Aging! Newsletter, February 24th 2020
In conclusion, taller body height at the entry to adulthood, supposed to be a marker of early-life environment, is associated with lower risk of dementia diagnosis later in life. The association persisted when adjusted for educational level and intelligence test scores in young adulthood, suggesting that height is not just acting as an indicator of cognitive reserve.
A Comparison of Biological Age Measurement Approaches
https://www.fightaging.org/archives/2020/02/a-comparison-of-biological-age-measurement-approaches/
Researchers here assess the performance of a range of approaches to measuring biological...
Source: Fight Aging! - February 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Psychology Around the Net: February 1, 2020
This article shares her story of recovery.
Source: World of Psychology - February 1, 2020 Category: Psychiatry & Psychology Authors: Traci Pedersen Tags: Anorexia Anxiety and Panic Disorders Eating Disorders General Medications Mental Health and Wellness Psychology Psychology Around the Net Research Depression gut bacteria Magic Mushrooms postpartum depression psychedelic therap Source Type: blogs
Beyond heart health: Could your statin help prevent liver cancer?
Liver cancer is hard to treat. It’s a top-five cause of cancer-related death worldwide and a growing cause of cancer-related deaths in the United States. Since liver cancer is often found at a late stage, when treatment has limited benefit, there has been increasing interest in prevention. That’s where statin medications might come in.
Liver cancer is usually caused by chronic liver disease, so an important way to prevent liver cancer is to treat the underlying trigger. For example, curing hepatitis C infection — an important cause of chronic liver disease — reduces the risk of liver cancer. However, if the liver d...
Source: Harvard Health Blog - January 27, 2020 Category: Consumer Health News Authors: Irun Bhan, MD Tags: Cancer Drugs and Supplements Health Source Type: blogs
Asinine, Backasswards Colonoscopy Insurance Rules Make Patients Decline Medically Necessary Testing
By HANS DUVEFELT, MD
I’ve had several telephone calls in the last two weeks from a 40-year-old woman with abdominal pain and changed bowel habits. She obviously needs a colonoscopy, which is what I told her when I saw her.
If she needed an MRI to rule out a brain tumor I think she would accept that there would be co-pays or deductibles, because the seriousness of our concern for her symptoms would make her want the testing.
But because in the inscrutable wisdom of the Obama Affordable Care Act, it was decided that screening colonoscopies done on people with no symptoms whatsoever are a freebie, whereas colonosco...
Source: The Health Care Blog - January 27, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Patients Physicians Primary Care Colonoscopy Hans Duvefelt Health insurance Source Type: blogs
Fight Aging! Newsletter, December 23rd 2019
In this study, by adenovirus-mediated delivery and inducible transgenic mouse models, we demonstrate the proliferation of both HCs and SCs by combined Notch1 and Myc activation in in vitro and in vivo inner ear adult mouse models. These proliferating mature SCs and HCs maintain their respective identities. Moreover, when presented with HC induction signals, reprogrammed adult SCs transdifferentiate into HC-like cells both in vitro and in vivo. Finally, our data suggest that regenerated HC-like cells likely possess functional transduction channels and are able to form connections with adult auditory neurons.
Epige...
Source: Fight Aging! - December 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Thou Shalt Not Try to Outsmart Me
By HANS DUVEFELT, MD
Medical researchers and their groupies – early adopters, thoughtleaders, those easily influenced or whatever you want to call them – never seem to learn that when you try to outsmart Mother Nature or Our Heavenly Father, whichever appeals more to your world view, you usually get your hand slapped.
When I was a resident (1981-1984), I got penalized if I didn’t offer postmenopausal women estrogen-progesterone replacement therapy because it seemed obvious that if women with endogenous estrogen didn’t get many strokes or heart attacks and women without estrogen did, all we needed to do was ma...
Source: The Health Care Blog - December 20, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care Hans Duvefelt Source Type: blogs
Epigenetic Mutations Accumulate with Age, with Uncertain Consequences
In this study, we analyzed age-related accumulation of epigenetic mutations from a longitudinal perspective in old Swedish twins, using 994 blood samples collected at up to five time points from 375 individuals in old ages. Apart from being exponentially associated with age, epigenetic mutations were also associated with sex, CD19+ B cell count, genetic background, cancer incidence, and technical factors. We showed once mutations are established, they are stable over time. Furthermore, epigenetic mutations are enriched in important regulatory sites, e.g., promoter regions of genes involved in histone modification processes...
Source: Fight Aging! - December 19, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Public Health To-Do List is Choking Doctors and Jeopardizing Patients ’ Lives
By HANS DUVEFELT, MD
“By the way, Doc, why am I tired, what’s this lump and how do I get rid of my headaches?”
Every patient encounter is a potential deadly disease, disastrous outcome, or even a malpractice suit. As clinicians, we need to have our wits about us as we continually are asked to sort the wheat from the chaff when patients unload their concerns, big and small, on us during our fifteen minute visits.
But something is keeping us from listening to our patients with our full attention, and that something, in my opinion, is not doctor work but nurse work or even tasks for unlicensed staff: Our Publi...
Source: The Health Care Blog - December 17, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Primary Care Hans Duvefelt public health Source Type: blogs
Exclusive with CELLINK Co-Founders Erik Gatenholm and Dr. H éctor Martínez
CELLINK is a 3D bioprinting company based in Gothenburg, Sweden, and was one of the first companies in the world to offer 3D printable bioink, which is used to print human organs and tissues. In just four years of existence, the company has been able...
Source: Medgadget - December 6, 2019 Category: Medical Devices Authors: Alice Ferng Tags: Cardiac Surgery Exclusive Materials Medicine Neurosurgery Source Type: blogs
20 Medical Technology Advances: Medicine in the Future – Part II.
Nanorobots swimming in blood vessels, in silico clinical trials instead of experimenting with drugs on animals and people, remote brain surgeries with the help of 5G networks – the second part of our shortlist on some astonishing ideas and innovations that could give us a glimpse into the future of medicine is ready for you to digest. Here, we’re going beyond the first part with medical tricorders, the CRISPR/Cas-9 gene-editing method, and other futuristic medical technologies to watch for.
11) In silico clinical trials against testing drugs on animals
As technologies transform every aspect of healthcare,...
Source: The Medical Futurist - October 23, 2019 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence E-Patients Future of Medicine Future of Pharma Genomics Health Sensors & Trackers 3d printing AI bioprinting blockchain clinical trials CRISPR digital digital health drug development genetics Innovat Source Type: blogs
