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The Great Bucatini Shortage of 2020 and the FDA ’s History of Telling Italians How to Make Italian Food
Michael F. CannonRachel Handler has a delightfulpiece atNew Yorkmagazine ’s food and restaurant blogGrub Street on how Big Pasta is using government regulation to punish competitors and consumers. The result is that the U.S. Food and Drug Administration, in addition to causing a shortage of COVID-19diagnostic tests andvaccines, is basically causing a nationwide shortage of bucatini.On March 30, at the beginning of a pandemic whose supply shocks were making everything from toilet paper to pasta harder to get, the FDAblocked imports of De Cecco bucatini. The FDA found the iron content of the Italian company’s bu...
Source: Cato-at-liberty - December 30, 2020 Category: American Health Authors: Michael F. Cannon Source Type: blogs
Cancer Survivors Exhibit Greater Risk of New Cancers and Higher Mortality Due to those Cancers
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - December 29, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, December 28th 2020
In conclusion, our study demonstrated that the molecular processes of aging are relatively subtle in their progress, and the aging process of every tissue depends on the tissue's specialized function and environment. Hence, individual gene or process alone cannot be described as the key of aging in the whole organism.
Mouse Age Matters: How Age Affects the Murine Plasma Metabolome
A large part of metabolomics research relies on experiments involving mouse models, which are usually 6 to 20 weeks of age. However, in this age range mice undergo dramatic developmental changes. Even small age differences may l...
Source: Fight Aging! - December 27, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Data for COVID-19 Mortality in Older People in the US
The general consensus on mortality due to COVID-19 is that it falls most heavily on people who are more impacted by aging: poor immune function when it comes to defense against pathogens; high levels of chronic inflammation that create a greater susceptibility to the way in which SARS-CoV-2 kills people; existing chronic disease; and a mortality rate that is already high even setting aside the pandemic. When younger people die due to the virus, in much smaller numbers, it is where they share these characteristics of inflammation, deficient immune systems, and chronic disease. This level of morbidity is unusual in younger i...
Source: Fight Aging! - December 23, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
An Enlightening Protein
A fruit fly expressing GFP. Credit: Jay Hirsh, University of Virginia.
During the holiday season, twinkling lights are a common sight. But no matter what time of the year, you can see colorful glows in many biology labs. Scientists have enabled many organisms to light up in the dark—from cells to fruit flies and Mexican salamanders. These glowing organisms help researchers better understand basic cell processes because their DNA has been edited to express molecules such as green fluorescent protein.
Illuminating Cell Processes
A zebrafish fin with GFP glowing (green dots) where gene sox9b is expressed. This...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 23, 2020 Category: Research Authors: Chrissa Chverchko Tags: Genes Tools and Techniques Cool Tools/Techniques DNA Proteins Source Type: blogs
Shingles: What triggers this painful, burning rash?
If you’re like 95% of American adults, you had chickenpox as a kid. Before the United States started its widespread vaccination program in 1995, there were roughly four million cases of chickenpox every year. So, most people suffered through an infection with this highly contagious virus and its itchy, whole-body rash.
But unlike many childhood viruses, the varicella-zoster virus that causes chickenpox doesn’t clear from the body when the illness ends. Instead it hangs around, taking up residence and lying dormant in the nerves, sometimes for decades, with the immune system holding it in check. In some people, it lives...
Source: Harvard Health Blog - December 14, 2020 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Health Healthy Aging Skin and Hair Care Vaccines Source Type: blogs
Fight Aging! Newsletter, December 14th 2020
In conclusion, aging alters the cerebral vasculature to impair mitochondrial function and mitophagy and increase IL-6 levels. These alterations may impair BBB integrity and potentially reduce cerebrovascular health with aging.
Senescent Cells Fail to Maintain Proteostasis
https://www.fightaging.org/archives/2020/12/senescent-cells-fail-to-maintain-proteostasis/
Given the newfound consensus in the research community regarding the importance of senescent cells to degenerative aging, it isn't surprising to see a great deal more fundamental research into the biochemistry of cellular senescence now taking pla...
Source: Fight Aging! - December 13, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Analysis of Human Inheritance of Longevity is not as Straightforward as One Might Think
Here, researchers note some of the challenges inherent in trying to analyze data on human inheritance of longevity; it isn't as easy as it sounds. Considerable effort has gone into analysis of long-lived families to try to identify genetic variants that might explain why some lineages exhibit greater longevity than others. Nonetheless, so far only a small number of gene variants have been robustly demonstrated to influence human longevity. This poor yield is not for lack of searching, but because it seems likely that individual genetic contributions to longevity are both very small and very specific to environmental circum...
Source: Fight Aging! - December 11, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Top 10 Online Medical Resources For The Patients Of The Future
There are over 1 billion health-related searches on Google every single day, according to a report. This was about 7% of all searches on the platform before, and no one will be surprised when the 2020 data massively surpasses this number. After all, the internet is likely the first source to turn to with your health-related questions.
But which hits are relevant, and which lead to straightforward la la land – even with the best intentions and the best A.I. toolset, the search giant can’t exclude the latter from among the results. And yet, doing so is especially important in the case of medicine and healthcare, s...
Source: The Medical Futurist - December 10, 2020 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research E-Patients Medical Education Medicine social media Webicina webmd gc2 online resources pharmaceutics Topol Mayo Clinic ePatients Medscape Eric Topol Smart Patients Medline Plus National Library of Source Type: blogs
Podcast: Celebrating a COVID Christmas
We’ve made it to the end of 2020! From polarizing politics to raging fires to COVID-19, it’s been a real doozy. And now the holidays… Do we celebrate with loved ones and risk COVID or take a pass? What are the risks?
In today’s show, our guest Dr. John Grohol, founder of Psych Central, explains how this isn’t going to be our regular holiday season and that’s okay: We can easily make lemonade out of lemons.
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Guest information for ‘Dr. John Grohol- COVID Christmas’ Podcast Episode
John M. Grohol, Psy.D. is a pioneer in online mental health and psychology. Recognizing the edu...
Source: World of Psychology - December 3, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: General Holiday Coping Interview Podcast The Psych Central Show Source Type: blogs
Fight Aging! Newsletter, November 23rd 2020
In conclusion, the study indicates that HBOT may induce significant senolytic effects that include significantly increasing telomere length and clearance of senescent cells in the aging populations.
Data on the Prevalence of Liver Fibrosis in Middle Age
https://www.fightaging.org/archives/2020/11/data-on-the-prevalence-of-liver-fibrosis-in-middle-age/
Fibrosis is a consequence of age-related disarray in tissue maintenance processes, leading to the deposition of scar-like collagen that disrupts tissue structure and function. It is an ultimately fatal issue for which there are only poor treatment options a...
Source: Fight Aging! - November 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Is the Republican Brand Dying?
There’s a lot of talk about how supporting Trump may take down the Republican party. Perhaps that remains to be seen, but I wanted to do a little test within my own mind to see what I associate to each of these terms today, at least from a branding perspective. I was curious how the past four years may have influenced what I associate with the word Republican.
Before Trump came onto the political scene, I tended to regard Republicans as mostly harmless but also patriotic, religious, and moralistic. I had plenty of friends who identified as Republican, and I found it easy to relate to them. Our interactions were pl...
Source: Steve Pavlina's Personal Development Blog - November 10, 2020 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Values Source Type: blogs
What Will Shape Joe Biden ’s Health Care Agenda?
I’m thrilled to have health futurist Jeff Goldsmith back on THCB, and given Biden was only confirmed as President-elect this morning, his article on what to expect is extremely timely!–Matthew Holt
By JEFF GOLDSMITH
The Trump administration’s health care journey began with a trillion dollar near miss–the failed Repeal and Replacement of ObamaCare- and ended with a full-on train wreck, the catastrophically mismanaged COVID epidemic that will have claimed 300,000 lives by the time he leaves office. After four years of posturing and lethal incompetence, it will be a relief to see caring and pr...
Source: The Health Care Blog - November 7, 2020 Category: Consumer Health News Authors: matthew holt Tags: Health Policy OP-ED Politics THCB ACA Biden Jeff Goldsmith States Unions Source Type: blogs
They ' ve Gone Coup-Coup
Science confirms consistent neurophysiological and psychological differences between conservatives and liberals. How they react to threats. Their reliance on the observable and their response to presented facts. Evolutionary biologists have theories, but it ’s intuitive that, in addition to rationalists, primitive societies benefitted from people who don’t need no damn proof to react to perceived threats. Noises. Shadows. Gut feelings. It could avoid becoming a meal.Who knows why such brains remain in circulation? Individuals are safer now. More often than not, there ’s time to think, evaluate. Threats from saber-too...
Source: Surgeonsblog - November 5, 2020 Category: Surgery Authors: Sid Schwab Source Type: blogs
A Cure at Any Cost? Time to Shine a Light on Drug Pricing
By CECI CONNOLLY and BOBBY CLARK
We are all are anxiously awaiting the approval and delivery of a cure to the novel coronavirus – or better yet, a vaccine.
Amid the race to develop a safe and effective vaccine, some may be inclined to give drug companies a pass on their well-established bad behavior related to pricing and market competition.
But that would be an awfully expensive mistake.
As the COVID-19 pandemic claims more lives and families’ livelihood, policymakers and the public must press drug makers for more information on the products they are developing. The country must be protected agains...
Source: The Health Care Blog - November 2, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy bobby clark Ceci Connolly COVID-19 Drug Pricing Pharma Source Type: blogs
