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Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Bridging the Representation Gap in Biomedical Research
“We hope that students come out of our program feeling like they’re part of a community. Many of us feel inadequate or struggle in some way during graduate school—it can be a challenging time. I want to build a community that our students can always come back to for support,” says Elana Ehrlich, Ph.D., the co-director of the Bridges to the Doctorate Research Training Program (B2D) at Towson University in Towson, Maryland, alongside Michelle Snyder, Ph.D..
The Towson B2D is one of several NIGMS-supported B2Ds, which are dedicated to developing a diverse pool of well-trained biomedical scientists who will transiti...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 30, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Training Source Type: blogs
Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan.
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Trials of Xenotransplantation of Pig Organs into Humans Continue
https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants in...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
THCB 20th Birthday Classic: As I’ve always suspected, Health Care = Communism + Frappuccinos
By MATTHEW HOLT
Our 20th birthday continues with a few classics coming out. Back in 2005 I was really cutting a lyrical rug, and would never miss a chance to get that Cambridge training in Marxism into use. This essay about whether health care should be a public or private good has always been one of my favorites, even if I’m not sure Starbucks is still making Frappuccinos. And 18 years later the basic point of this essay remains true, even if many of you will not have a clue who Vioxx or Haliburton were or why they mattered back then!
Those of you who think I’m an unreconstructed commie will correctly suspec...
Source: The Health Care Blog - August 15, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Matthew Holt Communism Frappuccinos Source Type: blogs
Visually Guided Uterine Biopsies in Physician ’s Office: Interview with Allison London Brown, CEO of LUMINELLE
LUMINELLE, a medtech company based in North Carolina, has developed a suite of endoscopic tools that allow clinicians to perform visually guided gynecological procedures right from their office. At present, the majority of uterine biopsies taken to i...
Source: Medgadget - August 4, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Ob/Gyn Source Type: blogs
Fight Aging! Newsletter, July 31st 2023
In conclusion, an SBP level below 130 mmHg was found to be associated with longevity among older women. The longer SBP was controlled at a level between 110 and 130 mmHg, the higher the survival probability to age 90. Preventing age-related rises in SBP and increasing the time with controlled BP levels constitute important measures for achieving longevity.
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Source: Fight Aging! - July 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Cell Replication Changes the Epigenome in Ways that Connect to Cancer
Researchers here demonstrate that one can create a signature of replication-based epigenetic change in cells, and that this signature is stronger in old tissues and cancerous tissues. This leads to a view in which increased replication stress on cells in a tissue, meaning a tissue that is made up of cells that have divided more times on average, have shorter telomeres, and are closer to the Hayflick limit, creates an environment that is epigenetically predisposed towards cancer. Looking at this another way, aging is characterized by reduced stem cell function, meaning a lower pace of creation of daughter somatic cells to r...
Source: Fight Aging! - July 27, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Closing the Gap: Why Healthcare Needs More Gender Diversity in Leadership
The following is a guest article by Dr. Erica Barnell, MD, PhD, Co-Founder and Chief Science Officer at Geneoscopy
Women comprise 70% of the healthcare workforce and 59% of medical, biomedical, and health sciences graduates, yet are the minority at leadership levels — holding only 25% of senior executive roles. As a result, the lack of women in significant decision-making positions is evident.
According to U.S. Census estimates, no single ethnic or racial group will represent a majority of the U.S. population by 2055. The potential for more positive patient care experiences, greater innovation, and improved organizatio...
Source: EMR and HIPAA - July 26, 2023 Category: Information Technology Authors: Guest Author Tags: C-Suite Leadership Clinical Health IT Company Healthcare IT Dr. Erica Barnell Dr. Erica Barnell MD PhD Gender Bias Gender Diversity in Healthcare Leadership Geneoscopy Women in Healthcare Women in Leadership Women in STEM Women's H Source Type: blogs
Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.
Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease
https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/
With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Major evidence review supports an “exercise prescription” for most adults to boost mental health and well-being
Conclusion and relevance: Physical activity is highly beneficial for improving symptoms of depression, anxiety and distress across a wide range of adult populations, including the general population, people with diagnosed mental health disorders and people with chronic disease. Physical activity should be a mainstay approach in the management of depression, anxiety and psychological distress.
The Study in Context:
Can you grow your hippocampus? Yes. Here’s how, and why it matters
Three ways to protect your mental health during –and after– COVID-19
Solving the Brain Fitness Puzzle Is the Key to Self-Empowered Aging
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Source: SharpBrains - July 6, 2023 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning Peak Performance anxiety depression exercise exercise prescription gym improve mental health lift weights medication mental-health-treatment physical-health therapy yoga class Source Type: blogs
How Automation Can Help Ease Healthcare Worker Burnout
The following is a guest article by Anna Twomey, Senior Director, Healthcare Providers – Americas at SS&C Blue Prism
With rising staffing shortages and burnout among healthcare workers, digital transformation will be key to overcoming these challenges and protecting patient care. It’s estimated that the U.S. could see a shortage of up to 124,000 physicians by 2033 and will need to hire at least 200,000 nurses per year to meet increased demand and to replace retiring nurses. The healthcare worker burnout crisis in this country began before the COVID-19 pandemic, but the public health emergency m...
Source: EMR and HIPAA - June 28, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Anna Twomey BPM Business Process Management Digital Transformation EHR Healthcare Automation Healthcare Burnout IA Intelligent Automa Source Type: blogs
Career Conversations: Q & A With Physiologist Elimelda Moige Ongeri
Credit: Courtesy of Dr. Elimelda Moige Ongeri.
A career path in science is rarely clear cut and linear, which Elimelda Moige Ongeri, Ph.D., can attest adds to its excitement. She went from working in animal reproductive biology to studying proteins involved in inflammation and tissue injury. Dr. Ongeri is also currently dean of the Hairston College of Health and Human Sciences and professor of physiology at North Carolina Agricultural and Technical State University (NC A&T) in Greensboro. In this interview, she shares details of her career, including a change in research focus to human physiology; her goals for the f...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 14, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Profiles Proteins Source Type: blogs
Doubt, Deferral, and Destiny
Five years ago, if you told me that I would be an entering MD/PhD student, I’d be elated, but if you had told me two years ago — I’d laugh and call you a liar. It’s strange that along my journey to medical school and physician-scientist training, there was such a low point, but one that many medical students can relate to: impostor syndrome during the application cycle.
I had been working toward this point throughout college, and before I started writing my applications, I felt reasonably confident in my goal to become a physician-scientist studying cancer biology. Yet the writing process brought my doubts, ...
Source: Academic Medicine Blog - May 25, 2023 Category: Universities & Medical Training Authors: Laura Siegel Tags: imposter syndrome Source Type: blogs
ChatGPT In Healthcare: What Science Says
This study demonstrates that ChatGPT, a large language model, can assist in radiologic decision-making at the point of care, achieving moderate to high accuracy in determining appropriate imaging steps for breast cancer screening and breast pain evaluation, although limitations of the model, such as misalignment and “hallucinations”, must be considered when designing clinically-oriented prompts for use with large language models.Analysis of large-language model versus human performance for genetics questionsMedrxivThe use of language models like ChatGPT in clinical genetics has the potential to provide rapid an...
Source: The Medical Futurist - May 25, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine ChatGPT digital health large language models ChatGPT in healthcare AI in healthcare AI in medicine Source Type: blogs
