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Bridging the Representation Gap in Biomedical Research
“We hope that students come out of our program feeling like they’re part of a community. Many of us feel inadequate or struggle in some way during graduate school—it can be a challenging time. I want to build a community that our students can always come back to for support,” says Elana Ehrlich, Ph.D., the co-director of the Bridges to the Doctorate Research Training Program (B2D) at Towson University in Towson, Maryland, alongside Michelle Snyder, Ph.D.. The Towson B2D is one of several NIGMS-supported B2Ds, which are dedicated to developing a diverse pool of well-trained biomedical scientists who will transiti...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 30, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Training Source Type: blogs

Ming Lei Departs Division for Research Capacity Building
It’s with mixed emotions that I share that Ming Lei left our Division for Research Capacity Building (DRCB) earlier this month to become senior associate vice president for research and graduate education at West Virginia University (WVU) Health Sciences. Ming also joined the faculty in WVU’s School of Medicine as vice dean for research and a professor in the department of microbiology, immunology, and cell biology. Ming has been part of the NIH community since 2008, serving in key positions at the National Cancer Institute before joining NIGMS in 2018. During his tenure in DRCB, Ming led numerous initiatives to...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - August 24, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages NIGMS Staff News Source Type: blogs

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Top 10 Health Chatbots
This study from March 2023 reports how an app developed to help patients’ bowel preparation can increase compliance and thus, the number of successful colonoscopies. In some cases, health chatbots are also able to connect patients with clinicians for diagnosis or treatment, but that is one step further down the line. The general idea is that in the future, these talking or texting smart algorithms might become the first contact point for primary care. Patients will not get in touch with physicians or nurses or any medical professional with every one of their health questions but will turn to chatbots first. If th...
Source: The Medical Futurist - August 1, 2023 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine Healthcare Design health chatbot Innovation List medical Personalized medicine AI technology digital health chatbots Source Type: blogs

Health misinformation ’ s deadly impact
Turning into vegetarians can cure COVID-19, birth control pills cause abortions, or eating ginger is 10,000 times more effective than chemotherapy at curing cancer were some casually trending health misinformation in the past year. But what is health misinformation, and why is it a serious public health concern? Health misinformation refers to health-related information that Read more… Health misinformation’s deadly impact originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - July 29, 2023 Category: General Medicine Authors: Tags: Policy Mainstream media Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, July 10th 2023
In conclusion, the examination of the GBA can aid in understanding the etiology and development of NDs, which may benefit the improvement of clinical treatments for these disorders and ND interventions. This review indicates existing knowledge about the involvement of microbiota present in the gut in NDs and potential treatment options. The Aging of the Enteric Nervous System https://www.fightaging.org/archives/2023/07/the-aging-of-the-enteric-nervous-system/ The enteric nervous system is the nervous system of the intestines, and likely an important part of the relationship between the gut microbiome a...
Source: Fight Aging! - July 9, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Major evidence review supports an “exercise prescription” for most adults to boost mental health and well-being
Conclusion and relevance: Physical activity is highly beneficial for improving symptoms of depression, anxiety and distress across a wide range of adult populations, including the general population, people with diagnosed mental health disorders and people with chronic disease. Physical activity should be a mainstay approach in the management of depression, anxiety and psychological distress. The Study in Context: Can you grow your hippocampus? Yes. Here’s how, and why it matters Three ways to protect your mental health during –and after– COVID-19 Solving the Brain Fitness Puzzle Is the Key to Self-Empowered Aging ...
Source: SharpBrains - July 6, 2023 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning Peak Performance anxiety depression exercise exercise prescription gym improve mental health lift weights medication mental-health-treatment physical-health therapy yoga class Source Type: blogs

Age-Associated B Cells Correlate with Impaired Immune Response
Age-associated B cells are one of a number of dysfunctional or maladaptive immune cell subpopulations that appear in increasing numbers in later late, and which likely impair the many functions of the immune system by their presence. Clearing all B cells rather than trying to selectively clear age-associated B cells is a viable proposition, as the B cell population regenerates quite rapidly following clearance, and the new cells lack the age-associated B cell phenotype. This has been demonstrated in animal models, but has yet to make it to the clinic as a treatment to improve the aged immune system. Age-associated...
Source: Fight Aging! - July 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models. The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Concept of Immune Resilience and Its Relevance to Degenerative Aging
The aging of the immune system is widely considered a progressive loss of functional capacity, such as the ability to effectively destroy pathogens and errant cells (known as immunosenescence), coupled to rising levels of unresolved, chronic inflammation (known as inflammaging). In today's open access paper, the authors are more interested in how well the immune system brings itself back to an equilibrium state following the disruptions of an inflammatory response. They call this capacity for restoration "immune resilience". In this framework, aging brings a loss of the ability to restore normality to the immune system fol...
Source: Fight Aging! - June 23, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Better Health Care Tests, Faster
This article looks at some specific problems and solutions. Speeding up Test Development We’ve seen with COVID-19 how quickly a virus can evolve and how hard it is to design both tests and vaccinations that accommodate different variants. Virax Biolabs uses data from the World Health Organization and others to develop tests quickly. For instance, new viral variants tend to spread in the southern hemisphere before hitting the northern hemisphere in our Winter, so Virax can check existing data to prepare better tests for the North. The company is developing a T-cell diagnostics and profiling platform called Virax Immu...
Source: EMR and HIPAA - June 13, 2023 Category: Information Technology Authors: Andy Oram Tags: Health IT Company Healthcare IT Hospital - Health System Interoperability CLIA COVID-19 Hydreight Immunexpress ixlayer Laboratories Labs Rolland Carlson Sepsis Sepsis Lab Tests Septicyte Shane Madden testing Tomasz George Source Type: blogs

MA for Tomorrow: Moving Beyond the Status Quo to Advance Concrete Policy Changes for the Future of Medicare Advantage
BY CECI CONNOLLY AND MICHAEL BAGEL Medicare Advantage (MA) has passed the tipping point, delivering coverage and care to more than half of the senior population in the US. The Congressional Budget Office projects more than 60 percent of people 65 years and older will be in the program by 2030. As enrollment soars and interest in value-based health care grows, it is imperative policymakers modernize the program that is expected to cost $7.5 trillion over the next decade. Rather than taking the standard Washington posture of declaring victory or defending the status quo, our provider-aligned, nonprofit member pla...
Source: The Health Care Blog - June 12, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Ceci Connolly MA for Tomorrow Medicare Advantage Michael Bagel Source Type: blogs