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Fight Aging! Newsletter, December 4th 2017
In this study, we integrated atomic force microscopy (AFM) and molecular approaches to determine whether increased stiffness of aortic VSMCs in hypertensive rats is ROCK-dependent, and whether the anti-hypertensive effect of ROCK inhibitors contributes to the reduction of aortic stiffness via changing VSMC mechanical properties.
Despite a widely held belief that aortic stiffening is associated with changes in extracellular matrix proteins and endothelial dysfunction, our recent studies demonstrated that intrinsic stiffening of aortic VSMCs, independent of VSMC proliferation and migration, is an important contributo...
Source: Fight Aging! - December 3, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
An Update on Leukocyte Transfer Cancer Therapy Development
LIFT, or GIFT, is an approach to cancer therapy that involves transplantation of suitably aggressive leukocyte or granulocyte immune cells. While cancers have numerous ways to suppress the native immune response, they can be vulnerable to foreign immune cells from a donor. Not all donors, but perhaps a few in a hundred on average will have immune cells capable of rapidly destroying a patient's cancer. In principle this approach should be able to target many different types of cancer, which is exactly what we need to see from the research community: more of broadly applicable approaches, and less of very specific cancer the...
Source: Fight Aging! - November 27, 2017 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
MKSAP: 35-year-old man with upper abdominal discomfort
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 35-year-old man is evaluated for a 2-month history of upper abdominal discomfort after eating. He has recently returned from working in a rural area of a developing country. He takes no medications. There is no family history of esophageal or gastric cancer.
On physical examination, vital signs are normal. BMI is 40. Centripetal obesity is noted, but abdominal examination findings are otherwise normal.
Laboratory studies reveal a hemoglobin level of 15 g/dL (150 g/L).
Which of the following is the most appropr...
Source: Kevin, M.D. - Medical Weblog - November 4, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Gastroenterology Infectious Disease Source Type: blogs
Technologies Change Health Insurance: The Most Innovative Ventures
The accumulation of medical data enables health insurance companies to move from the 100-year-old concept of reactive care to preventive medicine. The future points to simple, fast and highly personalized insurance plans based on information from the healthcare system and data from health sensors, wearables, and trackers. Here is the changing health insurance scene and its most innovative solutions!
Health insurance systems are unsustainable partly due to costly chronic diseases
According to OECD predictions, exceeding budgets on health spending remains an issue for OECD countries. Maintaining today’s healthcare systems...
Source: The Medical Futurist - October 31, 2017 Category: Information Technology Authors: nora Tags: Future of Medicine Healthcare Design big data chronic illness digital digital health gc3 health data health insurance healthcare data technology trackers wearables Source Type: blogs
PHE Cancer Board plan: 2017 to 2021
Public Health England (PHE) - This plan outlines the approach to co-ordinating PHE's cancer work for the next five years. It is aligned with the Five year forward view and the Independent Cancer Taskforce report and highlights how we will work in partnership with others to achieve the recommendations and enhance PHE’s role in the fight against cancer.PlanPHE publications
Source: Health Management Specialist Library - October 13, 2017 Category: UK Health Authors: The King ' s Fund Information & Knowledge Service Tags: Quality of care and clinical outcomes Source Type: blogs
I ’ m 35 Years Old And I ’ m Realizing My Life May Be About to End. And I ’ m Panicking, Just a Little.
By SCOTT RIDDLE
It’s been a while since I put a piece of writing in the public domain, but suddenly I have a lot to get off my chest, well my colon actually.
Just three weeks ago life was good. Correction. It was awesome. The newest edition to our family had arrived on Christmas Eve, joining his two sisters aged 5 and 3. A month later we were on a plane home to Sydney, having spent four great years working for Google in California. My beautiful wife had been working at a startup on NASA’s Moffett campus and was worried about finding something equally interesting in Australia, but she managed to land a very similar gig...
Source: The Health Care Blog - October 4, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Cancer Colon Cancer Scott Riddle Source Type: blogs
My Guide To The Future of Medicine: 22 Trends Shaping Healthcare
Digital technologies have completely transformed our lives in the last couple of years and started to entirely reshape the landscape of healthcare. Yet, this is only the beginning. Huge waves of changes are on their way. Thus, it is of utmost importance to familiarize with the latest technologies and trends in medicine to be able to prepare for the future in time. And while doing so, not to lose the quintessence of practicing medicine, the human touch. That’s the synopsis of the newest edition of my book, The Guide to the Future of Medicine.
Today’s healthcare innovations sound like yesterday’s science fiction
Surge...
Source: The Medical Futurist - September 21, 2017 Category: Information Technology Authors: nora Tags: Bioethics Biotechnology Future of Medicine artificial intelligence digital digital health GC1 genetics Healthcare Innovation social media wearables Source Type: blogs
Policy Primers: Prescription Drug Pricing And Consumer Costs
Health Affairs has released the final set in a series of peer-reviewed health policy briefs on key issues currently shaping the prescription drug market. This third set of briefs looks at key factors that explain the many issues determining consumer out-of-pocket spending and contribute to the confusion between list prices and net prices. They are:
The 340B Drug Discount Program
The 340B drug discount program mandates the sale of outpatient prescription drugs to safety-net providers at reduced rates.
Patient Financial Support
Manufacturer-sponsored financial support helps patients afford medicines but may thwart payers’ ...
Source: Health Affairs Blog - September 14, 2017 Category: Health Management Authors: Health Affairs Tags: Elsewhere@ Health Affairs policy primers Source Type: blogs
Think Different about Patient Engagement: Aetna, Apple, and a Vision of Digital Health ’s Future, Part 2
By LYGEIA RICCARDI
This is the second post in a series on digital health inspired by Aetna and Apple, whose developing partnership is poised to impact millions of Americans. Part 1 is Mystery Mission in LA.
Getting to Patient Engagement
“Patient engagement” is a popular phrase in healthcare these days, but how do you actually get people to take a greater role vis a vis their own health and healthcare? As the first Director of Consumer eHealth at ONC in the US federal government, I spent several years making the case for strengthening patient engagement with technology, and trying to figure out how to make it happen a...
Source: The Health Care Blog - August 28, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs
MKSAP: 58-year-old man with cancer of the ascending colon
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 58-year-old man undergoes follow-up evaluation for cancer of the ascending colon diagnosed 3 weeks ago. Colonoscopy at that time revealed a fungating mass in the ascending colon. Biopsy revealed adenocarcinoma, and additional studies showed no evidence of metastatic disease. Right hemicolectomy was performed. The pathology report showed a 4-cm primary adenocarcinoma with clear margins at resection, full-thickness penetration through the colonic wall into pericolonic fat, and 4/21 lymph nodes involved (stage II...
Source: Kevin, M.D. - Medical Weblog - August 26, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Gastroenterology Oncology/Hematology Source Type: blogs
Making Smoking Cessation Work For People With Mental Illnesses And Other Vulnerable Populations
The prevalence of cigarette smoking among adults is now at a modern low of 15 percent, and youth rates are also down for high school seniors, with only 3.4 percent smoking daily. Yet this is not a time to become complacent and move on to other public health problems. As many as 40 million people still smoke, and half of them will die prematurely as a result. Furthermore, smoking rates remain high among the most vulnerable populations, such as people with mental illnesses or substance use disorders, necessitating policies and strategies targeted specifically at them, as well as support for tobacco control at the federal, st...
Source: Health Affairs Blog - August 23, 2017 Category: Health Management Authors: Steven Schroeder Tags: Featured Health Equity Population Health Public Health Behavioral Health Mental Illness smoking cessation Substance Use Disorders vulnerable populations Source Type: blogs
Effective forms management improves healthcare data quality
When was the last time you thought about the forms strategy in your organization? Most of us think about forms as a clerical activity but proper management of patient forms drives important clinical and business initiatives such as patient satisfaction, patient quality scores, and care coordination analytics. With so much emphasis in healthcare put on collecting quality data, information exchange, analytics, patient generated health data, and more, it’s surprising how little attention is put on the way this important information is collected.
Forms remain an important method of collecting structured information in health...
Source: The Healthcare IT Guy - August 23, 2017 Category: Information Technology Authors: Shahid N. Shah Tags: Uncategorized document workflow technology Electronic health records forms management tools forms solutions forms technology Source Type: blogs
Fight Aging! Newsletter, August 14th 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - August 13, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
MKSAP: 54-year-old man with dysphagia
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 54-year-old man is evaluated for a 4-month history of intermittent, nonprogressive solid-food dysphagia. He has a long-standing history of heartburn that has been well controlled with once-daily proton-pump inhibitor (PPI) therapy for the past 5 years. Results of a screening colonoscopy 4 years ago were normal. There is no family history of colorectal cancer.
Physical examination findings are unremarkable.
Upper endoscopy reveals a 3-cm hiatal hernia, an esophageal (Schatzki) ring, and approximately six polyps...
Source: Kevin, M.D. - Medical Weblog - August 12, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions GI Medications Source Type: blogs
Ultrasound to Improve Effectiveness of Cancer Drugs: Interview with Focused Ultrasound Foundation ’s Jessica Foley, PhD
Most people think of ultrasound as an imaging modality. Yet, there are many other clinical uses for the high frequency soundwaves. Focused ultrasound waves can promote the opening of the blood-brain barrier, and they can be used to ablate fibroids, a...
Source: Medgadget - August 10, 2017 Category: Medical Devices Authors: Editors Tags: Medicine News Source Type: blogs
