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Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Beyond the Scale: How organizations should evaluate the success of obesity management solutions
Conclusion
Organizations have much to consider when evaluating obesity solutions for their population. It’s easy to be swayed by simple metrics that seem indisputable. But, in the end, outcomes like 5% weight loss and reductions in HbA1c for the majority of an eligible population are what counts. Sustainable outcomes rely on real behavior change, a careful step-therapy approach to medication, and personalized care when it comes to social determinants of health.
Caitlyn Edwards, PhD, RDN, is a Senior Clinical Research Specialist at Vida Health
Source: The Health Care Blog - September 8, 2023 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice Caitlyn Edwards GLP-1 Obesity SDoH vida health Source Type: blogs
A Discussion of Current Approaches Under Development for the Treatment of Aging
This open access paper tours a number of the present approaches under development to the treatment of aging as a medical condition, dwelling the most on therapies targeting senescent cells, either for destruction or to suppress the harmful senescence-associated secretory phenotype. We live in an exciting time of great potential, an age of accelerating progress in the capabilities of medical biotechnology, though it remains the case that too few people realize just how close we are to the widespread use of the first practical rejuvenation therapies.
Aging poses one of the greatest challenges for modern medicine, as...
Source: Fight Aging! - September 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Preventative Health and Longevity Company, Viome Life Sciences, Closes $86.5M Oversubscribed Series C Funding Round
Additional Financing Supports the Further Development of its Suite of Advanced Personalized Health Tests and Expansion into Key Nationwide Retailers such as CVS
Viome Life Sciences, a longevity company committed to translating scientific advancements into practical and individualized health solutions, today announced the successful closure of its $86.5 million oversubscribed Series C funding round. Lead investors include Khosla Ventures and Bold Capital with participation from other existing ones as well as new ones. The raise brings Viome’s total to $175 million and will be used to support research and development and r...
Source: EMR and HIPAA - August 31, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Bold Capital CVS Gut Intelligence Test Health IT Funding Health IT Fundings Health IT Investment Khosla Ventures Naveen Jain Robbie Schwietzer Viome Viome Life Sciences Source Type: blogs
Bridging the Representation Gap in Biomedical Research
“We hope that students come out of our program feeling like they’re part of a community. Many of us feel inadequate or struggle in some way during graduate school—it can be a challenging time. I want to build a community that our students can always come back to for support,” says Elana Ehrlich, Ph.D., the co-director of the Bridges to the Doctorate Research Training Program (B2D) at Towson University in Towson, Maryland, alongside Michelle Snyder, Ph.D..
The Towson B2D is one of several NIGMS-supported B2Ds, which are dedicated to developing a diverse pool of well-trained biomedical scientists who will transiti...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 30, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Training Source Type: blogs
Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan.
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Trials of Xenotransplantation of Pig Organs into Humans Continue
https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants in...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Dietary Habit That Prevents Prostate Cancer And Speeds Recovery
The nutrients that may halt one of the deadliest cancers in men and speed up their recovery after radiotherapy.
Source: PsyBlog | Psychology Blog - August 21, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Cancer Source Type: blogs
Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, August 7th 2023
In conclusion, here, we demonstrate a novel mechanism for ESC-EVs to protect cells from senescence. However, whether ESC-EVs rejuvenate aged mice via miR-15b-5p and miR-290a-5p remains unknown. Next, we plan to use miR-15b-5p and miR-290a-5p antagonists while treating aged mice with ESC-EVs to further investigate the mechanism by which ESC-EVs resist aging in vivo.
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Fatty Acid Metabolism as a Commonality in Different Approaches to Slowing Aging
https://www.fightaging.org/archives/2023/08/fatty-acid-metabolism-as-a-commonality-in-different-approaches-to-slowing-aging/
It seems...
Source: Fight Aging! - August 6, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Strategy and Tactics: Two Essential Keys to Success
I recently read Outlive by Peter Attia. It’s a book about longevity that I found insightful. It contains many lessons about different aspects of health.
However, what I’d like to share with you here isn’t the health lessons from the book. Instead, it’s a quote by Sun Tzu that I found there:
Strategy without tactics is the slowest route to victory. Tactics without strategy is the noise before defeat.
Interesting quote, isn’t it? Strategy without tactics might lead you to victory, but it’s the slowest route to get there. You will waste a lot of resources along the way. On the other hand, tactics without ...
Source: Life Optimizer - August 5, 2023 Category: Consumer Health News Authors: Donald Latumahina Tags: Productivity Thinking Source Type: blogs
The Top 10 Health Chatbots
This study from March 2023 reports how an app developed to help patients’ bowel preparation can increase compliance and thus, the number of successful colonoscopies.
In some cases, health chatbots are also able to connect patients with clinicians for diagnosis or treatment, but that is one step further down the line. The general idea is that in the future, these talking or texting smart algorithms might become the first contact point for primary care. Patients will not get in touch with physicians or nurses or any medical professional with every one of their health questions but will turn to chatbots first. If th...
Source: The Medical Futurist - August 1, 2023 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Medicine Healthcare Design health chatbot Innovation List medical Personalized medicine AI technology digital health chatbots Source Type: blogs
