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Fall Activities for NIGMS Trainees
Welcome to the NIGMS Feedback Loop! As a current NIGMS trainee, you’re automatically subscribed to our blog so that we can provide you with information about upcoming meetings and events, opportunities to provide your input, program news, and more.
As the school yearbegins, we’d like to start by sharing upcoming NIGMS-supported events you can participate in.
We’re holding our annual Judith H. Greenberg Early Career Investigator Lecture virtually and on the NIH campus in Bethesda, Maryland, on September 27. The speaker is Akhila Rajan, Ph.D., from the Fred Hutchinson Cancer Center, and she’ll describe her ...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - September 18, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: NIGMS Trainee Community Source Type: blogs
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Discussion of Current Approaches Under Development for the Treatment of Aging
This open access paper tours a number of the present approaches under development to the treatment of aging as a medical condition, dwelling the most on therapies targeting senescent cells, either for destruction or to suppress the harmful senescence-associated secretory phenotype. We live in an exciting time of great potential, an age of accelerating progress in the capabilities of medical biotechnology, though it remains the case that too few people realize just how close we are to the widespread use of the first practical rejuvenation therapies.
Aging poses one of the greatest challenges for modern medicine, as...
Source: Fight Aging! - September 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Eggs And High Blood Pressure: Decoding The Dietary Dilemma
Conclusion
In navigating the winding road of managing high blood pressure, several key points emerge. Eggs, while a source of ongoing debate, can form part of a balanced diet for most people. It’s essential, though, to consider your entire dietary pattern, emphasizing heart-healthy choices like those found in the DASH and Mediterranean diets.
Avoiding processed meats and sugary breakfast options, while incorporating nutrient-dense foods, can significantly impact your blood pressure management. But remember, it’s not all about diet. A comprehensive approach, involving regular physical activity, stress mana...
Source: The EMT Spot - July 21, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs
Science Snippet: Antioxidants Explained
Many types of fruits, vegetables, and legumes are rich in antioxidants. Credit: iStock.
While at the grocery store, you’ve likely noticed foods with labels saying they contain antioxidants, but what does that mean? In short, antioxidants are substances that may prevent or delay some types of cell damage. Many foods, including fruits and vegetables, naturally produce antioxidants like vitamins C and E, beta-carotene, and selenium. Our bodies also naturally produce antioxidant molecules such as alpha-lipoic acid, glutathione, and coenzyme Q10.
Antioxidants are united by their ability to donate electrons, whi...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - July 5, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Science Snippet Source Type: blogs
Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models.
The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
“We Are Electric” by Sally Adee: Medgadget Interviews the Author
The human body has a deep connection with electricity. The transmission of electrical impulses is responsible for the movement of our limbs, the functioning of our organs, and the formation and recall of memories. The signatures of the various electr...
Source: Medgadget - June 12, 2023 Category: Medical Devices Authors: Scott Jung Tags: Education etc. Exclusive Source Type: blogs
AI ’s role in Healthcare: Exclusive Interview with Catherine Estrampes, President & CEO at GE Healthcare
AI is increasingly being used in healthcare to reduce clinician workloads and improve patient outcomes. AI-driven technologies are helping to automate mundane tasks, freeing up clinicians to focus on more complex clinical decisions. AI-powered tools ...
Source: Medgadget - May 3, 2023 Category: Medical Devices Authors: Alice Ferng Tags: Exclusive Informatics AI medicine GEHealthCare Source Type: blogs
Fight Aging! Newsletter, April 24th 2023
In this study, researchers show that mice lacking a functional ATF4 gene show little to no loss of grip strength and treadmill performance into late life; it is quite an impressive effect size. Assessments of muscle biochemistry do show age-related declines, but to a lesser degree than the controls. How ATF4 knockout functions to produce this outcome is an interesting question. The researchers point out a range of possible downstream and upstream targets that have been implicated in the regulation of muscle growth, but it will clearly require further work to identify the important mechanisms involved.
Aging slowly...
Source: Fight Aging! - April 23, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Farm Bill 2023 and Obesity
This study found U.S. farm policies “have generally small and mixed effects on farm commodity prices, which in turn have even smaller and still mixed effects on the relative prices of more‐ and less‐fattening foods.”Farm subsidy/ nutrition issues are hotly debated, and I have not done a detailed research review. If Congress withdrew subsidies from corn, wheat, soybeans, and rice, would U.S. farming shift toward healthier fruits and vegetables? Are the subsidized crops and related oils a cause of obesity, and has the go vernment given Americans bad nutrition advice about these products for decades, asNina T...
Source: Cato-at-liberty - April 6, 2023 Category: American Health Authors: Chris Edwards Source Type: blogs
Fight Aging! Newsletter, April 3rd 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
5 essential tips to help men prevent prostate cancer
1. Eat a healthy diet rich in fruits, vegetables, and whole grains. Eating a healthy diet is an important way to help prevent prostate cancer. Fruits and vegetables are packed with antioxidants, which can help protect your cells from damage that can lead to cancer. Fruits and vegetables that are particularly beneficial for prostate cancer
Read more…
5 essential tips to help men prevent prostate cancer originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - March 23, 2023 Category: General Medicine Authors: Kevin Jones, MD Tags: Conditions Oncology/Hematology Urology Source Type: blogs
Fight Aging! Newsletter, March 20th 2023
This study also provides the potential for de novo generation of complex organs in vivo.
T Cells May Play a Role in the Brain Inflammation Characteristic of Neurodegenerative Conditions
https://www.fightaging.org/archives/2023/03/t-cells-may-play-a-role-in-the-brain-inflammation-characteristic-of-neurodegenerative-conditions/
Alzheimer's disease, and other forms of neurodegenerative condition, are characterized by chronic inflammation in brain tissue. Unresolved inflammatory signaling is disruptive of tissue structure and function. Here, researchers provide evidence for T cells to become involved in this...
Source: Fight Aging! - March 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, February 27th 2023
This study tested the hypothesis that ischemic vascular repair in aging by Ang-(1-7) involves attenuation of myelopoietic potential in the bone marrow and decreased mobilization of inflammatory cells.
Young or Old male mice of age 3-4 and 22-24 months, respectively, received Ang-(1-7) for four weeks. Myelopoiesis was evaluated in the bone marrow (BM) cells by carrying out the colony forming unit (CFU-GM) assay followed by flow cytometry of monocyte-macrophages. Expression of pro-myelopoietic factors and alarmins in the hematopoietic progenitor-enriched BM cells was evaluated. Hindlimb ischemia (HLI) was induced by ...
Source: Fight Aging! - February 26, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
