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Total 955 results found since Jan 2013.

A Second Cancer
It’s been a long time since I posted anything.   Recently I was diagnosed with a second primary cancer.  I’ve had surgery and am well on the way to recovery. My hematologist and the head and neck cancer specialist agreed it wasn’t necessary for me to undergo aggressive surgery for this cancer, so I didn’t have …
Source: beth's myeloma blog - May 4, 2023 Category: Cancer & Oncology Authors: Beth Tags: Cancer Source Type: blogs

New curcumin myeloma clinical trial
Conclusion: “Curcumin has an efficacy in improving overall remission and decreasing NF-kB, VEGF, TNF-a, and IL-6 levels in myeloma patients.” And so we have more proof…and this proof comes from actual myeloma patients, not from cells grown in a Petri dish. The evidence is piling up! I wonder when (or if!) our myeloma luminaries and organisations are going to wake up to the fact that curcumin has a real potential to help us myeloma folks at every stage of this cancer. If I could, I would tell them (the above luminaries and organisations) to ignore the profits and benefits (international conferences held i...
Source: Margaret's Corner - August 5, 2022 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll curcumin myeloma clinical trial Source Type: blogs

“ Why multiple myeloma returns ” …
That’s the title of an interesting Science Daily article that I came across this morning (and that blog reader Ana also told me about in a comment I read soon afterward, thank you!). Here’s the link: https://www.sciencedaily.com/releases/2022/03/220301131117.htm?utm_source=feedburner&utm_medium=email In a nutshell, a group of researchers at the Charité – Universitätsmedizin Berlin discovered that the culprit to the HUGE problem of drug resistance (non-genetic drug resistance, in particular) in myeloma is the increased production of a protein, the CDK6 protein, which not only activates cell prolifera...
Source: Margaret's Corner - March 2, 2022 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll CDK6 protein in myeloma Source Type: blogs

Celegene REMS Has An App
It’s been a while since I took Pomalyst or Revlimid.  I used to have to make a call to Celgene to take a survey.  The purpose of the survey is just to make sure patients are aware of the safety concerns.  I just got a call from the cancer center pharmacy that I can pick … The post Celegene REMS Has An App first appeared on Beth Morgan Multiple Myeloma Treatment Blog.
Source: beth's myeloma blog - June 21, 2021 Category: Cancer & Oncology Authors: Beth Tags: Myeloma Treatment pomalidomide Pomalyst celgene Source Type: blogs

Evaluation of the Surgical Specimen After Neoadjuvant Systemic Therapy
ConclusionPostneoadjuvant systemic therapy histopathological changes are complex, and careful systematic review of the specimen is required for accurate diagnosis and follow-up treatment. For pathological complete response to be used as an indicator of response to novel therapies, it is essential to have a standardized way in which residual disease is measured and reported. We designed the recommendations specifically for the clinical trial setting; however, they can be optionally incorporated into routine practice because, in our opinion, standardization is most effective when uniformly applied. Hopefully, such standardiz...
Source: Oncopathology - March 23, 2021 Category: Cancer & Oncology Tags: breast Breast Biopsy Procedure breast cancer Source Type: blogs

Peekaboo
Well, about two weeks ago we received the sad but expected news that Peekaboo has an inoperable and malignant nasal tumor located on the left side of her face, the side that has become deformed. The vets refer to it as a sarcoma. Because of her age (she’s almost 14 years old) and other factors, the vets and Stefano and I are in agreement: we’ll do nothing, except monitor her and (try to) make sure she’s not in pain (although it’s very difficult to figure out if a cat is in pain or not)… I’ve begun giving her curcumin, mixed in with her wet food, but it’s way too early (just a few d...
Source: Margaret's Corner - March 1, 2021 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll feline nasal cancer feline sarcoma Source Type: blogs

Dieneke
A few days ago I discovered that my blog reader/friend Dieneke Ferguson had died months ago, in October. She had been diagnosed with MM in her 50s for which she had undergone many conventional treatments. When she was left with no options (but the final one!!!), many years ago, she came across my blog, got in touch with me, and began taking curcumin, which managed to stabilize her so much so that in 2018 she was interviewed by BBC Radio 4. That interview, if my memory serves me correctly, was picked up by other news agencies. Dieneke became quite well-known. Unfortunately, she later developed ovarian cancer. The last time ...
Source: Margaret's Corner - February 9, 2021 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll Source Type: blogs

My Benjamin Hartman Story
“I need intravenous Beefsteak,” I texted my forever-Beefsteak date Ben Hartman, who others called Benjie or Bean or sometimes Boozey, and who I called Kryptonite or sometimes Sushi Ben. “See you there at 6:30,” he texted back. Since meeting in 2014, we each accommodated the other when it came to Beefsteak — a fast-casual restaurant near George Washington University that served paleo-friendly fare before paleo was cool and offered outdoor seating long before covid-19. My gcalendar archive shows that we made seven Beefsteak dates in advance, though that’s a fraction of our total as most stemmed fro m mi...
Source: cancerslayerblog - December 5, 2020 Category: Cancer & Oncology Tags: death life lessons Source Type: blogs

Too much licorice may kill you
This morning, thanks to a friend’s post on Facebook, I read an Associated Press article, picked up and published by NBC News, that REALLY shocked me. Here’s the link: https://www.nbcnews.com/news/us-news/daily-black-licorice-habit-kills-massachusetts-construction-worker-n1240902?fbclid=IwAR1kiMGaCEQGdDrGjyVkkdy1l0MT8nNSAByFBnzqdYQFxkqYGAuQIjNgrcM Is it possible for someone to DIE from eating too much licorice??? The incredible answer is…yes. It happened to a 54-year-old man in Massachusetts, U.S.A. He had been eating A LOT of licorice, a bag and a half apparently!!!, every day for a few weeks before he co...
Source: Margaret's Corner - September 25, 2020 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll death licorice. glycyrrhizic acid Source Type: blogs

A new curcumin-myeloma study
Unfortunately, the full study, just published in the journal Anti-Cancer Agents in Medicinal Chemistry, is not available online for free, but the abstract gives us a good idea of its content: https://pubmed.ncbi.nlm.nih.gov/32951583/ The abstract begins with a description of multiple myeloma, stuff we already know or should know…But then I noticed two words in the following sentence: “MM is almost incurable, and patients faced to this disease eventually relapse.” Did you see that? “Almost” and “incurable.” That “almost” suggests that there is a form of myeloma that is c...
Source: Margaret's Corner - September 23, 2020 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll cancer curcumin myeloma Source Type: blogs

Reaching out to all MGUS, SMM, MM patients and caregivers
Last week I was contacted by Stephen Quinn, a Ph.D. student at Queen’s University in Belfast. He informed me about a study called IMPaCCT whose intent is to look at the effect that the current Covid-19 crisis has had, and is having, on pre-cancer, cancer and rare disease patients and their caregivers. The researchers, which include Stephen, hope to be able to use this data to inform patients and caregivers, as well as publish their findings in scientific journals. He asked for my help in reaching out to smoldering myeloma and MGUS patients. Of course! So, how can we help? By taking their online SURVEY. I am about to do ...
Source: Margaret's Corner - May 25, 2020 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll ImpaCCt study Source Type: blogs

Did I have Covid-19?
A few blog readers have suggested to me, privately, that the awful flu I had back in early January might have been Covid-19. But well before I had read their suggestions, that same thought had occurred to me, too, in the early days of the outbreak here in Italy. So this morning I decided to write a post about it, just for the record. I certainly did have some of the Covid-19 symptoms, namely: fatigue (probably my very first symptom) sore throat (also an early symptom) terrible intestinal woes (ditto as above) high fever…a very high fever aches, of course nasal congestion cough (see below) and, finally, pneumonia, ye...
Source: Margaret's Corner - April 27, 2020 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll coronavirus covid-19 Source Type: blogs

Treat so-called “ high-risk ” smoldering myeloma … Yes or No?
My (predictable) answer is “NO, absolutely NOT.” Not until you begin having CRAB symptoms. But first things first… I began writing this post last week, then I just had too many things to do so I didn’t finish my draft. Then, yesterday morning, before going to work, I came across an article by Dr. Brian Durie (I don’t think I need to explain who he is!) making some of the points I had already made in my draft, BUT from the point of view of a world-famous hematologist. So I decided to cut my draft in half and give you the link to Dr. Durie’s piece: http://bit.ly/2WWwsX9 But, of course, I ...
Source: Margaret's Corner - November 7, 2019 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll HR SMM lenalidomide Source Type: blogs