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Total 418 results found since Jan 2013.

Discussing the Accelerated Aging of Cancer Survivors
It is well known that cancer survivors who underwent chemotherapy or radiotherapy exhibit a shorter life expectancy, greater chance of unrelated cancer incidence, and greater risk of age-related disease. The most reasonable hypothesis at present is that these undesirable outcomes are the result of an increased burden of senescent cells. Historically, cancer treatments have been in large part designed to force cancerous cells into senescence, those that are not killed outright by the therapy. Since these cancer therapies are toxic to cells, they also tend to cause off-target cell death and senescence. It is possible that si...
Source: Fight Aging! - July 12, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

A Worse Functional Decline with Age is Observed in Cancer Survivors
In conclusion, cancer survivors, especially older individuals, demonstrate greater odds of and accelerated functional decline, suggesting that cancer and/or its treatment may alter aging trajectories.
Source: Fight Aging! - August 12, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Cancer Not As Scary?
How scary is a breast cancer, or any other type of cancer diagnosis these days? Thisarticle, Thanks to advances, diagnosis of breast cancer isn ’t as frightening as it was, claims it ' s not as scary as it used to be due to advances in diagnosis and treatment. However I beg to disagree. That is not the only reason. And societally, we have not changed enough.Do you remember in the 1970s and earlier when people didn ' t talk about cancer? No, they whispered about it. So-and-so has cancer.... when ' s the funeral? Nice sequence there. But that is how life was. No one talked about cancer because it was a death sent...
Source: Caroline's Breast Cancer Blog - February 25, 2018 Category: Cancer & Oncology Tags: breast cancer breast cancer treatment cancer diagnosis Source Type: blogs

Zytiga Lowers PSA in men with high-risk prostate cancer, at a cost in side-effects
Prostate cancer survivors during the era 2005-2013, as you'll see from our tag cloud (sidebar), were bombarded by Dendreon's controversial campaign to speed FDA approval of its immunotherapy vaccine Provenge. Since then, Provenge hype has calmed down, while the push for Abiraterone acetate (Zytiga) has heated up. Abiraterone (generic name) aka  Zytiga (brand name) is ...continue reading Zytiga Lowers PSA in men with high-risk prostate cancer, at a cost in side-effects
Source: psa-rising.com/blog - May 24, 2015 Category: Cancer & Oncology Authors: Jacquie Strax Tags: Abiraterone CRPC Prostate Cancer Side Effects Zytiga Source Type: blogs

Cancer Immunotherapy
That's a mouthful. But Science Magazine has named Cancer Immunotherapy as their breakthrough for the year. So what exactly is that?"“Immunotherapy marks an entirely different way of treating cancer — by targeting the immune system, not the tumor itself,” Science said... Based on the idea that the immune system can be trained to attack tumors in the same way that it targets infectious agents, cancer immunotherapy exploits the ability to harness different types of immune cells circulating in the body."Researchers have already made some progress with this way of thinking with both melanoma and leukemia. They have plans ...
Source: Caroline's Breast Cancer Blog - January 2, 2014 Category: Cancer Tags: award cancer research progress Source Type: blogs

Advocating for Senolytics to Prevent Accelerated Aging Resulting from Cancer Treatment
Chemotherapy and radiotherapy remain the presently dominant forms of cancer treatment. Immunotherapies are making slow inroads, but remain a minority of all treatments. Both chemotherapy and radiotherapy kill cells and force cells into senescence, cancerous cells and otherwise. They are a balance struck between killing the cancer and killing healthy tissue, and are are not pleasant at all for the patient. Cancer survivors have a significantly reduced life expectancy, as large as that resulting from life-long smoking, and evidence strongly suggests that this is due to a significantly increased burden of>senescent cells left...
Source: Fight Aging! - May 11, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Cancer Survivors Exhibit a Significantly Higher Risk of Cardiovascular Disease
The dominant cancer therapies of chemotherapy and radiotherapy have not yet been replaced by immunotherapies for more than a handful of cancer types. These classes of therapy produce a significantly increased burden of senescent cells in patients; one of the goals of cancer therapy is to drive cancerous cells into senescence, those that cannot be killed. These additional senescent cells in turn accelerate the progression of degenerative aging. The advent of senolytic therapies to clear senescent cells from aged tissues will make a sizable difference to these patients. More effort should be undertaken today to enable patien...
Source: Fight Aging! - July 4, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Six Reasons Why Cancer is an Emotional Diagnosis Too
By Cynthia Hayes, Author, The Big Ordeal: Understanding and Managing the Psychological Turmoil of Cancer No matter when you hear the words, “You’ve got cancer,” you are bound to have an emotional reaction. The news is devastating, and the physical challenges that lie ahead are very real. But, unfortunately, that is only half the story. Cancer is an emotional diagnosis too, and our psychological and physical responses to the disease and its treatment are intertwined, coloring the entire experience. Why is cancer so emotional? We fear we will die For millennia, cancer has been a death sentence. So even though ...
Source: PickTheBrain | Motivation and Self Improvement - February 22, 2021 Category: Consumer Health News Authors: Cynthia Hayes Tags: featured health and fitness philosophy psychology self-improvement cancer healing illness pickthebrain self improvement Source Type: blogs

Newer skin cancer treatments improve prognosis for those with cutaneous melanoma
Cutaneous melanoma, also called malignant melanoma, is the type of skin cancer that is most likely to spread to other parts of the body. Though melanoma accounts for only about 1% of skin cancers, it is responsible for more than 90% of skin cancer-related deaths. But thanks to developments in skin cancer treatment (mostly in the last decade), patients with melanoma have much better chances of living longer. What is a melanoma? Melanoma involves the uncontrolled growth of a type of cell known as a melanocyte. One of the most important functions of a normal melanocyte is to protect your skin from the sun’s damaging ultravi...
Source: Harvard Health Blog - February 3, 2020 Category: Consumer Health News Authors: Dominic Wu, MD Tags: Cancer Skin and Hair Care Source Type: blogs

Persuing ASCO 2017 - AKA Time for Lorazepam
Photo from ASCO Mediakit. © ASCO/Danny Morton 2017TheAnnual Meeting of the American Society of Clinical Oncology was last week. It ’s been my observation over the years that much of the best palliative-oncology and supportive-oncology research is presented at ASCO each year, before it’s actually published (if it ever gets published).  So I always dig through the palliative/EOL/supportive/psychooncology abstracts each year to see what ' s happening. Below is a gently annotated list of the abstracts that caught my eye the most, for your perusal and edification. Undoubtedly, these are my idiosyncratic choices, ...
Source: Pallimed: A Hospice and Palliative Medicine Blog - June 8, 2017 Category: Palliative Care Tags: ASCO cancer oncology pallonc research research issues rosielle WaPo Source Type: blogs

Is it Possible to Safely Tip the Balance in Cancer Treatment Towards Cell Death Rather than Cell Senescence?
Most cancer treatments produce a lot of senescent cells in the course of killing cancerous cells. This is thought to be the primary reason as to why cancer survivors have a reduced life expectancy and greater burden of age-related disease. Senescent cells secrete disruptive, inflammatory signals that harm tissue function when consistently present. Growing numbers of senescent cells in old tissues are an important contribution to degenerative aging. The straightforward approach to this issue would be to treat cancer patients with senolytic therapies to clear senescent cells after the anti-cancer treatment is complete...
Source: Fight Aging! - September 13, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Senolytic Therapies to Clear Senescent Cells Should Benefit Cancer Patients
It is well known that the present dominant approaches to cancer therapy - meaning toxic, damaging chemotherapy and radiotherapy, only slowly giving way to immunotherapy - produce a significant burden of senescent cells. Indeed, forcing active cancer cells into senescence is the explicit goal for many treatments, and remains an aspirational goal for a large fraction of ongoing cancer research. Most senescent cells self-destruct, or are destroyed by the immune system, but some always linger - and more so in older people, due to the progressive incapacity of the immune system. An immune system that becomes ineffective in supp...
Source: Fight Aging! - June 6, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

ASCO 2014 Is A Wrap: If Immunotherapy Is The Queen Of The Ball, Then Panomics Holds The Keys To The Kingdom
As in years past, the trip home from the Annual Meeting of the American Society of Clinical Oncology in Chicago gives me a moment to reflect on what I have heard and hopefully learned over the past five days. This meeting is a whirlwind of activity and information, far too much for any one person to absorb and process. You can be focused on one topic, you can be general, and you can hear new cutting edge research or be educated on topics of general interest in cancer. You can go to the exhibit hall and be overwhelmed by the booths and displays (I tend not to go there, but obviously many others do). I suspect you get the id...
Source: Dr. Len's Cancer Blog - June 4, 2014 Category: Cancer Authors: Dr. Len Tags: Access to care Breast Cancer Cancer Care Cervical Cancer Heatlh Information Technology Lung Cancer Media Medications Melanoma Other cancers Research Skin Cancer Treatment Source Type: blogs

Stomach Cancer Stage 4 Treatment
Stomach cancer stage 4 is a complex diagnosis. It is the stage of cancer that requires specific treatment options. Is surgery an option for patients with stomach cancer stage 4? Stage 4 stomach cancer is characterized by rapid tumor growth, metastasizing to regional lymph nodes and distant organs (liver, bones, pancreas, less often lungs). With the development of metastases in other organs, characteristic symptoms occur such as jaundice and liver failure with liver damage, ascites with metastases in the peritoneum, bowel obstruction with metastases in the small intestine, etc. Therefore, at the advanced stages, ga...
Source: PickTheBrain | Motivation and Self Improvement - January 22, 2021 Category: Consumer Health News Authors: Booking Health Tags: health and fitness self-improvement cancer stomach cancer treatment Source Type: blogs

About that Cancer Moonshot
By KIM BELLARD Joe Biden hates cancer.  He led the Cancer Moonshot in the Obama Administration, and, as President, he reignited it, vowing to cut death rates in half over the next 25 years.  Last month, on the 60th anniversary of President Kennedy’s historic call for an actual moonshot, he vowed “to end cancer as we know it. And even cure cancers once and for all.” But, as several recent studies show, cancer is still surprising us.  ————— Our body has its own defenses against cancer, such as T-cells, and great strides have been made in cancer therapies, includi...
Source: The Health Care Blog - October 6, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Public Health Biden Cancer Cancer Moonshot Source Type: blogs