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How Breast Cancer Changed My Life – guest post
Okay, it’s been almost a month since my last confession, er, entry. Time goes so rapidly now. I work five days a week. I know a lot of people do, but I have been off for seven years thanks to cancer and stem cell transplant. My mother moved in with us after her fall in March. I have had the grand-kids a couple times a week. And Spring came early here in the midwest. We have a huge garden that was already threatening to go to weeds. I bought 130 bags of mulch last week. So I have been weeding, feeding, digging, spraying, planting and transplanting, mowing. And this is not to mention building a 16&#...
Source: Being Cancer Network - May 7, 2012 Category: Cancer Authors: admin Tags: Guest Post * Living with Cancer Breast cancer Grace Survivorship Source Type: blogs
A Gala, a Trophy, and $50,000 for Cancer Research
Read this first: I Hope My Friends Forgive Me: What It’s Like to FundraiseIn less than 20 minutes at the rehearsal for candidates before the Man & Woman of the Year Grand Finale Gala, I broke protocol and walked onstage to meet myself.Candidates were instructed to arrive to rehearsal fully dressed. My custom-tailored super fly tuxedo direct from Vietnam was delayed in production for three weeks, forcing me to rent a slim-fit tux from Men’s Wearhouse. Two lessons for you aspiring economists: being slim costs extra (my tux rental cost $180 versus a much cheaper standard fit), and that $180 is called a sunk cost. Temp...
Source: I've Still Got Both My Nuts: A True Cancer Blog - June 24, 2014 Category: Cancer Tags: a day in my life man of the year Source Type: blogs
Discussing the Accelerated Aging of Cancer Survivors
It is well known that cancer survivors who underwent chemotherapy or radiotherapy exhibit a shorter life expectancy, greater chance of unrelated cancer incidence, and greater risk of age-related disease. The most reasonable hypothesis at present is that these undesirable outcomes are the result of an increased burden of senescent cells. Historically, cancer treatments have been in large part designed to force cancerous cells into senescence, those that are not killed outright by the therapy. Since these cancer therapies are toxic to cells, they also tend to cause off-target cell death and senescence. It is possible that si...
Source: Fight Aging! - July 12, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
A Connection Between the Zika Virus and Curing Brain Cancer?
Not long ago, Zika virus was dominating headlines. A new infection was hardly ever heard about before then, yet is now affecting hundreds of thousands of people in Latin America, causing disfiguration and microcephalia in new-born babies. Microcephalia is caused by severe delayed and abnormal development of the brain, resulting in the range of intellectual disability, dwarfism, poor motor functions and speech. With no cure or even preventive vaccination available, many women in the most affected regions were reportedly considering postponing any planned pregnancies.
The virus was actually discovered back in 1947 in Zika fo...
Source: World of Psychology - October 28, 2017 Category: Psychiatry & Psychology Authors: Psych Central Staff Tags: Brain and Behavior Brain Blogger Health-related Publishers Research brain cancer Delivery glioblastoma Immune System microcephalia Pregnancy Sexual Contact stem cells Zika virus Source Type: blogs
Advocating for Senolytics to Prevent Accelerated Aging Resulting from Cancer Treatment
Chemotherapy and radiotherapy remain the presently dominant forms of cancer treatment. Immunotherapies are making slow inroads, but remain a minority of all treatments. Both chemotherapy and radiotherapy kill cells and force cells into senescence, cancerous cells and otherwise. They are a balance struck between killing the cancer and killing healthy tissue, and are are not pleasant at all for the patient. Cancer survivors have a significantly reduced life expectancy, as large as that resulting from life-long smoking, and evidence strongly suggests that this is due to a significantly increased burden of>senescent cells left...
Source: Fight Aging! - May 11, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Potential for Senolytics and Other Senotherapies to Improve Outcomes in Cancer Therapies
Cellular senescence is a double-edged sword in the matter of cancer. The state of senescence is a growth arrest coupled with pressure to self-destruct and a call to the immune system to destroy the senescent cell. As such it serves as a first line of defense against cancer. Most cancer treatments force large numbers of cancerous cells into senescence, in addition to causing outright cell death, shutting down their ability to replicate. Unfortunately, the presence of too many senescent cells is harmful in and of itself, as their signaling produces chronic inflammation, disrupts tissue function throughout the body, and makes...
Source: Fight Aging! - January 28, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
My Favorite Neighbor I’ve Never Met
My spine shivered when I heard Drew puking. Unlike my once-a-day vomits that mimicked the Tambora volcanic eruption of 1815, Drew’s were fast, graceful and plentiful. I tracked my “Puke Count” on a whiteboard with tallies. Drew’s Puke Count would require an entire wall.Drew and I shared a wall because he was my next-door neighbor at the Pediatric Blood and Marrow Transplant Center at the University of Minnesota. That is where I received my umbilical cord stem cell transplant to treat myelodysplasia when I was 19 years old. I never formally met Drew, though I knew much about him by prying my nurses, instructing my d...
Source: I've Still Got Both My Nuts: A True Cancer Blog - June 8, 2014 Category: Cancer Tags: cancer treatment man of the year Source Type: blogs
Persuing ASCO 2017 - AKA Time for Lorazepam
Photo from ASCO Mediakit. © ASCO/Danny Morton 2017TheAnnual Meeting of the American Society of Clinical Oncology was last week. It ’s been my observation over the years that much of the best palliative-oncology and supportive-oncology research is presented at ASCO each year, before it’s actually published (if it ever gets published). So I always dig through the palliative/EOL/supportive/psychooncology abstracts each year to see what ' s happening. Below is a gently annotated list of the abstracts that caught my eye the most, for your perusal and edification. Undoubtedly, these are my idiosyncratic choices, ...
Source: Pallimed: A Hospice and Palliative Medicine Blog - June 8, 2017 Category: Palliative Care Tags: ASCO cancer oncology pallonc research research issues rosielle WaPo Source Type: blogs
Senolytic Therapies to Clear Senescent Cells Should Benefit Cancer Patients
It is well known that the present dominant approaches to cancer therapy - meaning toxic, damaging chemotherapy and radiotherapy, only slowly giving way to immunotherapy - produce a significant burden of senescent cells. Indeed, forcing active cancer cells into senescence is the explicit goal for many treatments, and remains an aspirational goal for a large fraction of ongoing cancer research. Most senescent cells self-destruct, or are destroyed by the immune system, but some always linger - and more so in older people, due to the progressive incapacity of the immune system. An immune system that becomes ineffective in supp...
Source: Fight Aging! - June 6, 2019 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Farrah Fawcett death
Give your condolences here: Farrah Fawcett death, June 25, 2009. Watch her home video taped documentary of her last 2,5 years battling cancer including seeking alternative cancer treatments in Germany. Farrah Fawcett died surrounded with her loved ones Farrah Fawcett dies after a 2,5 year battle against anal cancer. According to the American […]
Source: Metastatic liver cancer - June 26, 2009 Category: Cancer Authors: Kim Tags: Alternative CANCER TREATMENTS a wing & a prayer condolences death of farrah fawcett embryonic stem cell cancer treatment farah fawcett cancer farrah fawcett cancer farrah fawcett cancer update farrah fawcett close to death farrah fawcett Source Type: blogs
The Little B****rds
I'm sorry I just don't have a better word for cancer cells which spread.We'll just call them the little B's. Anyway, some new research has been done on metastatic cancer cells. The goal is to find them and snuff them out, obviously.Dr Rauscher of the Wistar Institute's cancer center recently discussed some new information discovered about breast cancer metastatic cells:"Solid tumors such as breast cancers grow their own blood supply, a process called angiogenesis. It's clear that breast tumors shed malignant cells into the bloodstream. And it's clear that most of these cells get killed by the stress of shearing off from th...
Source: Caroline's Breast Cancer Blog - June 30, 2016 Category: Cancer & Oncology Tags: breast cancer cancer cells cancer research metastatic cancer Source Type: blogs
The Death of Cancer: Book Review and Reflections
By CHADI NABHAN MD, MBA, FACP
Some books draw you in based on a catchy title, a provocative book jacket, or familiarity with the author. For me, recollections of medical school primers written by the renowned lymphoma pioneer Vincent DeVita Jr. and my own path as an oncologist immediately attracted me to “The Death of Cancer.” I felt a connection to this book before even reading it and prepped myself for an optimistic message about how the cancer field is moving forward. Did I get what I bargained for?
Co-authored with his daughter, Elizabeth DeVita-Raeburn, DeVita brings us back decades ago to when he had just st...
Source: The Health Care Blog - January 1, 2019 Category: Consumer Health News Authors: matthew holt Tags: Health Care Books Physicians Book Review Chadi Nabhan Chemotherapy Oncology randomized controlled trials The Death of Cancer Vincent DeVita Source Type: blogs
Another T-Cell Advance Against Cancer
The technique of using engineered T cells against cancerous cells may be about to explode ever more than it has already. One of the hardest parts of getting this process scaled up has been the need to extract each patient's own T cells and reprogram them. But in a new report in Nature Biotechnology, a team at Sloan-Kettering shows that they can raise cells of this type from stem cells, which were themselves derived from T lymphocytes from another healthy donor. As The Scientist puts it:
Sadelain’s team isolated T cells from the peripheral blood of a healthy female donor and reprogrammed them into stem cells. The researc...
Source: In the Pipeline - August 14, 2013 Category: Chemists Tags: Cancer Source Type: blogs
Delete Blood Cancer: What You May Not Know About Bone Marrow Donation
We all know about blood drives and the importance of blood and platelet donations to save lives. And millions of people are registered organ donors (usually when they get their driver’s license). But did you know that there is another renewable, life-saving resource you could give? It’s your blood stem cells/bone marrow. Only 11 million Americans are registered with the National Marrow Donor Program to help save lives if their blood stem cells match a person fighting any one of 70 blood cancers and diseases.
Each year, nearly 20,000 people are in need of blood stem cell/bone marrow transplants as their last hope for ...
Source: Disruptive Women in Health Care - July 22, 2014 Category: Consumer Health News Authors: DW Staff Tags: Access Advocacy Cancer Consumer Health Care Patients Publc Health Source Type: blogs
