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The people who will cure cancer are the patients
Sometimes I tell people I’m learning how to treat cancer, and their first question is ‘why haven’t we cured cancer yet?’ We will.  It’s coming. In medicine we’re much better at treating infections than cancer, but it wasn’t always that way: We didn’t know washing your hands before delivering a baby wassafer for women until 1847. The concept of a germ was proposed in 1870. The first vaccine was made in 1879. Penicillin didn’t show up until 1928. The last fatal case of smallpox was reported in 1978, and smallpox was declarederadicated in 1979. The AIDS epidemic began in 1981 when five previously...
Source: Kevin, M.D. - Medical Weblog - December 25, 2014 Category: Journals (General) Authors: Tags: Conditions Cancer Source Type: blogs

Fight Aging! Newsletter, May 18th 2020
This study provides direct evidence for the contribution of gut microbiota to the cognitive decline during normal aging and suggests that restoring microbiota homeostasis in the elderly may improve cognitive function. On Nutraceutical Senolytics https://www.fightaging.org/archives/2020/05/on-nutraceutical-senolytics/ Nutraceuticals are compounds derived from foods, usually plants. In principle one can find useful therapies in the natural world, taking the approach of identifying interesting molecules and refining them to a greater potency than naturally occurs in order to produce a usefully large therape...
Source: Fight Aging! - May 17, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, September 19th 2022
Conclusion Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life. Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases. Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Heart disease and cancer are responsible for nearly half of all deaths in the U.S., report says - LA Times
http://www.latimes.com/science/sciencenow/la-sci-sn-causes-of-death-20160629-snap-story.htmlHeart disease and cancer are responsible for nearly half of all deaths in the U.S., report saysWhat are the most common ways to die in America? The answer depends on how old you are, whether you ' re a man or a woman, and your racial and ethnic background, a new report shows.Alzheimer ' s disease accounted for 5% of deaths among U.S. women, for instance, but only 2.1% of deaths among men. Accidents and unintentional injuries caused 39.7% of deaths among people between the ages of 10 and 24, but only 7.4% of deaths for adults between...
Source: Dr Portnay - August 14, 2016 Category: Cardiology Authors: Dr Portnay Source Type: blogs

Fight Aging! Newsletter, November 27th 2017
We examined associations between mortality and accelerometer-measured PA using age-relevant intensity cutpoints in older women of various ethnicities. The results support the hypothesis that higher levels of accelerometer-measured PA, even when below the moderate-intensity threshold recommended in current guidelines, are associated with lower all-cause and CVD mortality in women aged 63 to 99. Our findings expand on previous studies showing that higher self-reported PA reduces mortality in adults aged 60 and older, specifically in older women, and at less than recommended amounts. Moreover, our findings challenge th...
Source: Fight Aging! - November 26, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Health Information Technology: A Guide to Study Design For the Perplexed
This study, which was widely reported in the news media and influenced policy, found significant differences in the rate of flu-related deaths and hospitalizations among the vaccinated elderly compared with their unvaccinated peers. Although it controlled for certain easy-to-measure differences between the 2 groups, such as age, sex, and diabetes, it did not account for other more difficult-to-measure “healthy user” factors that affect the well-being of the elderly, such as their socioeconomic status, diet, exercise, and adherence to medical treatments and advice. The cohort design has long been a staple in studies of...
Source: The Health Care Blog - September 13, 2015 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, November 4th 2019
In this study, we hypothesized that moderately and chronically reducing ACh could attenuate the deleterious effects of aging on NMJs and skeletal muscles. To test this hypothesis, we analyzed NMJs and muscle fibers from heterozygous transgenic mice with reduced expression of the vesicular ACh transporter (VAChT), VKDHet mice, which present with approximately 30% less synaptic ACh compared to control mice. Because ACh is constitutively decreased in VKDHet, we first analyzed developing NMJs and muscle fibers. We found no obvious morphological or molecular differences between NMJs and muscle fibers of VKDHet and contro...
Source: Fight Aging! - November 3, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 14th 2021
In conclusion, a number of high-income countries, changes in health expectancies over time have not kept pace with the growth in life expectancy. That is, people are living longer but disability and poor health are occupying an increasing proportion of later life. Our findings suggest that countries still need to make significant progress to achieve the WHO's Decade of Healthy Ageing goal of healthier, longer lives for all. Progress on Understanding Why Human Growth Hormone Receptor Variants are Associated with Greater Longevity https://www.fightaging.org/archives/2021/06/progress-on-understanding-why-human-gro...
Source: Fight Aging! - June 13, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The importance of recognizing immunodeficiency
On a cold, blustery Cleveland day when I was a resident, a forty-year-old man walked into our infectious disease clinic at the Cleveland Clinic. The patient was undergoing routine visits in preparation for a kidney transplant. This poor man had been hospitalized six months earlier at another hospital where he caught a terrible infection and was readmitted in septic shock and multi-organ failure. Luckily he survived, but in the process lost some of his toes as well as his kidney function. Thus, he was now on dialysis and awaiting a new kidney. The organism to blame was streptococcus pneumoniae, which causes pneumonias and e...
Source: Kevin, M.D. - Medical Weblog - July 3, 2014 Category: Journals (General) Authors: Tags: Conditions Specialist Source Type: blogs



Infant Paralyzed and Brain-Damaged After 6-Month Vaccinations, Doctors Threatened Parents to Further Vaccinate Their Daughter
Conclusion There are many legitimate reasons why parents don’t want their child subjected to what is in any vaccine. We are outraged at the disregard for Cerenity’s life and what her family is going through. In a situation such as what happened to Cerenity, it is absurd doctors would blatantly ignore Cerenity’s vaccine reactions and tell her parents to continue vaccinating her. We hope Cerenity will get the necessary treatment to heal from these vaccine-related injuries. If you have experienced a similar situation and have helpful advice to offer, please reach out to VacTruth, to get in touch with Cerenity’s mother...
Source: vactruth.com - April 2, 2016 Category: Allergy & Immunology Authors: Augustina Ursino Tags: Augustina Ursino Human Top Stories adverse reactions Cerenity Escamilla chiari malformation hypertonic dystonia infant paralysis transverse myelitis truth about vaccines vaccine injury Source Type: blogs



2-Month Old Infant Suffered Apnea and Died Following 8 Vaccines
Conclusion After watching their son get buried, Cash’s parents were thrown into a world they didn’t know much about. They were now another set of grieving parents who senselessly lost their child due to medical practices recommended under a doctor’s care. Vaccines are being ignored when compiling infant mortality data. In 2013, Cash Dewayne Thomas was one of 23,440 babies who died in the United States before reaching their first birthday, according to the latest infant mortality data published in 2016. [19] About 11,300 newborns die within their first day of life, many soon after receiving their first hepatitis B vac...
Source: vactruth.com - June 16, 2016 Category: Allergy & Immunology Authors: Augustina Ursino Tags: Augustina Ursino Human Top Stories apnea Cash Dewayne Thomas Jesse Dewayne Thomas newborn vaccines truth about vaccines Vaccine Death Whitney Hill Source Type: blogs

COVID-19: Physicians in Shackles
By ANISH KOKA, MD A number of politically tinged narratives have divided physicians during the pandemic. It would be unfortunate if politics obscured the major problem brought into stark relief by the pandemic: a system that marginalizes physicians and strips them of agency. In practices big and small, hospital-employed or private practice, nursing homes or hospitals, there are serious issues raising their heads for doctors and their patients. No masks for you When I walked into my office Thursday, March 12th, I assembled the office staff for the first time to talk about COVID.  The prior weekend had been awa...
Source: The Health Care Blog - May 2, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Physicians Anish Koka medical autonomy Pandemic Source Type: blogs

Post #55 COVID-19 Vaccine for 12 to 15 Year Old Adolescents
The Pfizer vaccine will soon be offered to 12-15 year olds, raising a mild conundrum for parents.Should they skip the vaccine, given that most children have fared well when infected with COVID-19 (many already having been infected)?  Or should they immunize their child(ren), even though the vaccine is relatively new and doesn ’t have a long track record?Vaccines have had their missteps, most notably the recalled RotaShield immunization in 1999. However, the recall of RotaShield and the recent temporary pause of the Johnson&Johnson COVID-19 vaccine should instill confidence in the robustness and capability o...
Source: A Pediatrician's Blog - May 8, 2021 Category: Pediatrics Source Type: blogs

Measles: The forgotten killer
As a medical student, the place I dreaded most was the ward at the children’s hospital where they kept the chronic ventilator patients. Unlike the other floors, where there was shouting and laughter and tears, and all the commotion and turbulence of youth, here it was dark and lifeless and eerie, with no sound except the hum of the ventilators, and the rattle of air being forced through plastic tubes. It was a place of failure and defeat, the desolate aftermath of some vast and tragic battle. An unexpected aftermath of measles My patient was a teenager who had been in a coma for years. His limbs had stubbornly twisted up...
Source: Harvard Health Blog - May 23, 2019 Category: Consumer Health News Authors: John Ross, MD, FIDSA Tags: Children's Health Infectious diseases Men's Health Vaccines Women's Health Source Type: blogs