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Vaccination: Ebola Vaccine

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How Firestone controlled Ebola virus disease in Liberia
When the first case of Ebola virus infection was detected at the Firestone Liberia, Inc. rubber tree plantation in March of this year, the company needed to prevent the virus from spreading among their 8,500 employees. The company established an incident management system, developed procedures for early detection of infection, enforced infection control guidelines, and provided different levels of management for contacts depending on their exposure. The company did a remarkable job of isolating and caring for patients and limiting transmission to health care workers and family members. A description of this program, just i...
Source: virology blog - October 21, 2014 Category: Virology Authors: Vincent Racaniello Tags: Information ebola virus ebolavirus Firestone Liberia Inc. infection control rubber tree plantation viral virology Source Type: blogs

Long-term effects of Ebolavirus infection
This study only included adults; children who have recovered should also be examined as their health care needs may be different. These results confirm that there are long-term sequelae of Ebolavirus infection. The basis for the complications is not known, but is likely a consequence of tissue damage due to viral replication and the immune response. Whether or not virus was present in the patients was not determined. However it is known that Ebolavirus can persist in the testicles and eye long after it is absent from serum. Other serious viral infections are also accompanied by long term health effects. For example, 29% of...
Source: virology blog - June 19, 2015 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information acute arthralgia Ebola ebolavirus long term myalgia persistent symptoms uveitis viral Source Type: blogs

Ebolavirus vaccines and antivirals
As the epidemic of Zaire ebolavirus in Western Africa continues (1,779 cases and 961 deaths in four countries), many are questioning why there are no means of preventing or stopping infection. In the past two decades there has been substantial research into developing and testing active and passive vaccines and antiviral drugs, although none have yet been licensed for use in humans. Using antibodies to treat infection with ebolaviruses with antibodies is probably the best known therapy, because it was used to treat a two Americans who were infected while working in Liberia. They received a mixture of three monocl...
Source: virology blog - August 8, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information antiviral ebola virus ebolavirus filovirus Guinea hemorrhagic fever Liberia monoclonal antibody therapy Sierra Leone vaccine ZMapp Source Type: blogs

Could Reston virus be a vaccine for Ebola virus?
I have received many questions about whether immunizing with Reston virus could protect against infection with Ebola virus. Usually the question comes together with the statement ‘because Reston virus does not cause disease in humans’. I can think of two reasons why a Reston virus vaccine is not a good idea. There have been very few confirmed human infections with Reston virus (4 according to Fields Virology 6th Edition), and although these individuals did not show signs of disease, the number is too small to make any conclusions. For example, if the case fatality ratio of Reston virus in humans were 1%, we mi...
Source: virology blog - October 23, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information Bundibugyo ebola virus ebolavirus Reston Sudan Tai Forest vaccine viral Source Type: blogs

COVID-19: Physicians in Shackles
By ANISH KOKA, MD A number of politically tinged narratives have divided physicians during the pandemic. It would be unfortunate if politics obscured the major problem brought into stark relief by the pandemic: a system that marginalizes physicians and strips them of agency. In practices big and small, hospital-employed or private practice, nursing homes or hospitals, there are serious issues raising their heads for doctors and their patients. No masks for you When I walked into my office Thursday, March 12th, I assembled the office staff for the first time to talk about COVID.  The prior weekend had been awa...
Source: The Health Care Blog - May 2, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Physicians Anish Koka medical autonomy Pandemic Source Type: blogs

Can Gingko and Turmeric Help Stop Ebola?
Summary There is no known pharmaceutical currently available that specifically treats Ebola disease. One treatment modality that should be considered is the use of herbal medicines, which have both centuries old anecdotal success as well as recent modern biochemical and formal research rationales for their use. Five areas of action that could be addressed by the herbal medicines as it relates to Ebola would be: VP24/immune system evasion GP protein/replicatio; herbal strategies effective against similar hemorrhagic disease beneficial modulation of patient immune and inflammatory response systems prophylactic use for heal...
Source: Inside Surgery - August 1, 2014 Category: Surgery Authors: Editor Tags: Infectious Disease ayurvedic baicalen cathepsin b dengue Ebola gingko herb Quercetin resveratrol rosemary sage st johns work turmeric Source Type: blogs

Illuminating Biology
This time of year, lights brighten our homes and add sparkle to our holidays. Year-round, scientists funded by the National Institutes of Health use light to illuminate important biological processes, from the inner workings of cells to the complex activity of the brain. Here’s a look at just a few of the ways new light-based tools have deepened our understanding of living systems and set the stage for future medical advances. A new fluorescent probe shows viral RNA (red) in an RSV-infected cell. Credit: Eric Alonas and Philip Santangelo, Georgia Institute of Technology and Emory University. Visualizing Viral Activity...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 29, 2014 Category: Research Authors: Srivalli Subbaramaiah Tags: Cell Biology Cool Images Source Type: blogs

Profit over Safety – Centers for Disease Control Names 271 New Vaccinations
Conclusion How many vaccinations will be considered to be a sensible number? If all of the vaccinations currently under development are deemed a success, how many of them will be added to the schedule? As there is little research to determine which ingredients are in the vaccinations listed as “under development” by the CDC, many parents are concerned about their toxicity and how best to protect their children. I will leave you with the wise words of Robert F, Kennedy Jr: “Vaccine industry money has neutralized virtually all of the checks and balances that once stood between a rapacious pharmaceutical industry and ou...
Source: vactruth.com - August 3, 2015 Category: Allergy & Immunology Authors: Christina England Tags: Christina England Logical Top Stories Centers for Disease Control (CDC) PhRMA Robert F. Kennedy Jr. World Health Organization (WHO) Source Type: blogs

Why Doctors should read books by Nassim Taleb
By SAURABH JHA, MD     “There are some enterprises in which a careful disorderliness is the true method” Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathem...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

Why Doctors (And Everybody Else) Should Read Books by Nassim Taleb
By SAURABH JHA, MD “There are some enterprises in which a careful disorderliness is the true method” – Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathematicia...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

The Luxury to Choose
By TRAVIS BIAS, MD The 80 year-old woman lay on her mat, her legs powerless, looking up at the small group that had come to visit her. There were no more treatment options left. The oral liquid morphine we had brought in the small plastic bottle had blunted her pain. But, she would be dead in the coming days. The cervical cancer that was slowly taking her life is a notoriously horrible disease if left undetected and untreated and that is exactly what had happened in this case. We had traveled hours by van along dirt roads to this village with a team of health workers from Hospice Africa Uganda, the country’s authority o...
Source: The Health Care Blog - February 25, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Gardasil Hospice Africa Uganda vaccines Source Type: blogs

No Treatment or Vaccine for Ebola, but a $1000 Pill for Hepatitis C
The Ebola virus epidemic in West Africa continues to grow, and now appears to be the worst known epidemic of that disease to date.  In the US and Western Europe, press reports are now raising concerns that the disease could spread there.  For example, CNN, in an article entitled "Ebola Fears Hits Close to Home," was a section headed "Could Ebola spread to the US?" An ABC article was entitled, "How the US Government Could Evacuate Americans with Ebola."Reasons for fear of spread are the increased mobility of people made possible by air travel, and the lack of specificity of early symptoms of Ebola, so infectious p...
Source: Health Care Renewal - July 31, 2014 Category: Health Management Tags: Ebola virus economism hepatitis C neoliberalism pharmaceuticals Sovaldi Source Type: blogs

Health Cooperation In The New U.S.-Cuban Relationship
Four months after the surprise announcement of his determination to normalize relations with Cuba, President Barack Obama is rapidly translating that wish into reality, with the cooperation of Cuban counterparts and widespread support among Americans. On April 11, the Summit of the Americas featured the first meeting of the two countries’ presidents in over fifty years. Three days later, even amidst a struggle with Congress over a possible nuclear deal with Iran, the Obama administration announced it will remove Cuba from the U.S. list of state sponsors of terrorism, a step Carl Meacham, Director of the Center for Strate...
Source: Health Affairs Blog - April 29, 2015 Category: Health Management Authors: J. Stephen Morrison Tags: Featured Global Health Bill Frist Cuba cuban health care Raúl Castro U.S.-Cuban relationship Source Type: blogs

The Law of Diminishing Returns of Ethicism
SAURABH JHA MD Many allege that the FIRST trial, which randomized surgical residencies to strict versus flexible adherence to duty hour restrictions, was unethical because patients weren’t consented for the trial and, as this was an experiment, in the true sense of the word, consent was mandatory. The objection is best summarized by an epizeuxis in a Tweet from Alice Dreger, a writer, medical historian, and a courageous and tireless defender of intellectual freedom. @RogueRad @LVSelbs @ethanjweiss @Skepticscalpel Consent to experimentation. Consent. Consent. Am I not being clear? — Alice Dreger (@AliceDreger) Nov...
Source: The Health Care Blog - March 20, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Uncategorized Source Type: blogs