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Total 33 results found since Jan 2013.

A man in his 70s with weakness and syncope
DiscussionBrugada Type 1 ECG changes are associated with sudden cardiac death (SCD) and the occurrence of ventricular dysrhythmias. Patients that develop a Type 1 pattern without any precipitating or provoking factors have a risk of SCD of 0.5-0.8% per year. In patients that only have this pattern induced by a sodium channel blocking agent have a lower rate of SCD (0 - 0.35% per year)[1]. Drugs that have been associated with Brugada ECG patterns include tricyclic antidepressants, anesthetics, cocaine, methadone, antihistamines, electrolyte derangements, and even tramadol. [2]. Our patient had a Brugada Type ...
Source: Dr. Smith's ECG Blog - July 22, 2023 Category: Cardiology Authors: Pendell Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A big data COVID train wreck
BY ANISH KOKA If there was any doubt the academic research enterprise is completely broken, we have an absolute train wreck of a study in one of the many specialty journals of the Journal of the American Medical Association — JAMA Health. I had no idea the journal even existed until today, but I now know to approach the words printed in this journal to the words printed in supermarket tabloids. You should too! The paper that was brought to my attention is one that purports to examine the deleterious health effects of Long COVID. A sizable group of intellectuals who are still socially distancing and wearing n95s ...
Source: The Health Care Blog - March 13, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy Anish Koka Covid research COVID-19 Long Covid Source Type: blogs

Myocarditis update from Sweden
BY ANISH KOKA The COVID19/vaccine myocarditis debate continues in large part because our public health institutions are grossly mischaracterizing the risks and benefits of vaccines to young people. A snapshot of what the establishment says as it relates to the particular area of concern: college vaccine mandates: Dr. Arthur Reingold, an epidemiology professor at UC-Berkeley, notes that UC also requires immunizations for measles and chickenpox, and people still are dying from COVID at rates that exceed those for influenza. As of Feb. 1, there were more than 400 COVID deaths a day across the U.S. “The arg...
Source: The Health Care Blog - February 27, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Anish Koka covid19 myocarditis Sweden Source Type: blogs

60 year old with vomiting, diarrhea, and syncope: is this Wellens? Is this type 2 MI?
 Written by Jesse McLaren, with edits/comments by Smith and Grauer A 60 year-old patient with diabetes and ESRD presented with 24 hours of vomiting, diarrhea, weakness and then a syncopal episode. Vitals: RR 18, sat 98%, HR 103, BP 124/71 and temp 38.0. Here ’s their ECG: is this Wellens?  There ’s borderline sinus tach, normal conduction, normal axis, and low voltages in the limb leads. The anterior leads have loss of R waves, mild convex ST segments and primary T wave inversion. In the context of QS waves, T wave inversion indicates old or subacute infarct, or reperfusion after signif icant infarc...
Source: Dr. Smith's ECG Blog - August 19, 2022 Category: Cardiology Authors: Jesse McLaren Source Type: blogs

Vaccine associated myocarditis revisited with COVID-19 mRNA vaccines
When I had reviewed the topic of vaccine associated myocarditis for an editorial in the BMH Medical Journal in 2017, most of the cases were associated with small pox vaccination [1]. There were also reports of streptococcal pneumonia vaccine and influenza vaccine associated myocarditis. Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) used in the vaccine were also implicated in some cases [2,3]. While the large scale vaccination for small pox in an attempt to prepare for potential bioterrorism was the association in 2003 [4], COVID-19 mRNA vaccines are currently in the limelight for vaccine induced myocarditis...
Source: Cardiophile MD - July 22, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Sweat Sensor Warns of Impending COVID-19 Cytokine Storm
Researchers at the University of Texas and EnLiSense, a Texas startup, have developed a skin sweat sensor that can measure cytokine levels continuously for up to 168 hours. The technology has been adapted so that it can detect cytokines involved in t...
Source: Medgadget - April 16, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Critical Care Medicine Public Health Source Type: blogs

3 simple steps to jump-start your heart health this year
In 2020, the terrible toll of the COVID-19 pandemic largely overshadowed the affliction that remains the leading cause of death in this country: heart disease. In the United States last year, at least twice as many people died from cardiovascular causes as those who died from complications from SARS-CoV-2, the novel coronavirus. While the challenges from the virus are new, experts have been studying heart disease for decades — and everyone can benefit from that knowledge. “The lifestyle habits that keep your heart healthy may also leave you less vulnerable to serious complications from infections such as COVID-19 and i...
Source: Harvard Health Blog - January 12, 2021 Category: Consumer Health News Authors: Julie Corliss Tags: Exercise and Fitness Health Healthy Eating Heart Health Source Type: blogs

ECMO – Extracorporeal membrane oxygenation
ECMO – extracorporeal membrane oxygenation ECMO – Extracorporeal membrane oxygenation – has been in use for the past four decades to support persons who are unlikely to survive with mechanical ventilation. ECMO is used in both adult and pediatric practice, though in the initial years, use of ECMO was restricted to pediatric intensive care. The enthusiasm for use of ECMO in adults have been triggered by the beneficial effect noted during the last H1N1 influenza pandemic [1]. In contrast from cardiopulmonary bypass which is used for a short period during cardiac surgery, ECMO is used to support for a ...
Source: Cardiophile MD - December 26, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiac Surgery Source Type: blogs

Viruses on Motorcycles
By ANISH KOKA The most recent fiction dressed up as science about COVID comes to us courtesy of a viral Washington Post article.  “How the Sturgis Motorcycle Rally may have spread coronavirus across the Upper Midwest” screams the headline.   The charge made is that “within weeks” of the gathering that drew nearly half a million visitors the Dakota’s and adjacent states are experiencing a surge of COVID cases.   The Sturgis Rally happens to be a popular motorcycle rally held in Sturgis, South Dakota every August that created much consternation this year because it wasn’t cancel...
Source: The Health Care Blog - October 26, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy Anish Koka Pandemic sturgis motorcycle rally Source Type: blogs

Sotalol – class IIIa
Sotalol is a class IIIa antiarrhythmic agent as per the Modernized Classification of Cardiac Antiarrhythmic Drugs [1]. The class effect is voltage dependent K+ channel blocker. Specifically, it is a HERG channel –mediated rapid K+ current (IKr) blocker. It has additional action on beta 1 and beta 2 receptors. Sotalol increases refractory period and decreases tendency for reentry. The drug is useful in ventricular tachycardia without structural heart disease and in those with a remote myocardial infarction. It is also useful in atrial fibrillation with conduction through accessory pathway in WPW syndrome. ...
Source: Cardiophile MD - October 15, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: ECG / Electrophysiology Source Type: blogs

What Can We Expect From 2021: The COVID Perspective
Nearing the end of 2020, we are globally far from seeing the end of the pandemic that ruled (and ruined) 2020. Every day we see hundreds of thousands of new cases of coronavirus infections, with the WHO reporting a record one-day rise, while people have a hard time complying with the strict safety measures again. We are all waiting for this nightmare to stop, but will it ever? How long, ‘till we need to keep masks on and stay away from grandma? After this dystopian 2020, how are we looking at 2021? No one knows for sure. With countries being knee-deep in the second wave, everyone is waiting for the vaccines to put an ...
Source: The Medical Futurist - October 15, 2020 Category: Information Technology Authors: Judit Kuszkó Tags: Forecast Digital Health Research Future of Medicine Science Fiction fake news vaccination covid covid19 pandemic vaccine hoax flu Oxfam COVAX olympics Source Type: blogs

Role of RT-PCR in the diagnosis of Rheumatic fever/RHD
RT-PCR: Real-time polymerase chain reaction, a sophisticated gene sequence-based biochemical test. Thanks to corona, this complex medical investigation has become a household name. Jones proposed his criteria to diagnose acute rheumatic fever  in 1944, we still use it to diagnose with many modifications . Currently, AHA position statement – 2015 by Gewitz et all is  being followed. (Circulation 2015) From Braunwald textbook of cardiology. Apart from this, there is one catch . Even if the child fulfills Jone criteria, there needs to be evidence for preceding streptococcal sore throat, either by culture or antibody. ...
Source: Dr.S.Venkatesan MD - October 1, 2020 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized acute rheumatic fever aha rhd 2015 rhuematic fever anti dnase streptococcus group a beta hemolytic streptococci rtpcr mirna rtpcr rhd qpcr in rheumatic fever revised jonec criteria 2015 RHD jones criteria role of rtpcr fro Source Type: blogs

COVID herd immunity: At hand or forever elusive?
By MICHEL ACCAD, MD With cases of COVID-19 either disappeared or rapidly diminishing from places like Wuhan, Italy, New York, and Sweden, many voices are speculating that herd immunity may have been reached in those areas and that it may be at hand in the remaining parts of the world that are still struggling with the pandemic.  Lockdowns should end—or may not have been needed to begin with, they conclude. Adding plausibility to their speculation is the discovery of biological evidence suggesting that prior exposure to other coronaviruses may confer some degree of immunity against SARS-CoV2, a...
Source: The Health Care Blog - July 30, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy immunity MICHEL ACCAD Pandemic Source Type: blogs

COVID-19: Physicians in Shackles
By ANISH KOKA, MD A number of politically tinged narratives have divided physicians during the pandemic. It would be unfortunate if politics obscured the major problem brought into stark relief by the pandemic: a system that marginalizes physicians and strips them of agency. In practices big and small, hospital-employed or private practice, nursing homes or hospitals, there are serious issues raising their heads for doctors and their patients. No masks for you When I walked into my office Thursday, March 12th, I assembled the office staff for the first time to talk about COVID.  The prior weekend had been awa...
Source: The Health Care Blog - May 2, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Physicians Anish Koka medical autonomy Pandemic Source Type: blogs