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Total 56 results found since Jan 2013.

A woman in her 20s with syncope
Written by Destiny Folk MD, with edits by Meyers, peer reviewed by Smith and GrauerA woman in her late 20s with a past medical history of cervical cancer status post chemotherapy and radiation therapy presented to the emergency department for shortness of breath, chest tightness, and two episodes of syncope.Her initial vital signs revealed a temp of 97.7F, HR 125, RR 20, BP 115/90, and an oxygen saturation of 95% on room air. Upon arrival, she did not appear in acute distress. She was noted to be tachycardic and her heart sounds were distant on physical exam. She had a normal respiratory effort, and her lungs were clear to...
Source: Dr. Smith's ECG Blog - November 28, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

Which chemotherapeutic agent is well known to cause coronary vasospasm?
5-fluorouracil is well known to cause coronary vasospasm. 5-fluorouracil and its orally active prodrug capecitabine are fluoropyrimidines, belonging to the class of antimetabolites used for treatment of malignancies of breast, head and neck tumours and gastrointestinal tumours. Mechanisms for coronary vasospasm Endothelial cell damage with cytolysis and denudation Increased endothelin-1 bioactivity leading to vasoconstriction When high dose infusions are given, coronary vasospasm with angina, arrhythmia or even sudden death can occur in up to 5% of patients. Vascular toxicity occurs generally within 72 hours of the...
Source: Cardiophile MD - November 13, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

What is pericardial effusion – Cardiology Basics
What is pericardial effusion – Cardiology Basics Pericardial effusion is collection of fluid between the visceral and parietal layers of the pericardium. If the amount of pericardial fluid is large or there is a rapid increase in the amount of pericardial fluid, compression of the heart prevents its proper filling. This reduces cardiac output and causes hypotension and is known as cardiac tamponade. Cardiac tamponade needs urgent pericardial aspiration or surgical drainage if the fluid is very thick. Very thick fluid can be there in purulent bacterial pericarditis. Sometimes it can be a hemopericardium due to bleedin...
Source: Cardiophile MD - October 24, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Weekly Overseas Health IT Links –24th September, 2022.
This article makes the case and explains what will be required to make it happen.We hear a lot about “digital health” these days. As data about our health piles up — thanks to sources like electronic health records, personal fitness apps and gadgets, and home genome test kits — weshould understand a lot more than we used to about what ’s wrong with our health and what to do about it. But having a lot of data is not enough. We have to be aware of what we have, understand what it means, and act on that understanding. While the challenges are in some ways more acute in the United States because of its fragmented sys...
Source: Australian Health Information Technology - September 24, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

A woman in her 60s with syncope and vomiting. Does she need a pacemaker?
 Written by Pendell Meyers with some edits by Steve SmithA woman in her 60s on chemotherapy presented to the Emergency Department for a syncopal episode just prior to arrival. She was walking to the bathroom when she suddenly felt nauseous and passed out. EMS was called by the patient ' s daughter, and en route to the ED she vomited twice. On arrival to the ED, she adamantly denies chest pain but says she ' s " just still not feeling well. " She had no prior known cardiac disease.Triage at 0755:The rhythm is most either atrial fibrillation with complete heart block and resulting junctional escape, or atrial flutter wi...
Source: Dr. Smith's ECG Blog - November 19, 2021 Category: Cardiology Authors: Pendell Source Type: blogs

Fight Aging! Newsletter, April 12th 2021
In conclusion, the MR exhibited the protective effects against age-related behavioral disorders, which could be partly explained by activating circulating FGF21 and promoting mitochondrial biogenesis, and consequently suppressing the neuroinflammation and oxidative damages. These results demonstrate that FGF21 can be used as a potential nutritional factor in dietary restriction-based strategies for improving cognition associated with neurodegeneration disorders. Senescent T Cells Cause Changes in Fat Tissue that are Harmful to Long-Term Health https://www.fightaging.org/archives/2021/04/senescent-t-cells-cause-...
Source: Fight Aging! - April 11, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Phenocopies of hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is characterized by hypertrophy of the left ventricle, not related to load. It is a genetically transmitted condition. There are several mimickers of hypertrophic cardiomyopathy which can be called phenocopies of hypertrophic cardiomyopathy. Conventional form of HCM has been called sarcomeric HCM as it is due to mutations in genes encoding sarcomeric proteins [1]. Here is a small list of phenocopies of hypertrophic cardiomyopathy which is not truly exhaustive: Fabry disease Danon disease PRKAG2 Cardiomyopathy Pompe disease Cardiac amyloidosis Athlete’s heart Hypertensive heart disease ...
Source: Cardiophile MD - February 24, 2021 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Mimickers of HCM Mimickers of hypertrophic cardiomyopathy Mimics of HCM Mimics of hypertrophic cardiomyopathy Source Type: blogs

Cardiovascular risk in cancer survivors
Improvements in cancer care has its impact on better survival of those with early stage disease in several malignancies. In this scenario, cardiovascular disease has become a competing cause of death. It is not just due to chemotherapy induced myocardial disease, but also due to common risk factors for cardiovascular disease in this population. Hypertension, cigarette smoking and loss of cardiovascular fitness are some of them [1]. Weight gain may be also a problem in some. Those who have survived cancer for over 5 years have a 1.3 to 3.6 fold increased risk of cardiovascular mortality. Increased incidence of cardiovascu...
Source: Cardiophile MD - May 21, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Still Negative on Watchman
Many readers have contacted me to ask whether my negative viewson left atrial appendage occlusion with Watchman have changed since 2017.   The short answer is no. My views are even more negative today.  In 2016, I published an editorial on theHeart.org | Medscape Cardiology arguing that this procedure should stop. One of the rebuttals was that it was a blog post, not an academic editorial. Months later, Andrew Foy, Gerald Naccarelli and I put the same argument into academic-speak and the influential journal Heart Rhythm published it.[1] I have debated and presented this topic multiple times ...
Source: Dr John M - May 17, 2019 Category: Cardiology Authors: Dr John Source Type: blogs

Chemotherapeutic agent causing coronary vasospasm – Cardiology MCQ – Answer
Chemotherapeutic agent causing coronary vasospasm – Cardiology MCQ – Answer Chemotherapeutic agent well known to cause coronary vasospasm:Correct answer: c) 5-fluorouracil 5-fluorouracil and its orally active prodrug capecitabine are fluoropyrimidines, belonging to the class of antimetabolites used for treatment of malignancies of breast, head and neck tumours and gastrointestinal tumours. Mechanisms for coronary vasospasm Endothelial cell damage with cytolysis and denudation Increased endothelin-1 bioactivity leading to vasoconstriction When high dose infusions are given, coronary vasospasm with angina, arrh...
Source: Cardiophile MD - February 22, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Medication to prevent anthracycline cardiotoxicity – Cardiology MCQ – Answer
Medication to prevent anthracycline cardiotoxicity – Cardiology MCQ – Answer Medication which is universally recommended to prevent anthracycline cardiotoxicity when high dose cancer chemotherapy is planned: Correct answer: 2. Dexrazoxane Dexrazoxane has been used intravenously to protect the heart against chemotherapeutic agents like doxorubicin. US Food and Drug Administration has approved its use only in adult patients as there was a possible risk of secondary malignancy in pediatric patients. It is a derivative of EDTA and chelates iron so that less number is available to bind with anthracyclines and form ...
Source: Cardiophile MD - December 8, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

Medication to prevent anthracycline cardiotoxicity – Cardiology MCQ
Medication to prevent anthracycline cardiotoxicity – Cardiology MCQ Medication which is universally recommended to prevent anthracycline cardiotoxicity when high dose cancer chemotherapy is planned: Dexamethasone Dexrazoxane Deflazacort None of the above Post your answer as a comment below The post Medication to prevent anthracycline cardiotoxicity – Cardiology MCQ appeared first on All About Cardiovascular System and Disorders.
Source: Cardiophile MD - December 6, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

When will the stigma of mental health end in medicine?
Imagine being a cancer patient afraid of seeing an oncologist because they would likely need to discuss chemotherapy and all the lifestyle changes that it entails. Imagine being a patient with heart failure afraid of seeing the cardiologist because they may be prescribed a diuretic to remove excess fluid from their body and may need […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - November 15, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/anonymous" rel="tag" > Anonymous < /a > Tags: Physician Psychiatry Source Type: blogs

Guidelines, multiple specialists, and the science versus the art of medicine
My 80-year-old patient presented with symptoms and signs of kidney failure. I hospitalized him and asked for the assistance of a kidney specialist. We notified his heart specialist as a courtesy. A complicated evaluation led to a diagnosis of an unusual vasculitis with the patient’s immune system attacking his kidney as if it was a foreign toxic invader. Treatment, post kidney biopsy, involved administering large doses of corticosteroids followed by a chemotherapy agent called Cytoxan. Six days later it was clear that dialysis was required at least until the patient’s kidneys responded to the therapy and began working ...
Source: Kevin, M.D. - Medical Weblog - July 16, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/steven-reznick" rel="tag" > Steven Reznick, MD < /a > Tags: Physician Cardiology Hospital-Based Medicine Source Type: blogs

If Breast Cancer Doesn ' t Kill You, Heart Failure Might
File this in the category of the stuff we should have been told but weren ' t. Many women diagnosed with breast cancer, are given chemotherapy as part of their treatment. One of the drugs commonly used is calledDoxorubicin, also known Adriamycin or Rubex, or as us patients have been known to call it ' red devil ' , which carries a significant cardiac risk.When you are given it in chemo the nurses put on masks and special gowns to protect them. No thought of the patients. I was told it could cause some cardiac issues but now I am learning that the danger is very real and very concerning." “Both breast cancer and cardiovas...
Source: Caroline's Breast Cancer Blog - February 2, 2018 Category: Cancer & Oncology Tags: breast cancer treatment cardiac chemotherapy Source Type: blogs