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Focus on for new Rx class for inflamed disorders discovered
Research led by Charles Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Middle New Orleans, describes a powerful new anti-inflammatory mechanism that could lead to the introduction of new oral medications for atherosclerosis and inflammatory bowel disorders (IBS). The findings are published in PLOS ONE . Among the master inflammatory molecules in the body is usually Tumor Necrosis Factor-alpha (TNF-alpha). Bacterial infections and certain diseases lead to the production of this molecule, which then stimulates an immune response. Diseases like atherosclerosis, rheumatoid arthritis, and IBS are ...
Source: My Irritable Bowel Syndrome Story - October 3, 2013 Category: Other Conditions Authors: Ken Tags: IBS News Source Type: blogs

Health Datapalooza 2017 Day 1: Data Liberation, Sharing, and Analytics
Welcome to Medgadget‘s coverage of Health Datapalooza 2017, an AcademyHealth event, in Washington, DC. The now annual event was launched in 2010 by the Obama administration as a hackathon-style program where attendees were challenged to deve...
Source: Medgadget - May 1, 2017 Category: Medical Equipment Authors: Michael Batista Tags: Exclusive Source Type: blogs

Hepatitis C
is a recently discovered disease. Harvey J. Alter identified the variant form of Hepatitis during the 70s, which then became known as a ‘non-A, non-B Hepatitis (NANBH)’. In the 1980s, Michael Houghton and his team isolated the genome of the new virus, and it was named ‘Hepatitis C’. Finally, in 1997 Charles M. Rice proved that the virus is a disease agent, capable of acting alone to cause Hepatitis. This year’s Nobel Prize in Medicine has been jointly awarded to Harvey J. Alter, Michael Houghton, and Charles M. Rice for the discovery of the virus. Their contributions (illustrated below) have led to improved unde...
Source: GIDEON blog - November 10, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Source Type: blogs

Physician Payment Sunshine: ProPublica Database Leads with Disparaging Headlines
Doctor collaborates with industry to conduct lifesaving, breakthrough research.”  “Doctor educates colleagues about safety and clinical date to improve patient outcomes.”  “Physician speaks to peers about new trials that improve patient access to needed drugs.”  “Researchers meet to ensure the success of new clinical trial.”    “Physician invents new medical device that improves cardiovascular health.”  “Industry and physicians collaborate to bring drug to market faster through new approval pathway.”  “Physicians attend education program mandated by FDA under REMS to better understand benef...
Source: Policy and Medicine - April 3, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs

Maybe It Really Is Different This Time For Patients With Advanced Melanoma
Every convention and large meeting has a theme, and at the annual meeting of the American Society of Clinical Oncology in Chicago the theme is "Building Bridges To Conquer Cancer." But for me, the theme as articulated in my blog the other day is "Is it really different this time?" Some agree with me and some don't, but that's OK. I am wearing a badge that says I am a "35 year member of ASCO" (I actually have been attending these meetings longer than that) so I perhaps have a bit of a different perspective than those younger than me. And there is plenty of commentary to back up my well-meaning and hopefully thought provokin...
Source: Dr. Len's Cancer Blog - June 3, 2013 Category: Cancer Authors: Dr. Len Tags: Cancer Care Medications Other cancers Research Survivors Treatment Vaccines Source Type: blogs

Has pancreatic damage from glucagon suppressing diabetes drugs been underplayed? - BMJ
BMJ 2013; 346 doi: http://dx.doi.org/10.1136/bmj.f3680 (Published 10 June 2013) Cite this as: BMJ 2013;346:f3680Article Related content Article metrics Deborah Cohen, investigations editor Author Affiliations dcohen@bmj.com Incretin mimetics have been called “the darlings of diabetes treatment” and they may soon also be licensed for treating obesity. But a BMJ investigation has found growing safety concerns linked to the drugs’ mechanism of action. Deborah Cohenasks why patients and doctors have not been told. They’ve been touted as th...
Source: PharmaGossip - June 11, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs

Voices for Vaccines: 11 Facts Show How it’s a Propaganda Ploy for Emory University, CDC, and Big Pharma
Conclusion The Voices for Vaccines program at the Task Force for Global Health may be administered by a few mothers, but they are not the ones pulling the strings behind the scenes. The information in this article reveals who keeps the lights on for the website and the Task Force organization as a whole. Furthermore, the past, present and future relationships with the Centers for Disease Control, Emory University, and pharmaceutical companies should immediately raise a red flag for any parent. Especially when the message calls for you to blindly trust doctors injecting dangerous chemicals into your child. If you want to ta...
Source: vactruth.com - February 19, 2014 Category: Health Medicine and Bioethics Commentators Authors: Jeffry John Aufderheide Tags: Jeffry John Aufderheide Top Stories Alan Hinman Deborah Wexler Emory University Paul Offit Stanley Plotkin Task Force for Global Health U.S. Centers for Disease Control and Prevention Voices for Vaccines Source Type: blogs

The 1000th Thread!
This is the 1000th presentation to my bioethics blog since starting on Google Blogspot.com in 2004.There has been many topics covered. Though comments by the visitors has always been encouraged and, since as a " discussion blog " , comments leading to discussions I have felt was the definitive function here. Virtually none of the thread topics have gone unread and most have had some commentary, some with mainly particularly strong and emphatic opinions http://bioethicsdiscussion.blogspot.com/2013/01/should-pathologists-be-physicians.html, some with extensive up to 12 years long continued discussion http://bioethicsdiscussi...
Source: Bioethics Discussion Blog - December 24, 2017 Category: Medical Ethics Source Type: blogs

Fight Aging! Newsletter, May 27th 2019
In this study, we found that cofilin competes with tau for direct microtubule binding in vitro, in cells, and in vivo, which inhibits tau-induced microtubule assembly. Genetic reduction of cofilin mitigates tauopathy and synaptic defects in Tau-P301S mice and movement deficits in tau transgenic C. elegans. The pathogenic effects of cofilin are selectively mediated by activated cofilin, as active but not inactive cofilin selectively interacts with tubulin, destabilizes microtubules, and promotes tauopathy. These results therefore indicate that activated cofilin plays an essential intermediary role in neurotoxic signaling th...
Source: Fight Aging! - May 26, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Weekly Australian Health IT Links – 22 August, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----This week we seem to have more in the way of State-Based initiatives as well as the usual rubbish info sessions from the ADHA.Also the usual from of NBN news and news of #myHR Rule 42 – which I had never heard of!-----https://www.australianageingagenda.com.au/contributors/opinion/critical-staff-shortages-affect-more-than-frontli...
Source: Australian Health Information Technology - August 22, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Weekly Overseas Health IT Links – 15th October, 2022.
This article uses the one that divides providers into groups depending on the life cycle stage the clinic is at the given moment. According to this classification, medical providers fall into three groups:BeginnersGrowing clinicsWell-established providersHealth care providers are business entities, so their life cycle, like that of any business, consists of the early stage or launch, growth and maturity. At each stage, providers have different priorities and goals, and the choice of medical software solutions should be made accordingly.Medical software for beginnersThe launch phase can be tough. At this stage, the profits ...
Source: Australian Health Information Technology - October 15, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation. Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/ Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred year...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs