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Complex regional pain syndrome-An interdisciplinary view from the surgical consultation
Chirurg. 2021 Nov 8. doi: 10.1007/s00104-021-01529-z. Online ahead of print.ABSTRACTChronic pain disorders are common and have a substantial impact on the patients' daily life. The specific syndrome of complex regional pain syndrome (CRPS, Sudeck's disease) is comparatively rare and characterized by additional sensorimotor, vascular and trophic dysfunctions. The diagnosis is made based on the Budapest criteria and according to clinical symptoms. According to the German national guidelines, multimodal therapy includes drug, rehabilitative and psychosomatic approaches for the reduction of pain and restoration of functionalit...
Source: Der Chirurg - November 8, 2021 Category: Surgery Authors: Nils Becker Alexander Deilmann Pascal Kowark Frank Hildebrand Philipp Lichte Source Type: research

Altered regulation of the T-cell system in patients with CRPS
AbstractThe aim of this study was to investigate T-cell subsets and immunomodulatory factors in patients with complex regional pain syndrome (CRPS). We found decreased numbers of pro-inflammatory Th17 cells in patients with CRPS as compared to healthy volunteers. The expression of Th17 related ROR γT mRNA was also significantly decreased. Patients with CRPS showed an increased proportion of CD39+ Tregs. CD39 is a known inhibitor of Th17 cell differentiation. Systemic cytokine levels were almost unchanged in patients with CRPS. These findings suggest that the decrease in Th17 cells in CRPS is regulated by an increase in CD...
Source: Inflammation Research - August 28, 2018 Category: Research Source Type: research

The German version of the Bath Body Perception Disturbance Scale (BBPDS-D) : Translation, cultural adaptation and linguistic validation on patients with complex regional pain syndrome.
CONCLUSION: This German translation and cross-cultural adaptation of the original English version of the BBPDS is a valid instrument to assess body perception disturbances in German speaking CRPS patients. Future research should further assess the impact of body perception disturbance on treatment outcome and prognosis. PMID: 29736619 [PubMed - as supplied by publisher]
Source: Schmerz - May 7, 2018 Category: Anesthesiology Authors: Tschopp M, Swanenburg J, Wertli MW, Langenfeld A, McCabe CS, Lewis J, Baertschi E, Brunner F Tags: Schmerz Source Type: research