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Total 31 results found since Jan 2013.
Newly Repopulated Spinal Cord Microglia Exhibit A Unique Transcriptome And Coincide With Sex-Independent Pain Resolution
The transition from acute-to-chronic pain is important because underlying mechanisms may reveal targets for the treatment of chronic pain. Spinal cord microglial activation results from persistent neuronal hyperexcitability, and this can trigger feedforward synaptic plasticity that contributes to chronic pain. We used a targeted, inducible genetic microglial depletion strategy in the clinically relevant tibial fracture/casting model of complex regional pain syndrome (CRPS) to interrogate the contribution of microglia to pain progression.
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: Caldwell M. Bridges, Lauren J. Donovan, Amy R. Nippert, Meng Wang, Shaogen Wu, Thomas E. Forman, Elena S. Haight, Nolan A. Huck, Claire E. Jordan, Aysha S. Gardner, Ramesh V. Nair, Vivianne L. Tawfik Source Type: research
Distress and resilience narratives within pain memories of adolescents and young adults with complex regional pain syndrome: A multi-method study
Complex regional pain syndrome (CRPS) is a persistent, localized chronic pain condition that typically affects the extremities (57). Prevalence of CRPS in pediatric populations is estimated at 1.16/1000, with higher rates in females and peak onset during adolescence (1). As a primary pain condition, young people with CRPS report significantly elevated levels of pain compared to young people with other conditions including chronic back or abdominal pain (32). Previous literature has focused on examining pain-related disability and functioning in chronic pain more broadly (48) and also in relation to CRPS (50,52), while rece...
Source: The Journal of Pain - March 1, 2023 Category: Materials Science Authors: Emy Nimbley, Line Caes, Melanie Noel, Abbie Jordan Tags: Original Reports Source Type: research
Combining Stellate ganglion block and intravenous regional anesthesia to treat complex regional pain syndrome: A 19-years' experience in a tertiary center
CONCLUSION: We find it practical, inexpensive, safe, and straightforward to combine SGB with IVRA for CRPS patients.PMID:36261198 | DOI:10.15537/smj.2022.43.10.20220318
Source: Saudi Medical Journal - October 19, 2022 Category: Middle East Health Authors: Abdelkarim S Aloweidi Sami A Abu Halaweh Mahmoud M Al-Mustafa Islam M Massad Ibraheem Y Qudaisat Aws M Khanfar Jihad M Ajlouni Shaher T Alhadidi Ahmad I El-Share Mohammad A Jarbeh Anas A Al-Oweidi Source Type: research
