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Our 15-year experience of complications of Chow's technique for endoscopic carpal tunnel releasing
CONCLUSIONS: Our study revealed that ECTR could reduce structural and cutaneous complications, but increase the incidence of nerve injury. we speculated that the incidence of CRPS I may be higher in the Asian population.PMID:35262469 | DOI:10.1080/01616412.2022.2051134
Source: Neurological Research - March 9, 2022 Category: Neurology Authors: Yu-Xuan Wu He Yin Jia-Yi Lin Hua-Jun Jiang Feng Han Si-da Liu Wei Qu Source Type: research

Effectiveness of perampanel in managing chronic pain caused by the complex regional pain syndrome: A case report
This report describes a patient with complex regional pain syndrome (CRPS) type I in the right lower leg and foot who responded well to perampanel, an AMPA receptor antagonist, for managing the chronic pain. Patient concern: A 61-year-old woman complained of pain in her right lower leg and foot over a period of 7 year (numeric rating scale: 8) due to CRPS type I. Diagnosis: CRPS type 1. Interventions: Despite the combination of 300 mg pregabalin, 225 mg/1950 mg tramadol/acetaminophen, and 10 mg nortriptyline per day, her right lower leg and foot were nearly disabled due to the severity of the p...
Source: Medicine - December 3, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Involvement of nuclear factor κB and descending pain pathways in the anti-hyperalgesic effect of β-citronellol, a food ingredient, complexed in β-cyclodextrin in a model of Complex Regional Pain Syndrome - Type 1
Food Chem Toxicol. 2021 May 26:112260. doi: 10.1016/j.fct.2021.112260. Online ahead of print.ABSTRACTComplex regional pain syndrome type 1 (CRPS-1) is a painful syndrome without effective treatment. In order to explore possible new treatments, we used an animal model of CRPS-1 to examine the effects of β-Citronellol (βCT), a monoterpene found in a variety of plants that has been shown to have analgesic effects. We aimed to assess its effects alone, and complexed with β-cyclodextrin (βCD), which has been previously used to enhance the effects of a number of medicines. The βCT-βCD was characterized physiochemically usi...
Source: Food and Chemical Toxicology - May 29, 2021 Category: Food Science Authors: Priscila L Santos Thallita K Rabelo Jo ão P S C F Matos Kl écia S Anjos Marlange A O Melo Yasmim M B G Carvalho Bruno S Lima Paula P Menezes Adriano A S Ara újo Laurent Picot Jackson R G S Almeida Renan G Brito Lucindo J Quintans-J únior Source Type: research

Antiepileptic drugs for chronic non-cancer pain in children and adolescents.
CONCLUSIONS: This review identified only two small studies, with insufficient data for analysis.As we could undertake no meta-analysis, we were unable to comment about efficacy or harm from the use of antiepileptic drugs to treat chronic non-cancer pain in children and adolescents. Similarly, we could not comment on our remaining secondary outcomes: Carer Global Impression of Change; requirement for rescue analgesia; sleep duration and quality; acceptability of treatment; physical functioning; and quality of life.We know from adult randomised controlled trials that some antiepileptics, such as gabapentin and pregabalin, ca...
Source: Cochrane Database of Systematic Reviews - August 5, 2017 Category: General Medicine Authors: Cooper TE, Wiffen PJ, Heathcote LC, Clinch J, Howard R, Krane E, Lord SM, Sethna N, Schechter N, Wood C Tags: Cochrane Database Syst Rev Source Type: research

Complex regional pain syndrome type I. An analysis of 7 cases in children
Conclusions CRPS is frequently unrecognised in children, leading to family anxiety and unnecessary para-clinical costs. Paediatricians and paediatric neurologists should be aware of this syndrome in order to avoid delay in diagnosis, unnecessary studies, and multiple visits to specialists, with a view to providing effective treatment.
Source: Neurologia - June 13, 2015 Category: Neurology Source Type: research

Topical combinations to treat microvascular dysfunction of chronic postischemia pain.
CONCLUSIONS: The present results support the hypothesis that allodynia in an animal model of CRPS is effectively relieved by topical combinations of α2A receptor agonists or NO donors with PA or PDE inhibitors. This suggests that topical treatments aimed at improving microvascular function by increasing both arterial and capillary blood flow produce effective analgesia for CRPS. PMID: 24651238 [PubMed - in process]
Source: Anesthesia and Analgesia - March 22, 2014 Category: Anesthesiology Authors: Laferrière A, Abaji R, Tsai CY, Ragavendran JV, Coderre TJ Tags: Anesth Analg Source Type: research

Pregabalin Treatment of a Patient With Complex Regional Pain Syndrome
We present a patient with CRPS type 1 accompanied by a psychiatric disorder to discuss the relationship between CRPS and psychiatric disease and to emphasize the response of this case to treatment with pregabalin.
Source: Pediatric Neurology - January 9, 2014 Category: Neurology Authors: Sema Saltık, Hatice Gulhan Sözen, Senem Basgul, Elif Yuksel Karatoprak, Afitap Içağasıoğlu Tags: Clinical Observations Source Type: research

Pregabalin Treatment in a Case with Complex Regional Pain Syndrome
We present a case diagnosed with CRPS type 1 accompanied by a psychiatric disorder to discuss the relationship between CRPS and psychiatric disease and to emphasize the response of this case to pregabalin treatment.
Source: Pediatric Neurology - January 9, 2014 Category: Neurology Authors: Sema Saltık, Hatice Gulhan Sözen, Senem Basgul, Elif Yuksel Karatoprak, Afitap Içağasıoğlu Tags: Clinical Observations Source Type: research