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Osteo-Cutaneous Trophic Changes in Complex Regional Pain Syndrome and their Reversal with Steroids
Conclusion: Apart from pain relief, steroids therapy is capable of reversing the osteo-cutaneous autonomic changes of CRPS type I.
Source: Neurology India - July 1, 2022 Category: Neurology Authors: Sunil Pradhan Robin Bansal Animesh Das Vibhor Pardasani Hardeep Singh Malhotra Suman Kushwaha Vijay Nath Mishra Source Type: research

Effectiveness of perampanel in managing chronic pain caused by the complex regional pain syndrome: A case report
This report describes a patient with complex regional pain syndrome (CRPS) type I in the right lower leg and foot who responded well to perampanel, an AMPA receptor antagonist, for managing the chronic pain. Patient concern: A 61-year-old woman complained of pain in her right lower leg and foot over a period of 7 year (numeric rating scale: 8) due to CRPS type I. Diagnosis: CRPS type 1. Interventions: Despite the combination of 300 mg pregabalin, 225 mg/1950 mg tramadol/acetaminophen, and 10 mg nortriptyline per day, her right lower leg and foot were nearly disabled due to the severity of the p...
Source: Medicine - December 3, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Pamidronate effect compared with a steroid on complex regional pain syndrome type I: Pilot randomised trial.
CONCLUSIONS: Intravenous pamidronate therapy was safe, well tolerated and appeared as effective as a steroid for pain control for post-stroke CRPS. However, this result should be interpreted with caution, since it included a relatively small number of patients. Further larger controlled studies followed over a longer period are needed to validate these findings and to determine clinical treatment standards. PMID: 26819359 [PubMed - in process]
Source: The Netherlands Journal of Medicine - January 1, 2016 Category: Journals (General) Authors: Eun Young H, Hyeyun K, Sang Hee I Tags: Neth J Med Source Type: research