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Source: European Journal of Pain

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Total 51 results found since Jan 2013.

Characterizing biased visuospatial perception in complex regional pain syndrome
ConclusionsPatients' cognitive strategies will be important to consider when studying inter-individual differences in the cognitive symptomatology and associated cognitive-based rehabilitation procedures in CRPS.SignificanceThe existence of biases in visuospatial perception in Complex Regional Pain Syndrome has been reported but not always systematically replicated. We show that these biases might depend on the type of general rehabilitation program that the patients follow. Patients ’ individual cognitive strategies will be important to consider when studying the cognitive symptomatology of CRPS.
Source: European Journal of Pain - April 22, 2023 Category: Anesthesiology Authors: Lieve Filbrich, Avgustina Kuzminova, Victoria Molitor, Charlotte Verfaille, Dominique Mouraux, Anne Berquin, Olivier Barbier, Xavier Libouton, Val éry Legrain Tags: ORIGINAL ARTICLE Source Type: research

The role of the bone in complex regional pain syndrome 1 —A systematic review
ConclusionThe limited data reviewed revealed certain potential bone-related biomarkers in CRPS. Biomarkers hold the potential to identify patients who may benefit from treatments that influence bone turnover. Thus, this review identifies important areas for future research in CRPS1 patients.
Source: European Journal of Pain - April 9, 2023 Category: Anesthesiology Authors: Gil Kollmann, Maria M. Wertli, Stefan Dudli, Oliver Distler, Florian Brunner Tags: REVIEW ARTICLE Source Type: research

The role of the bone in Complex Regional Pain Syndrome 1 – A systematic review
AbstractThe aim of this systematic review was to appraise and analyze the knowledge on bone-related biochemical and histological biomarkers in Complex Regional Pain Syndrome 1 (CRPS 1).A total of 7 studies were included in the analysis (biochemical analyses n=3, animal study n=1, histological examination n=3). Two studies were classified as having low risk of bias and five studies with a moderate risk of bias. Biochemical analysis indicated an increased bone turnover with increased bone resorption (elevated urinary levels of deoxypyridinoline) and bone formation (increased serum levels of calcitonin, osteoprotegrin and alk...
Source: European Journal of Pain - April 1, 2023 Category: Anesthesiology Authors: Gil Kollmann, Maria M. Wertli, Stefan Dudli, Oliver Distler, Florian Brunner Tags: REVIEW ARTICLE Source Type: research

Biological and psychological early prognostic factors in complex regional pain syndrome: A systematic review
ConclusionsThis study showed an important lack of information on early prognostic factors in CRPS. Only one article investigated the link with psychological characteristics. There is a crucial need of larger studies, with well-defined population using validated measures.
Source: European Journal of Pain - December 14, 2022 Category: Anesthesiology Authors: Marc ‐Henri Louis, Caroline Meyer, Valéry Legrain, Anne Berquin Tags: REVIEW ARTICLE Source Type: research

Molecular and clinical markers of pain relief in complex regional pain syndrome: An observational study
ConclusionWe identified progressively reduced miR-223 as putative biomarker of chronic CRPS pain. Clinically, this study underlines the importance of early diagnosis and treatment showing that high initial pain does not predict unfavourable outcome. Finally, pain relief and recovery of sensory disturbances seem independent processes.
Source: European Journal of Pain - November 29, 2022 Category: Anesthesiology Authors: Ann Kristin Reinhold, Gudrun ‐Karin Kindl, Christopher Dietz, Nathalie Scheu, Katharina Mehling, Alexander Brack, Frank Birklein, Heike L. Rittner Tags: ORIGINAL ARTICLE Source Type: research

Pain ‐autonomic measures reveal nociceptive sensitization in complex regional pain syndrome
ConclusionsThis is the first study demonstrating clinical evidence that pain-related autonomic responses may represent objective tools to quantify sensitization processes along the nociceptive neuraxis in CRPS (e.g., widespread hyperexcitability). Pain-autonomic readouts could help scrutinize mechanisms underlying the development and maintenance of chronic pain in CRPS and provide valuable metrics to detect mechanism-based treatment responses in clinical trials.SignificanceThis study provides clinical evidence that autonomic measures to noxious stimuli can objectively detect sensitization processes along the nociceptive ne...
Source: European Journal of Pain - September 22, 2022 Category: Anesthesiology Authors: P. S. Scheuren, I. De Schoenmacker, J. Rosner, F. Brunner, A. Curt, M. Hubli Tags: ORIGINAL ARTICLE Source Type: research

Assessment of Body Perception Disturbances in Complex Regional Pain Syndrome: a Systematic Review using the COSMIN guideline
ConclusionsThree main assessment methods for CRPS body perception disturbances are currently used. Full psychometric evaluation has not been completed for any of the assessment methods. As a consequence, we could not fully apply the COSMIN guideline. To date, there is no agreement concerning the use of a specific questionnaire or scale. The results indicate a need for further research such as psychometric properties of these questionnaires.
Source: European Journal of Pain - September 6, 2022 Category: Anesthesiology Authors: S. Acapo, T. Osinski, T. Rulleau, A. Dupeyron, J. Nizard Tags: REVIEW ARTICLE Source Type: research

Glucocorticoid treatment in patients with complex regional pain syndrome: A systematic review
ConclusionBased on the present review, there is evidence to support glucocorticoid treatment in CRPS. However, the ideal administration route and dose remain unclear. We therefore recommend future research via an intervention study, as well as studies on the aetiological mechanisms and corresponding optimal treatment because CRPS pathogenesis is only partially understood.
Source: European Journal of Pain - August 19, 2022 Category: Anesthesiology Authors: C. van den Berg, P. N. de Bree, F. J. P. M. Huygen, J. Tiemensma Tags: REVIEW ARTICLE Source Type: research

What do I need to know? Essential educational concepts for complex regional pain syndrome
ConclusionForty-eight concepts were jointly considered ‘very important’ for future CRPS-related educational content. Future research to better understand group differences and to canvas a broader HCP group is warranted.
Source: European Journal of Pain - May 22, 2022 Category: Anesthesiology Authors: E. Moore, F. A. Braithwaite, T. R. Stanton, V. Bellan, G. L. Moseley, C. Berryman Tags: ORIGINAL ARTICLE Source Type: research

Complex regional pain syndrome what is the outcome? ‐ a systematic review of the course and impact of CRPS at 12 months from symptom onset and beyond
ConclusionsResults provide first time quantitative data specific evidence about losses to motor function and long-term compromises to work status. Results demonstrate the ongoing impact of CRPS on hand function and work status is relatively high.
Source: European Journal of Pain - April 18, 2022 Category: Anesthesiology Authors: Selina Johnson, Fiona Cowell, Sharon Gillespie, Andreas Goebel Tags: REVIEW ARTICLE Source Type: research

Pain, disability, and lifestyle: Patients with complex regional pain syndrome compared to chronic musculoskeletal pain ‐ a retrospective analysis
ConclusionIn summary our study supports a more optimistic view on pain in CRPS patients in comparison to MSK and identifies lifestyle factors which might contribute to the pathophysiology like smoking and drinking. Important next steps are the identification of CRPS patients at risk for chronification or – vice versa - with protective factors for pain resolution.
Source: European Journal of Pain - December 27, 2021 Category: Anesthesiology Authors: Gudrun Kindl, Karolin Teichm üller, Fabiola Escolano‐Lozano, Frank Birklein, Heike L. Rittner Tags: ORIGINAL ARTICLE Source Type: research

Pain Relief by Movement Representation Strategies: An Umbrella and Mapping Review with Meta ‐Meta‐Analysis of Motor Imagery, Action Observation and Mirror Therapy
ConclusionResults show that MRM could be effective for chronic musculoskeletal pain, with low to moderate-quality evidence. The results also show a reduction in pain intensity through MT interventions in patients with CRPS, although these results were not found in patients with PLP or poststroke pain.
Source: European Journal of Pain - September 30, 2021 Category: Anesthesiology Authors: Ferran Cuenca ‐Martínez, Álvaro Reina‐Varona, Juan Castillo‐García, Roy La Touche, Santiago Angulo‐Díaz‐Parreño, Luis Suso‐Martí Tags: REVIEW ARTICLE Source Type: research

Spinal Cord Stimulation in Severe Cases of Complex Regional Pain Syndrome: A Retrospective Cohort Study with Long ‐Term Follow‐up
ConclusionPain intensity, depression, pain catastrophizing, pain medication use, and QoL were significantly improved after SCS implantation, with high patient satisfaction rates in CRPS patients. This study supports the continued use of SCS in the treatment of severe CRPS.
Source: European Journal of Pain - July 1, 2021 Category: Anesthesiology Authors: Linda Elise Eriksen, Astrid Juhl Terkelsen, Morten Rune Blichfeldt ‐Eckhardt, Jens Christian H Sørensen, Kaare Meier Tags: ORIGINAL ARTICLE Source Type: research

Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomised trial
ConclusionsVisually changing the CRPS hand to a desired appearance modulates BPD and pain suggesting therapeutic potential for those with refractory CRPS. Further research to optimise this therapeutic effect is required.
Source: European Journal of Pain - March 23, 2021 Category: Anesthesiology Authors: J.S. Lewis, R. Newport, G. Taylor, M. Smith, C.S. McCabe Tags: ORIGINAL ARTICLE Source Type: research

A linguistic analysis of future narratives in adolescents with Complex Regional Pain Syndrome and their pain ‐free peers
ConclusionsSubstantial differences in cognitive and affective words were found between adolescents with and without CRPS. Findings provide novel insights into current understandings of cognitive, affective and social processes in adolescents living with chronic pain, particularly with regard to adolescent developmental trajectories, and may in turn highlight potential targets in psychosocial interventions for adolescents living with chronic pain.SignificanceSocial comparisons are commonly undertaken by adolescents with CRPS in relation to peers, increasing risk for poor cognitive, affective and social outcomes. Findings pr...
Source: European Journal of Pain - February 18, 2021 Category: Anesthesiology Authors: Emy Nimbley, Line Caes, Abigail Jones, Emma Fisher, Melanie Noel, Abbie Jordan Tags: ORIGINAL ARTICLE Source Type: research