• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Discovery of a cysteine-rich peptide with glycation modification from Achyranthes bidentata Blume
Fitoterapia. 2022 Oct 18:105338. doi: 10.1016/j.fitote.2022.105338. Online ahead of print.ABSTRACTCysteine-rich peptides (CRPs) are stable molecules that contain multiple disulphide bonds. Various CRPs are found in plants and animals, representing potential compounds for drug development with diverse activities. Modification of CRPs, such as glycation, has attracted increased attention due to its special structural and functional properties. Hence, this study explored a CRP isolated from the Chinese herb Achyranthes bidentata Blume, which contains a glycation modification. Herein, a reverse phase high-performance liquid ch...
Source: Fitoterapia - October 21, 2022 Category: Biochemistry Authors: Meixi He Yingang Feng Yi Wang Mengchun Cheng Xiaozhe Zhang Lihua Zhang Source Type: research

Potentides: Novel Cysteine-Rich Peptides with Unusual Disulfide Connectivity from Potentilla anserina.
Abstract Cysteine-rich peptides (CRPs), disulfide-constrained peptides with three to five disulfide bonds and molecular weights of 2 to 6 kDa, are generally hyperstable and resistant to thermal, chemical and enzymatic degradation. Here, the discovery and characterization of a novel suite of CRPs, collectively named potentides pA1- pA16 from the root of the medicinal herb Potentilla anserina L, are described. Using a combination of proteomic and transcriptomic methods, we showed that 35-residue potentide pA3, the most abundant member of potentides, exhibits high stability against heat, acidic and proteolytic degrad...
Source: Chembiochem - March 29, 2019 Category: Biochemistry Authors: Shen Y, Xu L, Huang J, Serra A, Yang H, Tam JP Tags: Chembiochem Source Type: research