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Successful treatment of acute worsening complex regional pain syndrome in affected dominant right-hand from secondary pathology of new onset third and fourth digit trigger finger
Case Reports Plast Surg Hand Surg. 2022 Apr 27;9(1):123-125. doi: 10.1080/23320885.2022.2063871. eCollection 2022.ABSTRACT65 year old male with preexisting Complex Regional Pain Syndrome (CRPS) in right dominant hand with sudden onset of right third and fourth digit trigger finger successfully treated with flexor tendon sheath corticosteroid and lidocaine injection resulting in long-term resolution of symptoms without causing widely believed aggravation of CRPS.PMID:35530752 | PMC:PMC9067952 | DOI:10.1080/23320885.2022.2063871
Source: Hand Surgery - May 9, 2022 Category: Surgery Authors: Monika Patel Michael Aiello Source Type: research

Successful Treatment of Long Standing Complex Regional Pain Syndrome with Hyperbaric Oxygen Therapy
We describe a case of long-standing CRPS with multi-limb spread and systemic autonomic features, controlled only with very high dose oral corticosteroids, which led to several complications. Multiple other treatment modalities failed or were insufficient to control the CRPS and allow tapering of the corticosteroids, but the patient had a dramatic response to hyperbaric oxygen therapy (HBOT), allowing a reduction in prednisone dose to just over the physiologic range. When symptoms started to increase several months later, a second course of HBOT treatments allowed reduction in prednisone dose into the physiologic range whil...
Source: Journal of NeuroImmune Pharmacology - December 13, 2019 Category: Drugs & Pharmacology Source Type: research

TRPV1 Channel Contributes to the Behavioral Hypersensitivity in a Rat Model of Complex Regional Pain Syndrome Type 1
This study was carried out in accordance with National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. 8023, revised 1978) and approved by the Animal Ethics Committee of Zhejiang Chinese Medical University. Author Contributions QH performed the western blot, immunostaining, and behavioral test. QW performed the patch clamp experiments. CW supervised the patch clamp experiments. QH and BoyuL performed the behavioral test. YT, XS, and JF analyzed the data and reviewed the manuscript. BoyiL designed, supervised the study, and wrote the manuscript. Funding This project was suppor...
Source: Frontiers in Pharmacology - April 25, 2019 Category: Drugs & Pharmacology Source Type: research

Complex Regional Pain Syndrome Type 1: Analysis of 108 Patients
Conclusion This paper describes the clinical characteristics, therapeutic features and outcome of CRPS type 1 in 108 patients. This syndrome is known to be heterogeneous, and does not always present with the well-known symptoms. We recommend establishing a differential diagnosis including other infectious and inflammatory conditions, and point out the importance of early referral, which enables early treatment.
Source: Reumatologia Clinica - February 22, 2017 Category: Rheumatology Source Type: research

Local anaesthetic sympathetic blockade for complex regional pain syndrome.
CONCLUSIONS: This update's results are similar to the previous versions of this systematic review, and the main conclusions are unchanged. There remains a scarcity of published evidence and a lack of high quality evidence to support or refute the use of local anaesthetic sympathetic blockade for CRPS. From the existing evidence, it is not possible to draw firm conclusions regarding the efficacy or safety of this intervention, but the limited data available do not suggest that LASB is effective for reducing pain in CRPS. PMID: 27467116 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 27, 2016 Category: Journals (General) Authors: O'Connell NE, Wand BM, Gibson W, Carr DB, Birklein F, Stanton TR Tags: Cochrane Database Syst Rev Source Type: research

Early Treatment of Acute Complex Regional Pain Syndrome after Fracture or Injury with Prednisone: Why Is There a Failure to Treat? A Case Series.
Conclusion. Corticosteroids can be an effective treatment option for CRPS after fracture. PMID: 27445622 [PubMed - in process]
Source: Pain Research and Management - July 26, 2016 Category: Anesthesiology Authors: Winston P Tags: Pain Res Manag Source Type: research

Clodronate: new directions of use.
In conclusion, clodronate prevents fractures, decrease osteo-articular pain, is easy to handle, tolerable and had a great cost/benefit relationship. PMID: 26604933 [PubMed - as supplied by publisher]
Source: Clinical Cases in Mineral and Bone Metabolism - December 2, 2015 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research