• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Comorbidities (excluding lymphoma) in Sj ögren’s syndrome
AbstractThe information about comorbidities (excluding lymphoma) in primary Sj ögren’s syndrome (pSS) is relatively scarce. Cardiovascular disease, infections, musculoskeletal conditions or malignancy are likely the most relevant comorbid conditions in pSS. Different infections (particularly oral candidal infections) and fibromyalgia are extremely frequent in the daily clin ical practice. On the other hand, the incidence of cardiovascular events and cancer in pSS is low, so information about them comes from large epidemiological studies or meta-analysis. For this reason, preclinical vascular disease is investigated by d...
Source: Rheumatology - May 13, 2021 Category: Rheumatology Source Type: research

The Cerebrospinal Fluid in Multiple Sclerosis
Conclusions OCB are important biomarkers that can support MRI diagnostics and help to avoid false-positive MS diagnoses. Therefore, the revised McDonalds criteria have increased the importance of the OCB. New biomarkers such as AQP4 have now established themselves in clinical practice, and others such as Anti-MOG and NfL are about to enter clinical routine. An important focus in the search for new biomarkers is the monitoring of therapy efficacy and the prediction of severe side effects. Many other CSF molecules such as CHI3L1, IL-6, or CXCL13 show potential as markers for clinical practice, but further research is nee...
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research

The role of neurology in a medicine-based undiagnosed patient clinic: The Emory Special Diagnostic Clinic experience (P2.190)
Conclusions:This three year experience supports the view that neurology should play a role in special diagnostic clinics which have traditionally been anchored in internal medicine departments. The significant prevalence of functional disorders (10%) was a conservative underestimate given our screening procedures. Those with functional disorders consisted of a heterogeneous mix of complex syndromes accompanied by neuropsychiatric conditions that once recognized, helped prioritize subsequent therapy.Disclosure: Dr. Lazarus has nothing to disclose. Dr. Partin Jr. has nothing to disclose. Dr. Cohen has nothing to disclose. Dr...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lazarus, J. T., Partin, W. C., Cohen, D., Juncos, J. Tags: General Neurology: Practice Improvement and Novel Approaches to Care Source Type: research

Primary Sj ögren's syndrome
Publication date: February 2016 Source:Best Practice & Research Clinical Rheumatology, Volume 30, Issue 1 Author(s): Maureen Rischmueller, Joanna Tieu, Susan Lester Primary Sjögren's syndrome (pSS) is a relatively common autoimmune systemic rheumatic disease. In addition to sicca syndrome and swollen salivary glands, systemic features manifest in the majority of patients, and are severe in 15%, particularly affecting the joints, skin, lungs, and peripheral nervous system. A recent meta-analysis estimated a pooled relative risk of 13.76 for the development of non-Hodgkin lymphoma, particularly in pSS patients ...
Source: Best Practice and Research Clinical Rheumatology - July 20, 2016 Category: Rheumatology Source Type: research

Primary Sjögren's syndrome
Publication date: Available online 13 May 2016 Source:Best Practice & Research Clinical Rheumatology Author(s): Maureen Rischmueller, Joanna Tieu, Susan Lester Primary Sjögren's syndrome (pSS) is a relatively common autoimmune systemic rheumatic disease. In addition to sicca syndrome and swollen salivary glands, systemic features manifest in the majority of patients, and are severe in 15%, particularly affecting the joints, skin, lungs, and peripheral nervous system. A recent meta-analysis estimated a pooled relative risk of 13.76 for the development of non-Hodgkin lymphoma, particularly in pSS patients who h...
Source: Best Practice and Research Clinical Rheumatology - May 12, 2016 Category: Rheumatology Source Type: research

An unusual presentation of Kikuchi-Fujimoto disease.
We describe a 34-year-old African-American female who presented with constitutional symptoms and polyadenopathy on clinical examination and imaging, of which the portacaval and portahepatis lymph nodes were most prominent. An extensive workup was otherwise unremarkable, and biopsy showed histiocytic necrotizing lymphadenitis. Initially, her clinical condition improved spontaneously, and she required only a short course of oral steroids. Three months later, she relapsed with bilateral cervical adenopathy and constitutional symptoms and was successfully managed again with steroids. Our case is unique with respect to (a) port...
Source: Connecticut Medicine - April 1, 2014 Category: Journals (General) Authors: Van den Bergh M, Bauer FA, Posteraro AF, Thumma S, Dasanu CA Tags: Conn Med Source Type: research