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Condition: Multiple Sclerosis
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Total 391 results found since Jan 2013.
Widespread pain with nociplastic features is an independent predictor of low physical activity in people with multiple sclerosis
Exploring the relationship between underlying pain mechanism and physical activity could inform interventions to optimize physical activity in persons with multiple sclerosis (PwMS). This cross-sectional nationwide survey examined whether pain phenotype is a significant predictor of self-reported physical activity in PwMS. The study included 938 persons with self-reported diagnosis of MS (93% reported neurologist-diagnosed MS) who completed surveys of demographic, clinical information, pain intensity, indicators of underlying pain mechanisms (Fibromyalgia Survey Criteria and painDETECT), and physical activity (Godin Leisur...
Source: The Journal of Pain - September 21, 2023 Category: Materials Science Authors: Libak Abou, Daniel Whibley, Daniel J. Clauw, Anna L. Kratz Source Type: research
The Utilization of Low Dose Naltrexone for Chronic Pain
AbstractNaltrexone is a mu-opioid receptor antagonist with a long half-life compared with naloxone. Both of these drugs, along with others, were developed with the intention of reversing the effects of opioid abuse or toxicity. Evidence has also shown that naltrexone has a benefit in preventing relapse by reducing opioid cravings and reducing symptoms of opioid withdrawal. The benefits of this drug were not only shown with opioid abuse. In 1984 this drug was also approved for alcohol abuse. Naltrexone has been proven to decrease alcohol relapse by decreasing the craving. Apart from these approved indications for the use of...
Source: CNS Drugs - July 28, 2023 Category: Neurology Source Type: research
Epidemiology of small intestinal bacterial overgrowth
World J Gastroenterol. 2023 Jun 14;29(22):3400-3421. doi: 10.3748/wjg.v29.i22.3400.ABSTRACTSmall intestinal bacterial overgrowth (SIBO) is defined as an increase in the bacterial content of the small intestine above normal values. The presence of SIBO is detected in 33.8% of patients with gastroenterological complaints who underwent a breath test, and is significantly associated with smoking, bloating, abdominal pain, and anemia. Proton pump inhibitor therapy is a significant risk factor for SIBO. The risk of SIBO increases with age and does not depend on gender or race. SIBO complicates the course of a number of diseases ...
Source: World Journal of Gastroenterology : WJG - June 30, 2023 Category: Gastroenterology Authors: Irina Efremova Roman Maslennikov Elena Poluektova Ekaterina Vasilieva Yury Zharikov Andrey Suslov Yana Letyagina Evgenii Kozlov Anna Levshina Vladimir Ivashkin Source Type: research
51-Year-Old Woman With Fever, Cough, and Myalgias
A 51-year-old woman presented to the emergency department (ED) during the summertime with a 2-day history of fever up to 39.2 °C, nonproductive cough, myalgias, and nausea without associated diarrhea or vomiting. Her medical comorbidities included nicotine dependence with a 20-pack-year smoking history, common variable immune deficiency, quiescent multiple sclerosis not receiving immunomodulatory therapy, heart failure wi th preserved ejection fraction, hypertension, and fibromyalgia. Medications at the time of presentation were nortriptyline, cyclobenzaprine, aspirin, and duloxetine.
Source: Mayo Clinic Proceedings - March 1, 2023 Category: Internal Medicine Authors: Jack McHugh, Ryan Khodadadi, Priya Sampathkumar Tags: Residents ’ clinic Source Type: research
Isotretinoin use for acne is not associated with an increased risk of migraine, fibromyalgia, multiple sclerosis, or neuropathy: A matched, retrospective cohort study
Source: Journal of the American Academy of Dermatology - February 13, 2023 Category: Dermatology Authors: John S. Barbieri Source Type: research
Impact of Treating Depression on Associated Comorbidities: A Systematic Literature Review
Conclusions: Effective treatment of MDD may lead to a reduction in the severity of certain serious comorbidities. These results highlight the importance of appropriate and timely treatment of MDD.PMID:36638539 | DOI:10.4088/PCC.22r03330
Source: Primary Care - January 13, 2023 Category: Primary Care Authors: Alix M Arnaud Teri S Brister Ken Duckworth Phyllis Foxworth Tonya Fulwider Ellison D Suthoff Brian Werneburg Izabela Aleksanderek Marcia L Reinhart Source Type: research
