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Drug: Amitriptyline

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Total 68 results found since Jan 2013.

Is low-dose naltrexone effective in chronic pain management?
J Fam Pract. 2023 Sep;72(7):320-321. doi: 10.12788/jfp.0654.ABSTRACTYES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety profile (strength of recommendation [SOR], B; single randomized controlled trial [RCT]). Low-dose naltrexone significantly reduced pain by 32% in inflammatory conditions and 44% in neuropathic conditions (SOR, B; single retrospective cohort study). Doses as low as 5.4 mg were found to reduce pain in 95% of patients with fibromyalgia (SOR, B; single prospective dose-response study).PMID:37729143 | DOI:10.12788/jfp.0654
Source: The Journal of Family Practice - September 20, 2023 Category: Practice Management Authors: Roxanne Radi Harriet Huang Jason Rivera Corey Lyon Kristen DeSanto Source Type: research

Amitriptyline for fibromyalgia: Off ‐label treatment, but non‐inferior to approved medication
Source: International Journal of Rheumatic Diseases - April 1, 2023 Category: Rheumatology Authors: Cheng Hsien Hung, Yung ‐Heng Lee, James Cheng‐Chung Wei Tags: EDITORIAL Source Type: research

Fibromyalgia: Diagnosis and Management
Am Fam Physician. 2023 Feb;107(2):137-144.ABSTRACTFibromyalgia is a chronic, centralized pain syndrome characterized by disordered processing of painful stimuli. Fibromyalgia is diagnosed more frequently in women and occurs globally, affecting 2% of people in the United States. Patients with fibromyalgia have diffuse chronic pain, poor sleep, fatigue, cognitive dysfunction, and mood disturbances. Comorbid conditions, such as functional somatic syndromes, psychiatric diagnoses, and rheumatologic conditions may be present. The Fibromyalgia Rapid Screening Tool is a helpful screening method for patients with diffuse chronic p...
Source: Pain Physician - February 15, 2023 Category: Anesthesiology Authors: Bradford T Winslow Carmen Vandal Laurel Dang Source Type: research