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Fibromyalgia onset has high impact on work ability in Australians
ConclusionA community pilot survey of Australians with fibromyalgia indicates a high impact on work ability. This occurs from symptom onset and often before diagnosis. Early diagnosis and intervention may provide a window of opportunity to prevent work disability in fibromyalgia.
Source: Internal Medicine Journal - May 30, 2016 Category: Internal Medicine Authors: E.K. Guymer, G.O. Littlejohn, C.K. Brand, R.A. Kwiatek Tags: Original Article Source Type: research

Cannabinoids for fibromyalgia.
CONCLUSIONS: We found no convincing, unbiased, high quality evidence suggesting that nabilone is of value in treating people with fibromyalgia. The tolerability of nabilone was low in people with fibromyalgia. PMID: 27428009 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 17, 2016 Category: Journals (General) Authors: Walitt B, Klose P, Fitzcharles MA, Phillips T, Häuser W Tags: Cochrane Database Syst Rev Source Type: research

Nurse Practitioners' Education, Awareness, and Therapeutic Approaches for the Management of Fibromyalgia
CONCLUSION: Further education is needed for nurse practitioners to increase confidence in diagnosing and managing fibromyalgia.
Source: Orthopaedic Nursing - September 1, 2016 Category: Nursing Tags: Research Source Type: research

Gender Differences in Symptoms, Health-Related Quality of Life, Sleep Quality, Mental Health, Cognitive Performance, Pain-Cognition, and Positive Health in Spanish Fibromyalgia Individuals: The Al- Ándalus Project.
Conclusion. The results of the present study do not support consistent evidence of gender differences in fibromyalgia-related symptoms. However, it seems that detriment of some symptoms (especially pain) in fibromyalgia men compared with their nonfibromyalgia counterparts is greater than those of fibromyalgia women compared with their nonfibromyalgia peers. PMID: 27867309 [PubMed - in process]
Source: Pain Research and Management - November 22, 2016 Category: Anesthesiology Authors: Segura-Jiménez V, Estévez-López F, Soriano-Maldonado A, Álvarez-Gallardo IC, Delgado-Fernández M, Ruiz JR, Aparicio VA Tags: Pain Res Manag Source Type: research

Alterations of brain activity in fibromyalgia patients
Publication date: Available online 10 January 2017 Source:Journal of Clinical Neuroscience Author(s): Passakorn Sawaddiruk, Sahattaya Paiboonworachat, Nipon Chattipakorn, Siriporn C. Chattipakorn Fibromyalgia is a chronic pain syndrome, characterized by widespread musculoskeletal pain with diffuse tenderness at multiple tender points. Despite intense investigations, the pathophysiology of fibromyalgia remains elusive. Evidence shows that it could be due to changes in either the peripheral or central nervous system (CNS). For the CNS changes, alterations in the high brain area of fibromyalgia patients have been investigate...
Source: Journal of Clinical Neuroscience - January 9, 2017 Category: Neuroscience Source Type: research

Fibromyalgia Outcomes Over Time: Results from a Prospective Observational Study in the United States.
CONCLUSION: Fibromyalgia patients reported high levels of burden at both time points, with few significant changes observed over time. Outcomes were variable among patients over time and were better among those with greater pain improvement. PMID: 28077978 [PubMed - in process]
Source: Open Rheumatology Journal - January 13, 2017 Category: Rheumatology Tags: Open Rheumatol J Source Type: research

Oral nonsteroidal anti-inflammatory drugs for fibromyalgia in adults.
CONCLUSIONS: There is only a modest amount of very low-quality evidence about the use of NSAIDs in fibromyalgia, and that comes from small, largely inadequate studies with potential risk of bias. That bias would normally be to increase the apparent benefits of NSAIDs, but no such benefits were seen. Consequently, NSAIDs cannot be regarded as useful for treating fibromyalgia. PMID: 28349517 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - March 27, 2017 Category: Journals (General) Authors: Derry S, Wiffen PJ, Häuser W, Mücke M, Tölle TR, Bell RF, Moore RA Tags: Cochrane Database Syst Rev Source Type: research

Ambroxol for fibromyalgia: one group pretest-posttest open-label pilot study
AbstractA consistent line of investigation proposes that fibromyalgia is a sympathetically maintained neuropathic pain syndrome. Dorsal root ganglia sodium channels may play a major role in fibromyalgia pain transmission. Ambroxol is a secretolytic agent used in the treatment of various airway disorders. Recently, it was discovered that this compound is also an efficient sodium channel blocker with potent anti-neuropathic pain properties. We evaluated the add-on effect of ambroxol to the treatment of fibromyalgia. We studied 25 patients with fibromyalgia. Ambroxol was prescribed at the usual clinical dose of 30  mg PO 3 t...
Source: Clinical Rheumatology - May 2, 2017 Category: Rheumatology Source Type: research

What do people search online concerning the “elusive” fibromyalgia? Insights from a qualitative and quantitative analysis of Google Trends
AbstractFibromyalgia is a chronic disease, characterized by pain, fatigue, and poor sleep quality. Patients and mainly those with chronic diseases tend to search for health-related material online. Google Trends (GT), an online tracking system of Internet hit-search volumes that recently merged with its sister project Google Insights for Search (Google Inc.), was used to explore Internet activity related to fibromyalgia. Digital interest in fibromyalgia and related topics searched worldwide has been reported in the last 13  years. A slight decline in this interest has been observed through the years, remaining stable in t...
Source: Clinical Rheumatology - May 1, 2017 Category: Rheumatology Source Type: research

A low fermentable oligo-di-mono-saccharides and polyols (FODMAP) diet is a balanced therapy for fibromyalgia with nutritional and symptomatic benefits.
CONCLUSIONS: Results are highly encouraging, showing low fermentable oligo-di-mono-saccharides and polyols diets as a nutritionally balanced approach, contributing to weight loss and reducing the severity of FM fibromyalgiasymptoms. PMID: 28627205 [PubMed - in process]
Source: Nutricion Hospitalaria - June 5, 2017 Category: Nutrition Authors: Marum AP, Moreira C, Carus PT, Saraiva F, Guerreiro CS Tags: Nutr Hosp Source Type: research

Mindfulness Meditation for Fibromyalgia: Mechanistic and Clinical Considerations
AbstractPurpose of ReviewFibromyalgia is a disorder characterized by widespread pain and a spectrum of psychological comorbidities, rendering treatment difficult and often a financial burden. Fibromyalgia is a complicated chronic pain condition that requires a multimodal therapeutic approach to optimize treatment efficacy. Thus, it has been postulated that mind-body techniques may prove fruitful in treating fibromyalgia. Mindfulness meditation, a behavioral technique premised on non-reactive sensory awareness, attenuates pain and improves mental health outcomes. However, the impact of mindfulness meditation on fibromyalgia...
Source: Current Rheumatology Reports - July 27, 2017 Category: Rheumatology Source Type: research

Impact of adding a cognitive task while performing physical fitness tests in women with fibromyalgia: A cross-sectional descriptive study
Fibromyalgia symptoms cause a significant reduction in the ability to perform daily life activities. These activities often require the ability to perform more than 1 task at the same time. The aim was to investigate how the addition of a cognitive task modifies the performance in physical fitness tests in fibromyalgia and healthy controls. A total of 61 women participated in this study, 31 of them diagnosed with fibromyalgia by a rheumatologist. They performed 3 physical fitness tests (arm curl, handgrip, and 10-steps stair tests) in 2 conditions: regular (single task [ST]) andwhile thinking in 3 words that were given ...
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Evaluation of carotid-femoral pulse wave velocity, aortic stiffness index, and aortic distensibility in patients with fibromyalgia
ConclusionCFPWV and aortic stiffness seem to be increased and aortic distensibility seems to be decreased in patients with fibromyalgia. Alleviating pain and improving the disease severity may be helpful in preventing cardiovascular risk factors in patients with fibromyalgia.
Source: Clinical Rheumatology - January 11, 2019 Category: Rheumatology Source Type: research

Altered Cervical Spinal Cord Resting ‐State Activity in Fibromyalgia
ConclusionOur results indicate unbalanced activity between the ventral and dorsal cervical spinal cord in fibromyalgia. Increased ventral neural processes and decreased dorsal neural processes may reflect the presence of central sensitization and contribute to fatigue and other bodily symptoms in fibromyalgia.
Source: Arthritis and Rheumatology - February 11, 2019 Category: Rheumatology Authors: Katherine T. Martucci, Kenneth A. Weber, Sean C. Mackey Tags: Original Article Source Type: research

Time to diagnosis of fibromyalgia and factors associated with delayed diagnosis in primary care
Publication date: Available online 4 March 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Omer Gendelman, Howard Amital, Yael Bar-On, Dana Ben-Ami Shor, Daniela Amital, Shmuel Tiosano, Varda Shalev, Gabriel Chodick, Dahlia WeitzmanAbstractFibromyalgia is a complex disorder, and its diagnosis often comprises a challenge for physicians.We aimed to assess the time from the appearance of early symptoms to the definite diagnosis of fibromyalgia and to delineate patient and physician factors associated with this delay.The database of a large healthcare services provider was searched for all fibromyalgia pat...
Source: Best Practice and Research Clinical Rheumatology - March 6, 2019 Category: Rheumatology Source Type: research